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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:remethylation pathway of homocysteine metabolism - cobalamin dependent
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Accession:PW:0000399 term browser browse the term
Definition:The predominant route of homocysteine remethylation to methionine that requires the 5-methyl tetrahydrofolate 1 carbon donor and as such, engages folate metabolism.



show annotations for term's descendants           Sort by:
remethylation pathway of homocysteine metabolism - cobalamin dependent term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfr methylenetetrahydrofolate reductase ISO RGD PMID:20814827 RGD:7242426 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IDA
ISO
RGD PMID:15845641 PMID:20814827 RGD:1359026, RGD:7242426 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:15979034 PMID:20814827 RGD:1359037, RGD:7242426 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1854
      metabolic pathway of other amino acids 141
        homocysteine metabolic pathway 36
          remethylation pathway of homocysteine metabolism - cobalamin dependent 3
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3867
      homeostasis pathway 1773
        organic chemical homeostasis pathway 438
          S-adenosylmethionine homeostasis pathway 289
            homocysteine metabolic pathway 36
              remethylation pathway of homocysteine metabolism - cobalamin dependent 3
paths to the root