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ONTOLOGY REPORT - ANNOTATIONS


Term:innate immune response pathway
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Accession:PW:0000234 term browser browse the term
Definition:The innate immune response - a universal and ancient form of host defense against infection - is a first line of response to various pathogens and also to damaged cells. It plays a role in stimulating adaptive immunity; molecules generated during innate responses act as second signals that can impact on both the magnitude and the nature of the adaptive response.


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innate immune response pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:1580257
classical complement pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1580273
G C4a complement C4A JBrowse link 20 2,651,599 2,678,183 RGD:1580273
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:1580273
complement system pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:6907045
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:6907045
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:6907045
G C1qa complement C1q A chain JBrowse link 5 155,261,254 155,264,101 RGD:6907045
G C1qb complement C1q B chain JBrowse link 5 155,246,444 155,251,995 RGD:6907045
G C1qc complement C1q C chain JBrowse link 5 155,255,013 155,258,631 RGD:6907045
G C1r complement C1r JBrowse link 4 157,126,060 157,136,825 RGD:6907045
G C1s complement C1s JBrowse link 4 157,143,592 157,155,592 RGD:6907045
G C2 complement C2 JBrowse link 20 4,542,340 4,561,152 RGD:6907045
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:6907045
G C3ar1 complement C3a receptor 1 JBrowse link 4 155,681,767 155,691,240 RGD:6907045
G C4b complement C4B (Chido blood group) JBrowse link 20 4,302,344 4,316,752 RGD:6907045
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:6907045
G C4bpb complement component 4 binding protein, beta JBrowse link 13 47,387,173 47,398,115 RGD:6907045
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:6907045
G C5ar1 complement C5a receptor 1 JBrowse link 1 78,186,777 78,195,132 RGD:6907045
G C6 complement C6 JBrowse link 2 54,460,333 54,533,801 RGD:6907045
G C7 complement C7 JBrowse link 2 54,707,621 54,781,624 RGD:6907045
G C8a complement C8 alpha chain JBrowse link 5 124,348,536 124,403,117 RGD:6907045
G C8b complement C8 beta chain JBrowse link 5 124,298,269 124,338,055 RGD:6907045
G C8g complement C8 gamma chain JBrowse link 3 2,724,616 2,727,616 RGD:6907045
G C9 complement C9 JBrowse link 2 55,775,562 55,823,807 RGD:6907045
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:6907045
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:2326180
RGD:6907045
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:6907045
G Cfb complement factor B JBrowse link 20 4,536,206 4,542,073 RGD:6907045
G Cfd complement factor D JBrowse link 7 12,634,216 12,635,939 RGD:6907045
G Cfh complement factor H JBrowse link 13 56,979,155 57,080,540 RGD:6907045
G Cfi complement factor I JBrowse link 2 235,264,149 235,305,779 RGD:6907045
G Cpb2 carboxypeptidase B2 JBrowse link 15 57,290,849 57,339,762 RGD:6907045
G Cr1l complement C3b/C4b receptor 1 like JBrowse link 13 113,824,886 113,872,097 RGD:6907045
G Cr2 complement C3d receptor 2 JBrowse link 13 113,890,274 113,927,824 RGD:6907045
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:6907045
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:6907045
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:6907045
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:6907045
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6907045
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:6907045
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6907045
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:6907045
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:6907045
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:6907045
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:6907045
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:6907045
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:6907045
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:6907045
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:6907045
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:6907045
G Kng2l1 kininogen 2-like 1 RGD:6907045
G Masp1 mannan-binding lectin serine peptidase 1 JBrowse link 11 80,736,424 80,806,278 RGD:6907045
G Masp2 mannan-binding lectin serine peptidase 2 JBrowse link 5 165,415,105 165,429,857 RGD:6907045
G Mbl1 mannose-binding lectin (protein A) 1 JBrowse link 16 18,736,154 18,742,193 RGD:6907045
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:6907045
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:6907045
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6907045
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:6907045
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:6907045
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:6907045
G Pros1 protein S JBrowse link 7 1,206,648 1,288,140 RGD:6907045
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:6907045
G Serpina5 serpin family A member 5 JBrowse link 6 127,753,152 127,772,403 RGD:6907045
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:6907045
G Serpind1 serpin family D member 1 JBrowse link 11 87,913,814 87,924,880 RGD:6907045
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6907045
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:6907045
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:6907045
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:6907045
G Thbd thrombomodulin JBrowse link 3 142,748,673 142,752,325 RGD:6907045
G Vwf von Willebrand factor JBrowse link 4 158,085,059 158,219,525 RGD:6907045
inflammatory response pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:1549857
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:4892591
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:4892591
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:4892591
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:1582329
interleukin-1 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aim2 absent in melanoma 2 JBrowse link 13 91,919,834 91,963,080 RGD:5490211
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:5490210
RGD:6484113
RGD:5490211
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6484113
G Erc1 ELKS/RAB6-interacting/CAST family member 1 JBrowse link 4 152,087,393 152,380,023 RGD:6484113
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6484113
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:6484113
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:5490209
RGD:6484113
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:5490209
RGD:6484113
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:5490209
RGD:6484113
RGD:5130945
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:5490209
RGD:6484113
G Il1rap interleukin 1 receptor accessory protein JBrowse link 11 77,456,648 77,593,208 RGD:5490209
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:5490209
RGD:6484113
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:5490215
RGD:6484113
RGD:5490218
G Irak2 interleukin-1 receptor-associated kinase 2 JBrowse link 4 145,594,575 145,651,066 RGD:5490215
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 7 64,922,830 64,982,224 RGD:6484113
G Irak4 interleukin-1 receptor-associated kinase 4 JBrowse link 7 135,803,723 135,831,006 RGD:5490215
RGD:6484113
RGD:5490218
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6484113
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6484113
G Map3k3 mitogen activated protein kinase kinase kinase 3 JBrowse link 10 94,280,703 94,349,372 RGD:6484113
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:5490215
RGD:6484113
RGD:5490218
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6484113
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:5490215
RGD:6484113
RGD:5490218
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6484113
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 10 57,692,474 57,747,608 RGD:5490211
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:5490210
RGD:5490211
G Peli1 pellino E3 ubiquitin protein ligase 1 JBrowse link 14 106,008,086 106,062,566 RGD:5490215
G Peli2 pellino E3 ubiquitin protein ligase family member 2 JBrowse link 15 24,942,218 25,086,350 RGD:5490215
G Peli3 pellino E3 ubiquitin protein ligase family member 3 JBrowse link 1 220,191,209 220,204,032 RGD:5490215
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:6484113
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:6484113
G Prkci protein kinase C, iota JBrowse link 2 115,941,998 116,002,550 RGD:6484113
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:6484113
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:5490210
RGD:5490211
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6484113
G Sigirr single Ig and TIR domain containing JBrowse link 1 213,898,395 213,907,697 RGD:5490209
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6484113
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 JBrowse link 7 121,350,953 121,382,100 RGD:5490215
RGD:6484113
RGD:5490218
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 JBrowse link 1 1,999,574 2,017,574 RGD:5490215
RGD:6484113
RGD:5490218
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 JBrowse link X 54,035,958 54,090,282 RGD:5490218
G Ticam2 toll-like receptor adaptor molecule 2 JBrowse link 18 40,555,106 40,572,569 RGD:6484113
G Tollip toll interacting protein JBrowse link 1 214,823,993 214,844,861 RGD:5490218
RGD:6484113
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:5490215
RGD:6484113
RGD:5130945
RGD:5490218
G Ube2n ubiquitin-conjugating enzyme E2N JBrowse link 7 36,610,147 36,640,190 RGD:5490215
RGD:6484113
RGD:5490218
G Ube2v1 ubiquitin conjugating enzyme E2 V1 JBrowse link 3 164,343,833 164,366,684 RGD:5490215
RGD:6484113
RGD:5490218
interleukin-6 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:6484113
G Adam10 ADAM metallopeptidase domain 10 JBrowse link 8 77,107,355 77,237,483 RGD:5686846
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:5686834
RGD:5686846
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6484113
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:6484113
G Cebpd CCAAT/enhancer binding protein delta JBrowse link 11 89,008,008 89,009,146 RGD:6484113
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6484113
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:6484113
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6484113
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:6484113
G Gab1 GRB2-associated binding protein 1 JBrowse link 19 30,794,290 30,903,819 RGD:6484113
G Gab2 GRB2-associated binding protein 2 JBrowse link 1 162,082,876 162,283,379 RGD:6484113
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:5686834
RGD:6484113
G Hck HCK proto-oncogene, Src family tyrosine kinase JBrowse link 3 148,579,917 148,623,026 RGD:6484113
G Hsp90b1 heat shock protein 90 beta family member 1 JBrowse link 7 27,226,570 27,240,533 RGD:6484113
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1580493
RGD:11062097
RGD:6484113
RGD:5686839
RGD:5686834
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:5686834
RGD:6484113
RGD:5686839
G Il6st interleukin 6 signal transducer JBrowse link 2 44,279,199 44,319,427 RGD:5686834
RGD:6484113
RGD:5686900
RGD:5686839
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:6484113
G Jak1 Janus kinase 1 JBrowse link 5 119,982,503 120,091,452 RGD:5686839
RGD:6484113
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:5686839
RGD:6484113
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6484113
G Junb JunB proto-oncogene, AP-1 transcription factor subunit JBrowse link 19 26,092,972 26,094,756 RGD:6484113
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:6484113
G Lmo4 LIM domain only 4 JBrowse link 2 250,218,635 250,235,435 RGD:6484113
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:6484113
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6484113
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6484113
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6484113
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6484113
G Mitf melanocyte inducing transcription factor JBrowse link 4 130,172,484 130,425,496 RGD:6484113
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6484113
G Pias1 protein inhibitor of activated STAT, 1 JBrowse link 8 67,771,720 67,869,015 RGD:6484113
G Pias3 protein inhibitor of activated STAT, 3 JBrowse link 2 198,821,377 198,831,533 RGD:6484113
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:6484113
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:6484113
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:6484113
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:5686834
RGD:6484113
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:6484113
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:6484113
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:5686834
RGD:6484113
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:5686834
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:5686834
RGD:6484113
RGD:5686839
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:5686834
RGD:6484113
RGD:5686839
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6484113
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6484113
G Tyk2 tyrosine kinase 2 JBrowse link 8 22,118,224 22,149,807 RGD:5686839
RGD:6484113
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:6484113
lectin complement pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:4889148
NOD-like receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:6907045
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:6907045
G Card6 caspase recruitment domain family, member 6 JBrowse link 2 54,810,676 54,824,050 RGD:6907045
G Card9 caspase recruitment domain family, member 9 JBrowse link 3 3,798,346 3,806,841 RGD:6907045
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:6907045
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6907045
G Ccl12 chemokine (C-C motif) ligand 12 JBrowse link 10 69,476,866 69,478,416 RGD:6907045
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6907045
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6907045
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:6907045
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6907045
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:6907045
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:6907045
G Hsp90b1 heat shock protein 90 beta family member 1 JBrowse link 7 27,226,570 27,240,533 RGD:6907045
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6907045
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:6907045
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6907045
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6907045
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6907045
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:6907045
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6907045
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:6907045
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6907045
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:6907045
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:6907045
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6907045
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6907045
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6907045
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6907045
G Mefv MEFV innate immuity regulator, pyrin JBrowse link 10 12,045,813 12,056,229 RGD:6907045
G Naip5 NLR family, apoptosis inhibitory protein 5 JBrowse link 2 30,427,827 30,478,894 RGD:6907045
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6907045
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6907045
G Nfkbib NFKB inhibitor beta JBrowse link 1 86,941,073 86,948,845 RGD:6907045
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 10 57,692,474 57,747,608 RGD:6907045
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:6907045
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:6907045
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:6907045
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1643119
RGD:6907045
G Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 JBrowse link 8 60,760,040 60,799,364 RGD:6907045
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:6907045
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6907045
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:6907045
G Sugt1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone JBrowse link 15 61,873,158 61,913,983 RGD:6907045
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6907045
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:6907045
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6907045
pro-inflammatory cytokine mediated pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:15090820
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:15090820
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:15090820
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:15090820
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:15090820
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:15090820
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:15090820
receptor for advanced glycation end-products signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7245565
Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg12 autophagy related 12 JBrowse link 18 40,721,799 40,732,143 RGD:6907045
G Atg5 autophagy related 5 JBrowse link 20 49,301,783 49,393,147 RGD:6907045
G Azi2 5-azacytidine induced 2 JBrowse link 8 126,411,030 126,435,581 RGD:6907045
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6907045
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6907045
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6907045
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:6907045
G Ddx3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 JBrowse link Y 1,217,800 1,238,454 RGD:6907045
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:6907045
G Ddx3y DEAD-box helicase 3, Y-linked JBrowse link 13 105,408,179 105,411,348 RGD:6907045
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:6907045
G Dhx58 DEXH-box helicase 58 JBrowse link 10 88,599,722 88,611,562 RGD:6907045
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:6907045
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 3 48,557,696 48,604,097 RGD:6907045
G Ifna1 interferon, alpha 1 JBrowse link 5 106,951,822 106,952,908 RGD:6907045
G Ifna11 interferon alpha family, gene 11 JBrowse link 5 107,504,741 107,505,783 RGD:6907045
G Ifna2 interferon alpha 2 JBrowse link 5 107,416,117 107,416,695 RGD:6907045
G Ifna4 interferon, alpha 4 JBrowse link 5 106,922,563 106,923,132 RGD:6907045
G Ifna5 interferon, alpha 5 JBrowse link 5 107,039,347 107,039,925 RGD:6907045
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:6907045
G Ifnk interferon kappa JBrowse link 5 50,631,217 50,634,142 RGD:6907045
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6907045
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon JBrowse link 13 48,031,325 48,056,394 RGD:6907045
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:6907045
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:6907045
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6907045
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:6907045
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:6907045
G Isg15 ISG15 ubiquitin-like modifier JBrowse link 5 173,624,862 173,629,124 RGD:6907045
G LOC100911527 interferon alpha-12-like JBrowse link 5 87,328,395 87,328,946 RGD:6907045
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:6907045
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:6907045
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:6907045
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6907045
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:6907045
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:6907045
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6907045
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6907045
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6907045
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:6907045
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6907045
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6907045
G Nfkbib NFKB inhibitor beta JBrowse link 1 86,941,073 86,948,845 RGD:6907045
G Nlrx1 NLR family member X1 JBrowse link 8 48,583,559 48,600,203 RGD:6907045
G Otud5 OTU deubiquitinase 5 JBrowse link X 15,471,212 15,504,372 RGD:6907045
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 8 21,669,236 21,680,615 RGD:6907045
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6907045
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:6907045
G Rnf125 ring finger protein 125 JBrowse link 18 15,193,226 15,225,454 RGD:6907045
G Tank TRAF family member-associated NFKB activator JBrowse link 3 47,439,007 47,515,706 RGD:6907045
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:6907045
G Tbkbp1 TBK1 binding protein 1 JBrowse link 10 85,071,058 85,085,596 RGD:6907045
G Tkfc triokinase and FMN cyclase JBrowse link 1 226,642,901 226,657,698 RGD:6907045
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6907045
G Tradd TNFRSF1A-associated via death domain JBrowse link 19 37,214,461 37,221,099 RGD:6907045
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:6907045
G Traf3 Tnf receptor-associated factor 3 JBrowse link 6 135,610,698 135,720,247 RGD:6907045
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:6907045
G Trim25 tripartite motif-containing 25 JBrowse link 10 76,343,847 76,362,159 RGD:6907045
Toll-like receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6907045
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:6907045
G Akt3 AKT serine/threonine kinase 3 JBrowse link 13 95,076,308 95,348,913 RGD:6907045
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6907045
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6907045
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6907045
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:6907045
RGD:7247704
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:6907045
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:6907045
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6907045
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6907045
G Ctsk cathepsin K JBrowse link 2 196,655,469 196,666,447 RGD:6907045
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6907045
G Cxcl11 C-X-C motif chemokine ligand 11 JBrowse link 14 17,195,395 17,198,170 RGD:6907045
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:6907045
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:6907045
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6907045
G Ifna1 interferon, alpha 1 JBrowse link 5 106,951,822 106,952,908 RGD:6907045
G Ifna11 interferon alpha family, gene 11 JBrowse link 5 107,504,741 107,505,783 RGD:6907045
G Ifna2 interferon alpha 2 JBrowse link 5 107,416,117 107,416,695 RGD:6907045
G Ifna4 interferon, alpha 4 JBrowse link 5 106,922,563 106,923,132 RGD:6907045
G Ifna5 interferon, alpha 5 JBrowse link 5 107,039,347 107,039,925 RGD:6907045
G Ifnar1 interferon alpha and beta receptor subunit 1 JBrowse link 11 31,640,407 31,666,839 RGD:6907045
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:6907045
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6907045
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon JBrowse link 13 48,031,325 48,056,394 RGD:6907045
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:6907045
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:6907045
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6907045
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6907045
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6907045
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:5685014
RGD:6907045
G Irak2 interleukin-1 receptor-associated kinase 2 JBrowse link 4 145,594,575 145,651,066 RGD:5685014
G Irak4 interleukin-1 receptor-associated kinase 4 JBrowse link 7 135,803,723 135,831,006 RGD:5685014
RGD:6907045
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:5685014
RGD:6907045
G Irf5 interferon regulatory factor 5 JBrowse link 4 56,804,477 56,816,271 RGD:6907045
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:6907045
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6907045
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:6907045
RGD:7247704
G LOC100911527 interferon alpha-12-like JBrowse link 5 87,328,395 87,328,946 RGD:6907045
G Ly96 lymphocyte antigen 96 JBrowse link 5 1,972,212 1,989,448 RGD:5685019
RGD:7247704
RGD:6907045
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:6907045
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:6907045
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:6907045
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:6907045
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6907045
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:6907045
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:5685014
RGD:6907045
G Map3k8 mitogen-activated protein kinase kinase kinase 8 JBrowse link 17 56,109,403 56,129,925 RGD:6907045
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6907045
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:6907045
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6907045
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:6907045
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:6907045
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6907045
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6907045
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6907045
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6907045
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:5685014
RGD:6907045
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6907045
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6907045
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:6907045
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta JBrowse link 8 107,275,849 107,381,088 RGD:6907045
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta JBrowse link 5 166,602,053 166,628,028 RGD:6907045
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:6907045
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 16 20,415,109 20,424,982 RGD:6907045
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 5 135,069,972 135,145,633 RGD:6907045
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 JBrowse link 10 55,013,686 55,078,986 RGD:6907045
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:6907045
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6907045
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:5685014
RGD:6907045
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6907045
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6907045
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 JBrowse link 7 121,350,953 121,382,100 RGD:5685016
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 JBrowse link 1 1,999,574 2,017,574 RGD:5685016
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 JBrowse link X 54,035,958 54,090,282 RGD:5685016
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:5685014
RGD:6907045
G Ticam2 toll-like receptor adaptor molecule 2 JBrowse link 18 40,555,106 40,572,569 RGD:5685014
RGD:6907045
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:5685014
RGD:6907045
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:1643119
RGD:5685014
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1643119
RGD:6907045
RGD:5685014
RGD:5684896
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1643119
RGD:6907045
RGD:5685014
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1643119
RGD:7247704
RGD:6907045
RGD:5685014
G Tlr5 toll-like receptor 5 JBrowse link 13 101,364,784 101,385,764 RGD:1643119
RGD:6907045
RGD:5685014
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1643119
RGD:6907045
RGD:5685014
RGD:5684896
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1643119
RGD:6907045
RGD:5685014
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1643119
RGD:6907045
RGD:5685014
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1643119
RGD:6907045
RGD:5685014
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6907045
G Tollip toll interacting protein JBrowse link 1 214,823,993 214,844,861 RGD:6907045
G Tradd TNFRSF1A-associated via death domain JBrowse link 19 37,214,461 37,221,099 RGD:5685014
G Traf3 Tnf receptor-associated factor 3 JBrowse link 6 135,610,698 135,720,247 RGD:5685014
RGD:6907045
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:5685014
RGD:6907045
G Ube2n ubiquitin-conjugating enzyme E2N JBrowse link 7 36,610,147 36,640,190 RGD:5685014
G Ube2v1 ubiquitin conjugating enzyme E2 V1 JBrowse link 3 164,343,833 164,366,684 RGD:5685014
G Unc93b1 unc-93 homolog B1, TLR signaling regulator JBrowse link 1 219,172,987 219,183,941 RGD:5685014
tumor necrosis factor mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:2292150
RGD:6484113
G Bag4 BAG cochaperone 4 JBrowse link 16 71,057,709 71,075,874 RGD:2292150
RGD:6484113
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:6484113
RGD:7800730
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:6484113
RGD:7800730
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6484113
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:6484113
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:2292150
RGD:6484113
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:6484113
RGD:7800735
RGD:7800734
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:2292150
RGD:6484113
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:2292150
RGD:6484113
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:2292150
RGD:6484113
G Itch itchy E3 ubiquitin protein ligase JBrowse link 3 150,660,665 150,752,016 RGD:7800734
RGD:7800735
G Madd MAP-kinase activating death domain JBrowse link 3 79,960,301 80,003,023 RGD:6484113
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:6484113
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:6484113
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:6484113
G Map3k3 mitogen activated protein kinase kinase kinase 3 JBrowse link 10 94,280,703 94,349,372 RGD:6484113
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:6484113
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:6484113
RGD:5490225
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 JBrowse link 1 221,710,622 221,726,274 RGD:6484113
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 JBrowse link 6 3,276,732 3,444,519 RGD:6484113
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 JBrowse link 9 46,657,444 46,782,545 RGD:6484113
G Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 JBrowse link 6 92,136,242 92,229,578 RGD:6484113
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6484113
G Nrk Nik related kinase JBrowse link X
X
109,940,439
110,065,199
110,036,361
110,089,124
RGD:6484113
G Nsmaf neutral sphingomyelinase activation associated factor JBrowse link 5 19,499,111 19,560,308 RGD:6484113
G Prkci protein kinase C, iota JBrowse link 2 115,941,998 116,002,550 RGD:6484113
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:6484113
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:6484113
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 JBrowse link 3 147,793,014 147,809,941 RGD:7800730
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6484113
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase JBrowse link 10 70,157,621 70,220,618 RGD:6484113
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:2292150
RGD:7800730
RGD:6484113
G Rnf11 ring finger protein 11 JBrowse link 5 129,296,271 129,298,513 RGD:7800734
RGD:7800735
G Rnf31 ring finger protein 31 JBrowse link 15 34,270,037 34,282,385 RGD:7800730
G Sharpin SHANK-associated RH domain interactor JBrowse link 7 117,413,151 117,417,455 RGD:7800730
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:6484113
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link 20 46,212,070 46,215,183 RGD:6484113
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6484113
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6484113
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 JBrowse link 7 121,350,953 121,382,100 RGD:6484113
RGD:5490225
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 JBrowse link 1 1,999,574 2,017,574 RGD:6484113
RGD:5490225
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 JBrowse link X 54,035,958 54,090,282 RGD:5490225
G Tax1bp1 Tax1 binding protein 1 JBrowse link 4 82,776,720 82,832,586 RGD:7800734
RGD:7800735
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1580210
RGD:6484113
RGD:2292150
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:7800734
RGD:7800735
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:2292150
RGD:6484113
RGD:5130945
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:2292150
RGD:6484113
G Tnik TRAF2 and NCK interacting kinase JBrowse link 2 113,984,599 114,391,805 RGD:6484113
G Tradd TNFRSF1A-associated via death domain JBrowse link 19 37,214,461 37,221,099 RGD:2292150
RGD:6484113
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:2292150
RGD:7800730
RGD:6484113
RGD:5130945
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:6484113

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6016
    regulatory pathway 3823
      immune response pathway 538
        innate immune response pathway 294
          complement system pathway + 71
          inflammatory response pathway + 226
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.