Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:angiotensin signaling pathway
go back to main search page
Accession:PW:0000245 term browser browse the term
Definition:Angiotensin peptides Ang II, Ang III, Ang IV and Ang (1-7) generated from a single precursor protein - angiotensinogen - regulate an array of physiological and pathophysiological processes.


show annotations for term's descendants           Sort by:
angiotensin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:12676165 RGD:1566511 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
angiotensin (1-7) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:10642323 PMID:15283675 RGD:1581953 RGD:1598433 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G ACE2 angiotensin converting enzyme 2 ISO RGD PMID:15638741 RGD:1581742 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:15951342 RGD:1581938 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO RGD PMID:15951342 PMID:16520407 RGD:1581931 RGD:1581938 NCBI chr 6:157,774,098...157,799,983
Ensembl chr 6:162,801,416...162,802,393 		JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:10642323 PMID:15638741 PMID:16520407 RGD:1581742 RGD:1581931 RGD:1581953 NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119 		JBrowse link
angiotensin II signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:15638741 RGD:1581742 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:16141358 RGD:1581847 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:15590154 RGD:1579760 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:14657020 RGD:1566502 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:14684844 RGD:1582323 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384 		JBrowse link
G CMA1 chymase 1 ISO RGD PMID:15638741 PMID:15869764 RGD:1581742 RGD:1581745 NCBI chr14:5,277,269...5,280,335
Ensembl chr14:23,400,345...23,403,548 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:16269269 RGD:1600094 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO RGD PMID:12661921 RGD:1580992 NCBI chr12:10,196,712...10,210,432
Ensembl chr12:10,445,202...10,461,071 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO RGD PMID:14585963 RGD:1581775 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PLA2G6 phospholipase A2 group VI ISO RGD PMID:17613534 RGD:12910844 NCBI chr22:18,998,060...19,094,507
Ensembl chr22:36,849,794...36,919,509
Ensembl chr22:36,849,794...36,919,509 		JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:16113073 RGD:1642674 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855 		JBrowse link
angiotensin II signaling pathway via AT1 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16141358 RGD:1581847 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:9287353 PMID:10977869 PMID:12446719 PMID:14559250 RGD:1581825 RGD:2316188 RGD:5133683 RGD:629553 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G AGTRAP angiotensin II receptor associated protein ISO RGD PMID:17875818 RGD:2314353 NCBI chr 1:10,498,245...10,512,906
Ensembl chr 1:11,715,672...11,730,326 		JBrowse link
G ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ISO RGD PMID:14559250 RGD:2316188 NCBI chr11:67,763,944...67,831,728
Ensembl chr11:70,985,926...71,028,342 		JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:16304060 RGD:5133417 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:16304060 RGD:5133417 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517 		JBrowse link
G GNA11 G protein subunit alpha 11 ISO RGD PMID:16141358 RGD:1581847 NCBI chr19:2,120,398...2,149,161
Ensembl chr19:3,074,483...3,102,124 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:16304060 RGD:5133417 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066 		JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:16304060 RGD:5133417 NCBI chr22:6,579,664...6,789,846
Ensembl chr22:24,353,533...24,509,560 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:16304060 RGD:5133417 NCBI chr10:115,776,236...116,026,221
Ensembl chr10:119,200,688...119,450,809 		JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:16304060 RGD:5133417 NCBI chr 5:172,704,978...172,744,907
Ensembl chr 5:179,790,662...179,807,410 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:9287353 PMID:9314843 RGD:5133683 RGD:6478796 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G LOC100986730 guanine nucleotide-binding protein G(q) subunit alpha ISO RGD PMID:16141358 RGD:1581847 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849 		JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:12588881 RGD:5133418 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955 		JBrowse link
G TYK2 tyrosine kinase 2 ISO RGD PMID:9314843 RGD:6478796 NCBI chr19:9,901,612...9,932,623
Ensembl chr19:10,565,490...10,594,541 		JBrowse link
angiotensin II signaling pathway via AT2 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16286564 PMID:16286568 PMID:22949090 RGD:1582434 RGD:1582435 RGD:7401256 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:10977869 PMID:22949090 RGD:1581825 RGD:7401256 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
G CNKSR1 connector enhancer of kinase suppressor of Ras 1 ISO RGD PMID:20889352 RGD:5133679 NCBI chr 1:25,438,092...25,450,953
Ensembl chr 1:26,505,513...26,517,225 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO RGD PMID:18804122 RGD:5133675 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:20889352 RGD:5133679 NCBI chr12:32,811,533...32,834,958
Ensembl chr12:33,063,434...33,084,994 		JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:22949090 RGD:7401256 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:22949090 RGD:7401256 NCBI chr 1:111,925,668...111,971,941
Ensembl chr 1:111,154,060...111,198,768 		JBrowse link
G MTUS1 microtubule associated scaffold protein 1 ISO RGD PMID:20889352 RGD:5133679 NCBI chr 8:16,863,307...17,020,684 JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO RGD PMID:18804122 RGD:5133675 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830 		JBrowse link
G SLC9A6 solute carrier family 9 member A6 ISO RGD PMID:20889352 RGD:5133679 NCBI chr  X:125,099,378...125,171,161
Ensembl chr  X:135,378,094...135,439,781 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:20889352 RGD:5133679 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 ISO RGD PMID:20889352 RGD:5133679 NCBI chr11:108,938,414...109,133,819
Ensembl chr11:112,780,380...112,977,164 		JBrowse link
angiotensin III signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11295571 RGD:1582124 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:11295571 RGD:1582124 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:11295571 RGD:1582124 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
G ENPEP glutamyl aminopeptidase ISO RGD PMID:15638741 PMID:16537183 RGD:1581649 RGD:1581742 NCBI chr 4:102,969,397...103,056,978
Ensembl chr 4:113,532,126...113,620,654 		JBrowse link
angiotensin III signaling pathway via AT1 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:11100981 RGD:1582152 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
angiotensin III signaling pathway via AT2 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16380540 RGD:1582118 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:16380540 RGD:1582118 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
angiotensin IV signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11282364 RGD:1582105 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane ISO RGD PMID:15638741 PMID:16537183 RGD:1581649 RGD:1581742 NCBI chr15:68,479,349...68,509,238
Ensembl chr15:87,681,826...87,703,713 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:11282364 PMID:12591177 RGD:1581864 RGD:1582105 NCBI chr 5:92,247,060...92,348,900
Ensembl chr 5:97,842,110...97,893,876 		JBrowse link
G RNPEP arginyl aminopeptidase ISO RGD PMID:16537183 RGD:1581649 NCBI chr 1:177,579,349...177,602,865
Ensembl chr 1:181,880,404...181,903,906 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4060
    signaling pathway 1938
      hormone signaling pathway 379
        peptide and protein hormone signaling pathway 272
          angiotensin signaling pathway 40
            angiotensin (1-7) signaling pathway 5
            angiotensin II signaling pathway + 33
            angiotensin III signaling pathway + 4
            angiotensin IV signaling pathway 4
Path 2
Term Annotations click to browse term
  pathway 4060
    regulatory pathway 2513
      homeostasis pathway 1302
        cardiovascular system homeostasis pathway 265
          renin-angiotensin cascade pathway 44
            angiotensin signaling pathway 40
              angiotensin (1-7) signaling pathway 5
              angiotensin II signaling pathway + 33
              angiotensin III signaling pathway + 4
              angiotensin IV signaling pathway 4
paths to the root