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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:angiotensin III signaling pathway
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Accession:PW:0000457 term browser browse the term
Definition:Angiotensin III is derived from angiotensin II through the action of aminopeptidase A and in turn is cleaved by aminopeptidase N to generate angiotensin IV. Angiotensin III appears to function in a manner similar to angiotensin II. It plays a role in vasoconstriction and the control of arterial blood pressure. Angiotensin III may be the effective angiotensin peptide in the central nervous system.


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angiotensin III signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen TAS RGD PMID:11295571 RGD:1582124 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a TAS RGD PMID:11295571 RGD:1582124 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b TAS RGD PMID:11295571 RGD:1582124 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 TAS RGD PMID:11295571 RGD:1582124 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Enpep glutamyl aminopeptidase IDA RGD PMID:16537183 RGD:1581649 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
angiotensin III signaling pathway via AT1 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IMP RGD PMID:11100981 RGD:1582152 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:11100981 RGD:1582152 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b IMP RGD PMID:11100981 RGD:1582152 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232 		JBrowse link
angiotensin III signaling pathway via AT2 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IMP RGD PMID:16380540 RGD:1582118 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:16380540 RGD:1582118 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      hormone signaling pathway 624
        peptide and protein hormone signaling pathway 439
          angiotensin signaling pathway 41
            angiotensin III signaling pathway 5
              angiotensin III signaling pathway via AT1 receptor 3
              angiotensin III signaling pathway via AT2 receptor 2
Path 2
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      homeostasis pathway 1773
        cardiovascular system homeostasis pathway 423
          renin-angiotensin cascade pathway 52
            angiotensin signaling pathway 41
              angiotensin III signaling pathway 5
                angiotensin III signaling pathway via AT1 receptor 3
                angiotensin III signaling pathway via AT2 receptor 2
paths to the root