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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:p38 MAPK signaling pathway
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Accession:PW:0000198 term browser browse the term
Definition:A SAPK MAPK pathway that plays an important role in inflammation and may be involved in several forms of cancer.
Synonyms:related_synonym: p38MAPK events
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p38 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IMP RGD PMID:16157033 RGD:1625329 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Atm ATM serine/threonine kinase ISO PID PID:200018 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Bnip2 BCL2 interacting protein 2 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590 		JBrowse link
G Calm1 calmodulin 1 ISO PID PID:200018 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 ISO PID PID:200018 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 ISO PID PID:200018 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO PID PID:200018 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Ccm2 CCM2 scaffold protein ISO PID
RGD		 PMID:17481747 PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Cdc42 cell division cycle 42 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:20626350 RGD:7240533 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Dusp9 dual specificity phosphatase 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO PID PID:200018 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta ISO PID PID:200018 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma ISO PID PID:200018 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:15141302 RGD:5128786 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 ISO
IDA		 PID
RGD		 PMID:17481747 PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO
IDA		 PID
RGD		 PMID:17481747 PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200018 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO PID PID:200018 NCBI chr 1:82,955,784...82,974,084
Ensembl chr 1:82,955,207...82,974,084 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO PID
RGD		 PMID:17481747 PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 ISO PID PID:200018 NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO
IDA		 PID
RGD		 PMID:17481747 PMID:16183734 PMID:20626350 PID:200018, RGD:2293891, RGD:2298758, RGD:7240533 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO RGD PMID:20626350 RGD:7240533 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO PID
RGD		 PMID:17481747 PID:200018, RGD:2293891 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 ISO RGD PMID:17481747 RGD:2293891 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 ISO RGD PMID:17481747 RGD:2293891 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 IDA
ISO		 PID
RGD		 PMID:16407200 PMID:17481747 PID:200018, RGD:1580544, RGD:2293891 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO
IMP		 RGD PMID:17481747 PMID:12024021 RGD:2293891, RGD:2302280 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO PID
RGD		 PMID:17481747 PID:200018, RGD:2293891 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:204,021,805...204,032,781
Ensembl chr 1:204,021,806...204,032,761 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224 		JBrowse link
G Spag9 sperm associated antigen 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO PID PID:200018 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO PID PID:200018 NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756 		JBrowse link
G Taok1 TAO kinase 1 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Taok2 TAO kinase 2 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Taok3 TAO kinase 3 ISO PID PID:200018 NCBI chr12:39,312,354...39,473,656
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO PID
RGD		 PMID:12215209 PID:200018, RGD:2296020 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 ISO PID
RGD		 PMID:20626350 PID:200018, RGD:7240533 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Txn1 thioredoxin 1 ISO PID PID:200018 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      mitogen activated protein kinase signaling pathway 299
        stress-regulated MAPK signaling pathway 70
          p38 MAPK signaling pathway 54
            altered p38 MAPK signaling pathway 0
Path 2
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      kinase mediated signaling pathway 601
        serine/threonine-specific kinase mediated signaling pathway 475
          mitogen activated protein kinase signaling pathway 299
            stress-regulated MAPK signaling pathway 70
              p38 MAPK signaling pathway 54
                altered p38 MAPK signaling pathway 0
paths to the root