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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:transsulfuration pathway of homocysteine metabolism
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Accession:PW:0000400 term browser browse the term
Definition:The transulfuration pathway is one of the two routes of homocysteine metabolism. It allows for the transfer of sulfur from methionine to cysteine. 70% of cysteine is then converted to glutathione and the remainder ends up as either taurine or pyruvate and sulfate.
Synonyms:related_synonym: SMP:00455

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transsulfuration pathway of homocysteine metabolism term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase ISO SMPDB
RGD
PMID:20162368 SMP:00455, RGD:7242427 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cdo1 cysteine dioxygenase type 1 ISO RGD PMID:20162368 RGD:7242427 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Csad cysteine sulfinic acid decarboxylase ISO RGD PMID:20162368 RGD:7242427 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
G Cth cystathionine gamma-lyase ISO SMPDB
RGD
PMID:20162368 SMP:00455, RGD:7242427 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1854
      metabolic pathway of other amino acids 141
        homocysteine metabolic pathway 36
          transsulfuration pathway of homocysteine metabolism 4
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3867
      homeostasis pathway 1773
        organic chemical homeostasis pathway 438
          S-adenosylmethionine homeostasis pathway 289
            homocysteine metabolic pathway 36
              transsulfuration pathway of homocysteine metabolism 4
paths to the root