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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:porphyrin and chlorophyll metabolic pathway
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Accession:PW:0000190 term browser browse the term
Definition:Those reactions involved in the synthesis, utilization and/or degradation of porphyrin - any of a group of compounds containing the porphyrin structure, four pyrrole rings connected by methine bridges in a cyclic configuration, to which a variety of side chains may be attached - and chlorophyll - any of a group of green magnesium-containing porphyrin derivatives occurring in all photosynthetic organisms.
Synonyms:related_synonym: KEGG:00860


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porphyrin and chlorophyll metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase IEA KEGG rno:00860 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 IEA KEGG rno:00860 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 IEA KEGG rno:00860 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Blvra biliverdin reductase A IEA KEGG rno:00860 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
G Blvrb biliverdin reductase B IEA KEGG rno:00860 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 IEA KEGG rno:00860 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261 		JBrowse link
G Cp ceruloplasmin IEA KEGG rno:00860 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpox coproporphyrinogen oxidase IEA KEGG rno:00860 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial IEA KEGG rno:00860 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 IEA KEGG rno:00860 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966 		JBrowse link
G Fech ferrochelatase IEA KEGG rno:00860 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Fth1 ferritin heavy chain 1 IEA KEGG rno:00860 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 IEA KEGG rno:00860 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725 		JBrowse link
G Ftmt ferritin mitochondrial IEA KEGG rno:00860 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123 		JBrowse link
G Gusb glucuronidase, beta IEA KEGG rno:00860 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G Hccs holocytochrome c synthase IEA KEGG rno:00860 NCBI chr  X:24,932,943...24,942,376
Ensembl chr  X:24,933,002...24,942,366 		JBrowse link
G Hmbs hydroxymethylbilane synthase IEA KEGG rno:00860 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmox1 heme oxygenase 1 IEA KEGG rno:00860 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hmox2 heme oxygenase 2 IEA KEGG rno:00860 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148 		JBrowse link
G Ppox protoporphyrinogen oxidase IEA KEGG rno:00860 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IEA KEGG rno:00860 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 IEA KEGG rno:00860 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 IEA KEGG rno:00860 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 IEA KEGG rno:00860 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 IEA KEGG rno:00860 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C IEA KEGG rno:00860 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 IEA KEGG rno:00860 NCBI chr 9:88,727,094...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 IEA KEGG rno:00860 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 IEA KEGG rno:00860 NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531 		JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 IEA KEGG rno:00860 NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,572,808...20,590,729 		JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B IEA KEGG rno:00860 NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IEA KEGG rno:00860 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 IEA KEGG rno:00860 NCBI chr14:20,817,285...20,833,917
Ensembl chr14:20,817,285...20,833,917 		JBrowse link
G Urod uroporphyrinogen decarboxylase IEA KEGG rno:00860 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase IEA KEGG rno:00860 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
heme biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase IEA
ISO		 RGD PMID: PMID:26785297 PMID:16839620 RGD:1578396, RGD:11554188, RGD:4144542 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 IEA
ISO
IDA		 RGD PMID: PMID:26785297 PMID:16839620 PMID:16125296 RGD:1578396, RGD:11554188, RGD:4144542, RGD:1601233 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 IEA
ISO		 RGD PMID: PMID:26785297 PMID:16839620 RGD:1578396, RGD:11554188, RGD:4144542 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Cpox coproporphyrinogen oxidase IEA
ISO		 RGD PMID: PMID:26785297 PMID:16839620 RGD:1578396, RGD:11554188, RGD:4144542 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Fech ferrochelatase IEA
ISO		 RGD PMID: PMID:26785297 PMID:16839620 RGD:1578396, RGD:11554188, RGD:4144542 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hmbs hydroxymethylbilane synthase IEA
IDA
IMP
ISO		 RGD PMID: PMID:593266 PMID:6694518 PMID:1781034 PMID:6893114 More... RGD:1578396, RGD:26884337, RGD:25330343, RGD:25440495, RGD:26923963, RGD:11554188, RGD:4144542, RGD:2301704 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Ppox protoporphyrinogen oxidase IEA
ISO
IDA		 RGD PMID: PMID:26785297 PMID:16839620 PMID:3663105 RGD:1578396, RGD:11554188, RGD:4144542, RGD:1599180 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Slc25a38 solute carrier family 25, member 38 ISO RGD PMID:26785297 PMID:27476175 RGD:11554188, RGD:11556278 NCBI chr 8:119,835,546...119,848,334
Ensembl chr 8:119,835,634...119,848,332 		JBrowse link
G Tspo translocator protein ISO RGD PMID:26785297 RGD:11554188 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Urod uroporphyrinogen decarboxylase IEA
ISO
IDA		 RGD PMID: PMID:26785297 PMID:16839620 PMID:10416273 RGD:1578396, RGD:11554188, RGD:4144542, RGD:2303399 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase IEA
ISO
TAS		 RGD PMID: PMID:26785297 PMID:3327431 PMID:16839620 RGD:1578396, RGD:11554188, RGD:4144823, RGD:4144542 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
heme degradation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 IDA RGD PMID:15226268 RGD:1547877 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
porphyrin metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase ISO SMPDB SMP:00024 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 ISO SMPDB SMP:00024 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Blvra biliverdin reductase A ISO SMPDB SMP:00024 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 ISO SMPDB SMP:00024 NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667 		JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 ISO SMPDB SMP:00024 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261 		JBrowse link
G Cpox coproporphyrinogen oxidase ISO SMPDB SMP:00024 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Fech ferrochelatase ISO SMPDB SMP:00024 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Ftmt ferritin mitochondrial ISO SMPDB SMP:00024 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123 		JBrowse link
G Gusb glucuronidase, beta ISO SMPDB SMP:00024 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G Hmbs hydroxymethylbilane synthase ISO SMPDB SMP:00024 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmox1 heme oxygenase 1 ISO SMPDB SMP:00024 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ppox protoporphyrinogen oxidase ISO SMPDB SMP:00024 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Urod uroporphyrinogen decarboxylase ISO SMPDB SMP:00024 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Uros uroporphyrinogen III synthase ISO SMPDB SMP:00024 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      metabolic pathway of cofactors, vitamins, nutrients 367
        porphyrin and chlorophyll metabolic pathway 38
          porphyrin metabolic pathway + 17
paths to the root