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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:nerve growth factor signaling pathway
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Accession:PW:0000169 term browser browse the term
Definition:Nerve growth factor (NGF) signaling pathways control a variety of processes such as neuronal cell differentiation and axon growth. Members of the NGF family are best known for their anti-apoptotic role as mediators of neuronal cell survival.
Synonyms:related_synonym: NGF signaling pathway



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nerve growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IMP RGD PMID:15728722 RGD:1581104 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IDA RGD PMID:15546918 RGD:1580675 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link

Term paths to the root
Path 1
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  pathway 6092
    signaling pathway 2646
      growth factor signaling pathway 523
        neurotrophic factor signaling pathway 128
          nerve growth factor signaling pathway 2
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