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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:spermidine metabolic pathway
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Accession:PW:0000396 term browser browse the term
Definition:Polyamine metabolism plays important roles in a number of cellular processes. Spermidine and spermine are formed in two consecutive reactions carried out by distinct enzymes that employ the decarboxylated form of AdoMet as an aminopropyl donor.
Synonyms:related_synonym: spermidine metabolic process


show annotations for term's descendants           Sort by:
spermidine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 ISS
ISO
EXP		 SMPDB
RGD		 PMID:10430362 PMID:10712236 PMID:1415709 SMP:00445, RGD:1578320, RGD:7242911, RGD:7242912 NCBI chr 6:110,814,617...110,895,713
Ensembl chr 6:110,874,770...110,898,879 		JBrowse link
G MAT2A methionine adenosyltransferase 2A EXP SMPDB SMP:00445 NCBI chr 2:85,539,168...85,545,281
Ensembl chr 2:85,539,168...85,545,281 		JBrowse link
G MAT2B methionine adenosyltransferase 2 non-catalytic beta subunit EXP SMPDB SMP:00445 NCBI chr 5:163,503,064...163,519,354
Ensembl chr 5:163,503,114...163,519,558 		JBrowse link
G ODC1 ornithine decarboxylase 1 ISS
ISO
EXP		 SMPDB
RGD		 PMID:10430362 PMID:1415709 PMID:2292587 SMP:00445, RGD:1578320, RGD:7242912, RGD:7242932 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:2292587 RGD:7242932 NCBI chr  X:23,783,173...23,786,210
Ensembl chr  X:23,783,173...23,786,210 		JBrowse link
G SMS spermine synthase EXP SMPDB SMP:00445 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837 		JBrowse link
G SRM spermidine synthase TAS
ISO
EXP		 SMPDB
RGD		 PMID:23073625 PMID:16931179 PMID:2292587 SMP:00445, RGD:7242425, RGD:7242920, RGD:7242932 NCBI chr 1:11,054,589...11,060,018
Ensembl chr 1:11,054,584...11,060,020 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    classic metabolic pathway 1803
      biogenic amines and polyamines metabolic pathway 28
        polyamine metabolic pathway 13
          spermidine metabolic pathway 7
Path 2
Term Annotations click to browse term
  pathway 5957
    regulatory pathway 3600
      homeostasis pathway 1667
        organic chemical homeostasis pathway 429
          S-adenosylmethionine homeostasis pathway 277
            polyamine metabolic pathway 13
              spermidine metabolic pathway 7
paths to the root