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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:angiotensin III signaling pathway
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Accession:PW:0000457 term browser browse the term
Definition:Angiotensin III is derived from angiotensin II through the action of aminopeptidase A and in turn is cleaved by aminopeptidase N to generate angiotensin IV. Angiotensin III appears to function in a manner similar to angiotensin II. It plays a role in vasoconstriction and the control of arterial blood pressure. Angiotensin III may be the effective angiotensin peptide in the central nervous system.


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angiotensin III signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11295571 RGD:1582124 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:11295571 RGD:1582124 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:11295571 RGD:1582124 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853 		JBrowse link
G ENPEP glutamyl aminopeptidase ISO RGD PMID:15638741 PMID:16537183 RGD:1581649 RGD:1581742 NCBI chr32:30,553,055...30,639,790
Ensembl chr32:30,553,182...30,638,522 		JBrowse link
angiotensin III signaling pathway via AT1 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:11100981 RGD:1582152 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238 		JBrowse link
angiotensin III signaling pathway via AT2 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16380540 RGD:1582118 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:16380540 RGD:1582118 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4052
    signaling pathway 1939
      hormone signaling pathway 379
        peptide and protein hormone signaling pathway 273
          angiotensin signaling pathway 40
            angiotensin III signaling pathway 4
              angiotensin III signaling pathway via AT1 receptor 2
              angiotensin III signaling pathway via AT2 receptor 2
Path 2
Term Annotations click to browse term
  pathway 4052
    regulatory pathway 2511
      homeostasis pathway 1305
        cardiovascular system homeostasis pathway 264
          renin-angiotensin cascade pathway 44
            angiotensin signaling pathway 40
              angiotensin III signaling pathway 4
                angiotensin III signaling pathway via AT1 receptor 2
                angiotensin III signaling pathway via AT2 receptor 2
paths to the root