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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent
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Accession:PW:0000401 term browser browse the term
Definition:The route of homocysteine remethyation to methionine that mainly occurs in the liver and requires betaine as the methyl donor.
Synonyms:related_synonym: SMP:00123



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remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy adenosylhomocysteinase ISO SMPDB SMP:00123 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 ISO SMPDB SMP:00123 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase IDA
ISO
SMPDB
RGD
PMID:15845641 PMID:20814827 PMID:20346934 SMP:00123, RGD:1359026, RGD:7242426, RGD:7242428 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Chdh choline dehydrogenase ISO SMPDB SMP:00123 NCBI chr16:5,194,269...5,225,541
Ensembl chr16:5,194,269...5,225,537
JBrowse link
G Mat2a methionine adenosyltransferase 2A ISO SMPDB SMP:00123 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit ISO SMPDB SMP:00123 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO SMPDB SMP:00123 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase ISO SMPDB SMP:00123 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1854
      metabolic pathway of other amino acids 141
        homocysteine metabolic pathway 36
          remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent 8
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3867
      homeostasis pathway 1773
        organic chemical homeostasis pathway 438
          S-adenosylmethionine homeostasis pathway 289
            homocysteine metabolic pathway 36
              remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent 8
paths to the root