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ONTOLOGY REPORT - ANNOTATIONS


Term:angiotensin IV signaling pathway
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Accession:PW:0000458 term browser browse the term
Definition:Angiotensin IV is derived from angiotensin III through the action of aminopeptidase N. The receptor for angiotensin IV has been shown to be the insulin-regulated membrane aminopeptidase. Studies suggest that angiotensin IV signaling activates a number of intracellular second messenger systems and plays a role in vascular remodeling and memory.


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angiotensin IV signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGT angiotensinogen JBrowse link 1 230,702,523 230,714,122 RGD:1582105
G ANPEP alanyl aminopeptidase, membrane JBrowse link 15 89,784,895 89,814,852 RGD:1581742
G LNPEP leucyl and cystinyl aminopeptidase JBrowse link 5 96,934,859 97,037,513 RGD:1581864
G RNPEP arginyl aminopeptidase JBrowse link 1 201,982,648 202,006,143 RGD:1581649

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5944
    signaling pathway 2491
      hormone signaling pathway 559
        peptide and protein hormone signaling pathway 443
          angiotensin signaling pathway 38
            angiotensin IV signaling pathway 4
Path 2
Term Annotations click to browse term
  pathway 5944
    regulatory pathway 3597
      homeostasis pathway 1659
        cardiovascular system homeostasis pathway 422
          renin-angiotensin cascade pathway 47
            angiotensin signaling pathway 38
              angiotensin IV signaling pathway 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.