PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: nicotinamide adenine dinucleotide biosynthetic pathway
Accession: PW:0000219
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Definition: Those metabolic reactions involved in the synthesis of nicotinamide adenine dinucleotide (NAD). NAD can be synthesized de novo downstream of kynurenine metabolism of tryptophan degradation, or from precursors such as nicotinamide, nicotinic acid or nicotinamide riboside, collectively known as vitamin B3 or niacin.
Synonyms: exact_synonym: NAD biosynthetic pathway
related_synonym: NAD biosynthetic process
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NADSYN1
NAD synthetase 1
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr 1:3,189,054...3,243,087
Ensembl chr 1:3,188,348...3,238,435
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NMNAT1
nicotinamide nucleotide adenylyltransferase 1
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr20:121,790,836...121,797,043
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NMNAT2
nicotinamide nucleotide adenylyltransferase 2
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr25:45,954,934...46,130,106
Ensembl chr25:45,954,862...46,125,378
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NMNAT3
nicotinamide nucleotide adenylyltransferase 3
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr15:50,880,146...50,990,958
Ensembl chr15:50,880,235...50,991,281
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QPRT
quinolinate phosphoribosyltransferase
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr 5:26,953,980...26,970,120
Ensembl chr 5:26,950,391...26,970,079
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NADSYN1
NAD synthetase 1
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr 1:3,189,054...3,243,087
Ensembl chr 1:3,188,348...3,238,435
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NAMPT
nicotinamide phosphoribosyltransferase
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr21:75,160,748...75,195,781
Ensembl chr21:75,158,596...75,196,025
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NAPRT
nicotinate phosphoribosyltransferase
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr 8:137,794,933...137,799,145
Ensembl chr 8:137,792,993...137,798,658
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NMNAT1
nicotinamide nucleotide adenylyltransferase 1
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr20:121,790,836...121,797,043
G
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr25:45,954,934...46,130,106
Ensembl chr25:45,954,862...46,125,378
G
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr15:50,880,146...50,990,958
Ensembl chr15:50,880,235...50,991,281
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NMRK1
nicotinamide riboside kinase 1
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr12:86,112,583...86,140,457
Ensembl chr12:86,112,271...86,140,449
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NMRK2
nicotinamide riboside kinase 2
ISO
RGD
PMID:20007326
RGD:11099972
NCBI chr 6:3,685,337...3,697,868
Ensembl chr 6:3,688,166...3,697,960
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