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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:growth factor signaling pathway
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Accession:PW:0000168 term browser browse the term
Definition:Those pathways that are triggered through the binding of a growth factor to its particular receptor. Growth factors carry out mitogenic signaling via their largely tyrosine kinase receptors.


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activin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 ISO PID
RGD		 PMID:12770730 PID:200029 RGD:1559169 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVR1B activin A receptor type 1B ISO RGD PMID:12770730 PMID:17040568 RGD:1559169 RGD:2315948 NCBI chr27:3,009,710...3,029,726
Ensembl chr27:2,994,857...3,042,396 		JBrowse link
G ACVR2A activin A receptor type 2A ISO RGD PMID:12770730 RGD:1559169 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVR2B activin A receptor type 2B ISO RGD PMID:12770730 RGD:1559169 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894 		JBrowse link
G ACVRL1 activin A receptor like type 1 ISO PID
RGD		 PMID:12770730 PID:200029 RGD:1559169 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO PID PID:200029 NCBI chr24:19,618,581...19,643,685
Ensembl chr24:19,618,558...19,643,046 		JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:12770730 RGD:1559169 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 ISO RGD PMID:12770730 RGD:1559169 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
altered epidermal growth factor/neuregulin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGF epidermal growth factor ISO RGD PMID:19506583 RGD:5490965 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295 		JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:19506583 PMID:20519133 PMID:20951313 RGD:5133241 RGD:5133242 RGD:5490965 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:19078924 PMID:21277552 RGD:4143515 RGD:5133243 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294 		JBrowse link
G TGFA transforming growth factor alpha ISO RGD PMID:19506583 RGD:5490965 NCBI chr10:68,915,671...68,957,027 JBrowse link
altered insulin-like growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1 insulin like growth factor 1 ISO RGD PMID:15996002 RGD:1580474 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
altered scatter factor/hepatocyte growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MET MET proto-oncogene, receptor tyrosine kinase ISO RGD PMID:19506583 PMID:20519133 PMID:20951313 PMID:21277552 RGD:5133241 RGD:5133242 RGD:5133243 RGD:5490965 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
altered transforming growth factor-beta Smad dependent signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 ISO RGD PMID:17613544 PMID:18313409 RGD:2299005 RGD:2306282 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:17613544 PMID:18662538 RGD:2306282 RGD:2308865 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 ISO RGD PMID:17613544 PMID:18772397 RGD:2306282 RGD:5490966 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SMAD4 SMAD family member 4 ISO RGD PMID:17613544 PMID:18662538 PMID:18772397 PMID:19506583 RGD:2306282 RGD:2308865 RGD:5490965 RGD:5490966 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD7 SMAD family member 7 ISO RGD PMID:18662538 RGD:2308865 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD PMID:17613544 PMID:18313409 RGD:2299005 RGD:2306282 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO RGD PMID:17613544 PMID:18313409 PMID:18662538 PMID:18772397 PMID:19506583 RGD:2299005 RGD:2306282 RGD:2308865 RGD:5490965 RGD:5490966 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
altered vascular endothelial growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT4 fms related receptor tyrosine kinase 4 ISO RGD PMID:15563310 RGD:1334463 NCBI chr11:1,145,643...1,184,097
Ensembl chr11:1,145,585...1,185,165 		JBrowse link
altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDR kinase insert domain receptor ISO RGD PMID:18221855 RGD:2292019 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:18221855 RGD:2292019 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
altered vascular endothelial growth factor signaling pathway involving the main players term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT4 fms related receptor tyrosine kinase 4 ISO RGD PMID:15563310 RGD:1334463 NCBI chr11:1,145,643...1,184,097
Ensembl chr11:1,145,585...1,185,165 		JBrowse link
G KDR kinase insert domain receptor ISO RGD PMID:18221855 RGD:2292019 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:18221855 RGD:2292019 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
angiopoietin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 ISO RGD PMID:15714275 RGD:1578337 NCBI chr13:8,068,920...8,312,090
Ensembl chr13:8,048,205...8,311,618 		JBrowse link
G TEK TEK receptor tyrosine kinase ISO RGD PMID:15714275 RGD:1578337 NCBI chr11:45,278,375...45,377,300
Ensembl chr11:45,278,891...45,409,093 		JBrowse link
Bone morphogenetic proteins signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein ISO PID PID:200144 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor ISO PID PID:200144 NCBI chr 2:17,453,628...17,459,812
Ensembl chr 2:17,455,243...17,462,346 		JBrowse link
G BMP2 bone morphogenetic protein 2 ISO PID
RGD		 PMID:16361357 PID:200144 RGD:1580077 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP4 bone morphogenetic protein 4 ISO PID
RGD		 PMID:18985159 PID:200144 RGD:11553861 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO PID PID:200144 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G BMP7 bone morphogenetic protein 7 ISO PID PID:200144 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A ISO PID PID:200144 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B ISO PID PID:200144 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO RGD
PID		 PMID:16361357 PID:200144 RGD:1580077 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist ISO PID PID:200144 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G CHRD chordin ISO PID PID:200144 NCBI chr34:17,255,770...17,264,776
Ensembl chr34:17,255,562...17,271,713 		JBrowse link
G CHRDL1 chordin like 1 ISO PID PID:200144 NCBI chr  X:83,816,131...83,936,497
Ensembl chr  X:83,817,880...83,936,949 		JBrowse link
G CTDSP1 CTD small phosphatase 1 ISO PID PID:200144 NCBI chr37:25,051,839...25,057,506
Ensembl chr37:25,050,267...25,056,113 		JBrowse link
G CTDSP2 CTD small phosphatase 2 ISO PID PID:200144 NCBI chr10:1,875,307...1,898,385
Ensembl chr10:1,876,536...1,898,348 		JBrowse link
G CTDSPL CTD small phosphatase like ISO PID PID:200144 NCBI chr23:7,616,264...7,760,595
Ensembl chr23:7,725,446...7,758,067 		JBrowse link
G FST follistatin ISO PID PID:200144 NCBI chr 4:61,779,252...61,785,666
Ensembl chr 4:61,779,259...61,783,260 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist ISO PID PID:200144 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO PID PID:200144 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
G HJV hemojuvelin BMP co-receptor ISO PID PID:200144 NCBI chr17:58,792,647...58,797,504
Ensembl chr17:58,793,247...58,797,373 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO PID PID:200144 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200144 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G NOG noggin ISO PID PID:200144 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G NUP214 nucleoporin 214 ISO PID PID:200144 NCBI chr 9:52,840,300...52,943,785
Ensembl chr 9:52,841,096...52,947,770 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A ISO PID PID:200144 NCBI chr 8:35,336,055...35,384,249
Ensembl chr 8:35,336,140...35,377,551 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO PID PID:200144 NCBI chr18:50,062,352...50,065,166
Ensembl chr18:50,062,352...50,065,166 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO PID PID:200144 NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a ISO PID PID:200144 NCBI chr 3:47,044,342...47,089,923
Ensembl chr 3:47,061,910...47,089,294 		JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b ISO PID PID:200144 NCBI chr 3:11,407,426...11,427,317 JBrowse link
G SKI SKI proto-oncogene ISO PID PID:200144 NCBI chr 5:57,144,178...57,216,385
Ensembl chr 5:57,145,825...57,214,403 		JBrowse link
G SLC39A13 solute carrier family 39 member 13 ISO RGD PMID:18985159 RGD:11553861 NCBI chr18:42,221,311...42,229,992
Ensembl chr18:42,222,333...42,227,361 		JBrowse link
G SMAD1 SMAD family member 1 ISO RGD
PID		 PMID:16361357 PMID:18985159 PID:200144 RGD:11553861 RGD:1580077 NCBI chr15:44,093,491...44,171,177
Ensembl chr15:44,095,497...44,170,098 		JBrowse link
G SMAD4 SMAD family member 4 ISO PID PID:200144 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD5 SMAD family member 5 ISO RGD
PID		 PMID:16361357 PMID:18985159 PID:200144 RGD:11553861 RGD:1580077 NCBI chr11:24,027,603...24,082,673
Ensembl chr11:24,028,126...24,078,169 		JBrowse link
G SMAD6 SMAD family member 6 ISO PID PID:200144 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 ISO PID PID:200144 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMAD9 SMAD family member 9 ISO PID
RGD		 PMID:16361357 PID:200144 RGD:1580077 NCBI chr25:3,768,851...3,844,645
Ensembl chr25:3,779,197...3,841,321 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 ISO PID PID:200144 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 ISO PID PID:200144 NCBI chr 9:12,348,777...12,472,636
Ensembl chr 9:12,351,627...12,471,467 		JBrowse link
G SOSTDC1 sclerostin domain containing 1 ISO PID PID:200144 NCBI chr14:31,035,759...31,079,139
Ensembl chr14:31,022,766...31,026,737
Ensembl chr14:31,022,766...31,026,737 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO PID PID:200144 NCBI chr10:25,623,381...25,657,630
Ensembl chr10:25,623,940...25,657,543 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO PID PID:200144 NCBI chr 1:40,125,842...40,216,455
Ensembl chr 1:40,149,569...40,215,385 		JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO PID PID:200144 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
G ZFYVE16 zinc finger FYVE-type containing 16 ISO PID PID:200144 NCBI chr 3:26,662,750...26,714,184
Ensembl chr 3:26,664,068...26,699,073 		JBrowse link
brain-derived neurotrophic factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor ISO RGD PMID:23670594 RGD:11062158 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr10:11,445,843...11,552,325
Ensembl chr10:11,539,994...11,552,890 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 1:74,447,927...74,777,910
Ensembl chr 1:74,449,060...74,777,032 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:23670594 RGD:11062158 NCBI chr31:26,058,858...26,440,059
Ensembl chr31:25,932,697...26,202,756 		JBrowse link
epidermal growth factor/neuregulin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 ISO RGD PMID:15688065 RGD:2317976 NCBI chr30:23,605,724...23,732,038
Ensembl chr30:23,606,517...23,731,823 		JBrowse link
G ADAM12 ADAM metallopeptidase domain 12 ISO RGD PMID:15688065 RGD:2317976 NCBI chr28:35,154,899...35,484,852
Ensembl chr28:35,158,126...35,485,573 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 ISO RGD PMID:15688065 RGD:2317976 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 ISO RGD PMID:15688065 RGD:2317976 NCBI chr 4:52,650,077...52,733,299
Ensembl chr 4:52,650,162...52,729,843 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 ISO RGD PMID:15688065 RGD:2317976 NCBI chr16:26,413,345...26,551,293
Ensembl chr16:26,414,583...26,551,122 		JBrowse link
G AREG amphiregulin ISO PID
RGD		 PMID:15509566 PMID:15982853 PID:200159 RGD:1578718 RGD:2317963 NCBI chr13:62,925,761...62,936,753
Ensembl chr13:62,926,301...62,936,738 		JBrowse link
G BTC betacellulin ISO RGD
PID		 PMID:11564606 PMID:15982853 PID:200159 RGD:2317963 RGD:2324625 NCBI chr15:64,133,051...64,159,155
Ensembl chr15:64,135,920...64,158,970 		JBrowse link
G CBL Cbl proto-oncogene ISO RGD PMID:16829981 RGD:2317988 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G EGF epidermal growth factor ISO PID
RGD		 PMID:2260661 PMID:15982853 PID:200101 PID:200159 RGD:1626483 RGD:2317963 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295 		JBrowse link
G EGFR epidermal growth factor receptor ISO RGD
PID		 PMID:15486316 PMID:15982853 PMID:16648628 PID:200101 PID:200159 RGD:1581898 RGD:1581908 RGD:2317963 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G EPGN epithelial mitogen ISO RGD PMID:15982853 RGD:2317963 NCBI chr13:62,803,595...62,811,581
Ensembl chr13:62,803,654...62,810,274 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO PID
RGD		 PMID:15982853 PID:200159 RGD:2317963 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO Neuregulin stimulation of glucose transport in muscle cells RGD
PID		 PMID:14711829 PMID:15007074 PMID:16829981 PMID:18519747 PID:200159 RGD:1642700 RGD:2289958 RGD:2317965 RGD:2317988 NCBI chr10:406,856...424,746
Ensembl chr10:406,633...424,264 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:18519747 RGD:2317965 NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426 		JBrowse link
G EREG epiregulin ISO PID
RGD		 PMID:15982853 PID:200159 RGD:2317963 NCBI chr13:62,857,325...62,877,831
Ensembl chr13:62,856,709...62,877,760 		JBrowse link
G GAB1 GRB2 associated binding protein 1 ISO PID PID:200101 NCBI chr19:10,269...117,808
Ensembl chr19:12,616...156,694 		JBrowse link
G GNAI1 G protein subunit alpha i1 ISO PID PID:200101 NCBI chr18:19,924,381...19,952,956
Ensembl chr18:19,924,235...19,951,244 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO PID PID:200101 NCBI chr 6:42,275,060...42,315,545
Ensembl chr 6:42,276,998...42,315,533 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 ISO RGD PMID:20445128 RGD:4892084 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID
RGD		 PMID:16829981 PID:200101 RGD:2317988 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G GSN gelsolin ISO PID PID:200101 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G HBEGF heparin binding EGF like growth factor ISO RGD
PID		 PMID:15486316 PMID:15982853 PID:200159 RGD:1581908 RGD:2317963 NCBI chr 2:35,551,248...35,563,310
Ensembl chr 2:35,551,250...35,563,043 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO PID PID:200101 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO PID PID:200159 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243 		JBrowse link
G LOC100856339 phosphatidylinositol 3-kinase regulatory subunit gamma ISO PID PID:200101 NCBI chr15:14,222,059...14,357,200
Ensembl chr15:14,235,824...14,353,832 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200101 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO PID PID:200101 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G NCK1 NCK adaptor protein 1 ISO PID PID:200101 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534 		JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200101 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO PID PID:200101 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G NRG1 neuregulin 1 ISO RGD PMID:18519747 RGD:2317965 NCBI chr16:31,697,958...32,771,888
Ensembl chr16:31,706,851...32,771,932 		JBrowse link
G NRG2 neuregulin 2 ISO RGD
PID		 PMID:9348101 PMID:18519747 PID:200159 RGD:1304015 RGD:2317965 NCBI chr 2:35,085,192...35,264,509
Ensembl chr 2:35,085,361...35,264,378 		JBrowse link
G NRG3 neuregulin 3 ISO PID
RGD		 PMID:18519747 PID:200159 RGD:2317965 NCBI chr 4:30,515,845...31,557,598
Ensembl chr 4:30,515,890...31,556,152 		JBrowse link
G NRG4 neuregulin 4 ISO PID
RGD		 PMID:18519747 PID:200159 RGD:2317965 NCBI chr29:7,478,483...7,483,875 JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO PID PID:200101 NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 ISO Neuregulin stimulation of glucose transport in muscle cells RGD PMID:15007074 RGD:1642700 NCBI chr36:16,918,329...16,944,532
Ensembl chr36:16,918,058...16,944,620 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200101 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO PID PID:200101 NCBI chr23:34,832,661...34,955,410
Ensembl chr23:34,836,540...34,993,939 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO PID PID:200101 NCBI chr 5:62,884,596...62,936,882
Ensembl chr 5:62,909,009...62,935,971 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID
RGD		 PMID:16829981 PID:200101 RGD:2317988 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 ISO PID PID:200101 NCBI chr20:44,826,037...44,838,449
Ensembl chr20:44,826,339...44,836,558 		JBrowse link
G PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma ISO PID PID:200101 NCBI chr20:55,751,055...55,801,740
Ensembl chr20:55,751,158...55,799,160 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO PID PID:200101 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PRKCZ protein kinase C zeta ISO Neuregulin stimulation of glucose transport in muscle cells RGD PMID:15007074 RGD:1642700 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO PID PID:200101 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200101 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO PID PID:200101 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO RGD PMID:16829981 RGD:2317988 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO PID PID:200101 NCBI chr 3:21,068,182...21,177,288
Ensembl chr 3:21,054,930...21,176,757 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO RGD PMID:16829981 RGD:2317988 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID
RGD		 PMID:8577724 PMID:16829981 PID:200101 RGD:1581110 RGD:2317988 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 ISO RGD PMID:16829981 RGD:2317988 NCBI chr 8:26,636,849...26,698,837
Ensembl chr 8:26,637,895...26,717,781 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO PID
RGD		 PMID:15856020 PID:200101 RGD:1581134 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO PID PID:200101 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO PID PID:200101 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TGFA transforming growth factor alpha ISO PID
RGD		 PMID:15982853 PID:200159 RGD:2317963 NCBI chr10:68,915,671...68,957,027 JBrowse link
G TLN1 talin 1 ISO PID PID:200101 NCBI chr11:52,227,286...52,260,112
Ensembl chr11:52,227,611...52,259,915 		JBrowse link
G WASL WASP like actin nucleation promoting factor ISO PID PID:200101 NCBI chr14:11,828,298...11,901,190
Ensembl chr14:11,828,687...11,899,788 		JBrowse link
fibroblast growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200220 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO PID PID:200220 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO PID PID:200220 NCBI chr 4:58,800,818...58,865,830
Ensembl chr 4:58,800,813...58,865,830 		JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200220 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G CDH1 cadherin 1 ISO PID PID:200220 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878 		JBrowse link
G CDH2 cadherin 2 ISO PID PID:200220 NCBI chr 7:60,736,760...60,950,477
Ensembl chr 7:60,736,760...60,951,034 		JBrowse link
G CTNND1 catenin delta 1 ISO PID PID:200220 NCBI chr18:38,415,687...38,469,777
Ensembl chr18:38,417,701...38,462,216 		JBrowse link
G CTTN cortactin ISO PID PID:200220 NCBI chr18:47,932,367...47,960,732
Ensembl chr18:47,916,632...47,960,674 		JBrowse link
G FGF1 fibroblast growth factor 1 ISO PID PID:200220 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619 		JBrowse link
G FGF17 fibroblast growth factor 17 ISO PID PID:200220 NCBI chr25:35,194,400...35,204,787
Ensembl chr25:35,194,394...35,199,792 		JBrowse link
G FGF18 fibroblast growth factor 18 ISO PID PID:200220 NCBI chr 4:40,714,891...40,748,892
Ensembl chr 4:40,715,060...40,748,518 		JBrowse link
G FGF19 fibroblast growth factor 19 ISO PID PID:200220 NCBI chr18:48,464,931...48,469,967
Ensembl chr18:48,464,928...48,469,782 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO PID PID:200220 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G FGF23 fibroblast growth factor 23 ISO PID PID:200220 NCBI chr27:40,501,655...40,511,785
Ensembl chr27:40,501,731...40,509,766 		JBrowse link
G FGF4 fibroblast growth factor 4 ISO PID PID:200220 NCBI chr18:48,413,480...48,417,494
Ensembl chr18:48,413,187...48,416,977 		JBrowse link
G FGF6 fibroblast growth factor 6 ISO PID PID:200220 NCBI chr27:40,440,298...40,456,933
Ensembl chr27:40,440,377...40,455,257 		JBrowse link
G FGF8 fibroblast growth factor 8 ISO PID PID:200220 NCBI chr28:14,362,407...14,367,109
Ensembl chr28:14,362,109...14,367,468 		JBrowse link
G FGF9 fibroblast growth factor 9 ISO RGD
PID		 PMID:15231666 PID:200220 RGD:1304345 NCBI chr25:16,630,321...16,665,935
Ensembl chr25:16,632,812...16,663,550 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO PID PID:200220 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO RGD
PID		 PMID:15292181 PID:200220 RGD:2289848 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO RGD PMID:15231666 RGD:1304345 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 ISO PID PID:200220 NCBI chr 4:36,243,689...36,254,636
Ensembl chr 4:36,244,220...36,252,035 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200220 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 ISO PID PID:200220 NCBI chr10:11,445,843...11,552,325
Ensembl chr10:11,539,994...11,552,890 		JBrowse link
G GAB1 GRB2 associated binding protein 1 ISO PID PID:200220 NCBI chr19:10,269...117,808
Ensembl chr19:12,616...156,694 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID PID:200220 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G HGF hepatocyte growth factor ISO PID PID:200220 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263 		JBrowse link
G IL17RD interleukin 17 receptor D ISO PID PID:200220 NCBI chr20:33,240,728...33,306,727
Ensembl chr20:33,240,767...33,303,404 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200220 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G KL klotho ISO RGD PMID:16436388 RGD:1581599 NCBI chr25:7,154,359...7,201,744
Ensembl chr25:7,156,620...7,199,558 		JBrowse link
G KLB klotho beta ISO PID PID:200220 NCBI chr 3:72,996,725...73,033,566
Ensembl chr 3:72,998,816...73,033,651 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200220 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO PID PID:200220 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO PID PID:200220 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO PID PID:200220 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO PID PID:200220 NCBI chr 5:19,895,587...20,192,334
Ensembl chr 5:19,895,613...20,191,995 		JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 ISO PID PID:200220 NCBI chr 1:114,009,573...114,052,100
Ensembl chr 1:114,009,711...114,018,191 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200220 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200220 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200220 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PLAU plasminogen activator, urokinase ISO PID PID:200220 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO PID PID:200220 NCBI chr 1:111,476,804...111,490,876
Ensembl chr 1:111,476,893...111,490,880 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO PID PID:200220 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO PID PID:200220 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200220 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 ISO PID PID:200220 NCBI chr 2:73,497,128...73,533,853
Ensembl chr 2:73,497,473...73,534,378 		JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO PID PID:200220 NCBI chr12:13,723,535...13,842,565
Ensembl chr12:13,628,539...13,840,785
Ensembl chr12:13,628,539...13,840,785 		JBrowse link
G SDC2 syndecan 2 ISO PID PID:200220 NCBI chr29:40,939,498...41,026,694
Ensembl chr29:40,939,257...41,024,357 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO PID PID:200220 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID PID:200220 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO PID PID:200220 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 ISO PID PID:200220 NCBI chr22:33,366,139...33,371,102
Ensembl chr22:33,366,931...33,367,878 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200220 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G SSH1 slingshot protein phosphatase 1 ISO PID PID:200220 NCBI chr26:18,074,229...18,136,001
Ensembl chr26:18,074,075...18,131,185 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO PID PID:200220 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B ISO PID PID:200220 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485 		JBrowse link
Gas6 - Axl signaling axis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXL AXL receptor tyrosine kinase ISO RGD PMID:16285961 RGD:1579881 NCBI chr 1:112,699,679...112,727,434
Ensembl chr 1:112,700,365...112,726,960 		JBrowse link
G GAS6 growth arrest specific 6 ISO RGD PMID:16285961 RGD:1579881 NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875 		JBrowse link
insulin-like growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200100 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO PID PID:200100 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member ISO PID PID:200100 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO PID PID:200100 NCBI chr 9:45,594,657...45,627,499
Ensembl chr 9:45,598,899...45,627,589 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO PID PID:200100 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:20042609 RGD:7242068 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544 		JBrowse link
G GRB10 growth factor receptor bound protein 10 ISO PID PID:200100 NCBI chr18:1,890,689...2,014,836
Ensembl chr18:1,890,792...2,014,839 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO RGD
PID		 PMID:15272025 PID:200100 RGD:1581313 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO PID PID:200100 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G IGF1 insulin like growth factor 1 ISO RGD
PID		 PMID:7526037 PMID:15862547 PMID:16083987 PID:200100 RGD:12904768 RGD:1580473 RGD:1626333 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO PID
RGD		 PMID:15272025 PMID:15862547 PMID:20042609 PID:200100 RGD:1581313 RGD:1626333 RGD:7242068 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387 		JBrowse link
G IGF2 insulin like growth factor 2 ISO RGD PMID:15862547 RGD:1626333 NCBI chr18:46,294,036...46,311,982
Ensembl chr18:46,294,019...46,311,982 		JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO RGD PMID:15862547 RGD:1626333 NCBI chr 6:39,115,744...39,118,831
Ensembl chr 6:39,114,315...39,119,652 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO RGD PMID:15862547 RGD:1626333 NCBI chr16:1,037,169...1,040,996
Ensembl chr16:1,037,162...1,167,094 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO RGD PMID:15862547 RGD:1626333 NCBI chr37:23,553,227...23,569,321
Ensembl chr37:23,559,501...23,569,312 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:15862547 RGD:1626333 NCBI chr16:1,021,855...1,027,604
Ensembl chr16:1,021,972...1,026,392 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 ISO RGD PMID:15862547 RGD:1626333 NCBI chr 9:22,168,241...22,182,272
Ensembl chr 9:22,126,470...22,182,518 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 ISO RGD PMID:15862547 RGD:1626333 NCBI chr37:23,575,265...23,596,970
Ensembl chr37:23,579,841...23,596,870 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 ISO RGD PMID:15862547 RGD:1626333 NCBI chr27:2,063,548...2,067,366
Ensembl chr27:1,989,772...2,067,298 		JBrowse link
G IRS1 insulin receptor substrate 1 ISO PID
RGD		 PMID:15272025 PID:200100 RGD:1581313 NCBI chr25:39,624,554...39,687,991 JBrowse link
G IRS2 insulin receptor substrate 2 ISO PID PID:200100 NCBI chr22:58,197,016...58,229,026
Ensembl chr22:58,223,387...58,227,535 		JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200100 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200100 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200100 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200100 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PRKCD protein kinase C delta ISO PID PID:200100 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKCZ protein kinase C zeta ISO PID PID:200100 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G PRKD1 protein kinase D1 ISO PID PID:200100 NCBI chr 8:9,004,641...9,327,054
Ensembl chr 8:9,005,115...9,328,358 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO PID PID:200100 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200100 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G PXN paxillin ISO PID PID:200100 NCBI chr26:16,157,231...16,224,028
Ensembl chr26:16,159,025...16,184,820 		JBrowse link
G RACK1 receptor for activated C kinase 1 ISO PID PID:200100 NCBI chr11:426,734...431,087
Ensembl chr11:426,215...431,089 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO PID PID:200100 NCBI chr20:5,892,839...5,972,672
Ensembl chr20:5,892,834...5,972,090 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO PID PID:200100 NCBI chr 9:34,387,084...34,590,603
Ensembl chr 9:34,387,091...34,425,292 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO PID PID:200100 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID PID:200100 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon ISO PID PID:200100 NCBI chr 9:45,506,830...45,562,081
Ensembl chr 9:45,507,282...45,562,086 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO PID PID:200100 NCBI chr13:2,729,404...2,764,422 JBrowse link
nerve growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:15728722 RGD:1581104 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:15546918 RGD:1580675 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
platelet-derived growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI1 abl interactor 1 ISO PID PID:200149 NCBI chr 2:6,941,752...7,059,466
Ensembl chr 2:6,941,900...7,057,684 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO PID PID:200149 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle ISO PID PID:200149 NCBI chr26:38,700,434...38,714,915
Ensembl chr26:38,700,480...38,711,753 		JBrowse link
G ACTN4 actinin alpha 4 ISO PID PID:200149 NCBI chr 1:114,354,993...114,427,997
Ensembl chr 1:114,309,693...114,427,991 		JBrowse link
G ACTR2 actin related protein 2 ISO PID PID:200149 NCBI chr10:64,696,068...64,733,027
Ensembl chr10:64,696,111...64,730,553 		JBrowse link
G ACTR3 actin related protein 3 ISO PID PID:200149 NCBI chr19:35,097,968...35,133,330
Ensembl chr19:35,098,639...35,169,724 		JBrowse link
G AFDN afadin, adherens junction formation factor ISO PID PID:200149 NCBI chr 1:55,435,451...55,535,534
Ensembl chr 1:55,435,472...55,535,543 		JBrowse link
G ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ISO PID PID:200149 NCBI chr21:25,468,653...25,531,644
Ensembl chr21:25,443,386...25,531,165 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 ISO PID PID:200149 NCBI chr 1:108,952,836...109,034,329
Ensembl chr 1:108,952,562...109,034,337 		JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha ISO PID PID:200149 NCBI chr 9:419,350...422,284
Ensembl chr 9:419,413...423,252 		JBrowse link
G ARPC1B actin related protein 2/3 complex subunit 1B ISO PID PID:200149 NCBI chr 6:10,192,299...10,198,383
Ensembl chr 6:10,178,462...10,198,309 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO PID PID:200149 NCBI chr37:24,914,389...24,935,998
Ensembl chr37:24,914,642...24,935,824 		JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 ISO PID PID:200149 NCBI chr26:8,267,123...8,277,779
Ensembl chr26:8,267,196...8,277,688 		JBrowse link
G ARPC4 actin related protein 2/3 complex subunit 4 ISO PID PID:200149 NCBI chr20:8,441,994...8,453,131
Ensembl chr20:8,442,788...8,453,057 		JBrowse link
G ARPC5 actin related protein 2/3 complex subunit 5 ISO PID PID:200149 NCBI chr 7:16,976,392...16,986,015
Ensembl chr 7:16,977,555...16,985,943 		JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 ISO PID PID:200149 NCBI chr 9:923,519...992,254
Ensembl chr 9:923,493...981,923 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member ISO PID PID:200149 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase ISO PID PID:200149 NCBI chr25:26,336,253...26,357,494
Ensembl chr25:26,336,892...26,358,015 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO PID PID:200149 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex ISO PID PID:200149 NCBI chr20:8,220,109...8,231,337
Ensembl chr20:8,221,575...8,231,258 		JBrowse link
G CAV1 caveolin 1 ISO PID PID:200162 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G CAV3 caveolin 3 ISO PID PID:200162 NCBI chr20:9,384,901...9,398,055
Ensembl chr20:9,384,901...9,401,196 		JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200149 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO PID PID:200149 PID:200162 NCBI chr 9:45,594,657...45,627,499
Ensembl chr 9:45,598,899...45,627,589 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO PID PID:200162 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964 		JBrowse link
G CSK C-terminal Src kinase ISO PID PID:200149 NCBI chr30:37,851,269...37,870,382
Ensembl chr30:37,852,046...37,870,378 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO PID PID:200162 NCBI chr24:20,333,593...20,390,341 JBrowse link
G CTTN cortactin ISO PID PID:200149 NCBI chr18:47,932,367...47,960,732
Ensembl chr18:47,916,632...47,960,674 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 ISO PID PID:200149 NCBI chr 4:52,769,638...52,875,080
Ensembl chr 4:52,743,048...52,880,589 		JBrowse link
G DNM2 dynamin 2 ISO PID PID:200149 NCBI chr20:50,398,866...50,487,303
Ensembl chr20:50,398,864...50,487,241 		JBrowse link
G DOCK4 dedicator of cytokinesis 4 ISO PID PID:200149 NCBI chr14:51,448,910...51,859,366
Ensembl chr14:51,451,059...51,859,040 		JBrowse link
G DOK1 docking protein 1 ISO PID PID:200149 NCBI chr17:48,588,579...48,591,523
Ensembl chr17:48,589,023...48,591,721 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 ISO PID PID:200149 NCBI chr17:29,494,641...29,537,933
Ensembl chr17:29,496,128...29,537,933 		JBrowse link
G ELK1 ETS transcription factor ELK1 ISO PID PID:200149 PID:200162 NCBI chr  X:41,256,205...41,270,656
Ensembl chr  X:41,257,482...41,270,776 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor ISO PID PID:200149 NCBI chr27:30,893,884...31,070,401
Ensembl chr27:30,893,713...31,069,770 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase ISO PID PID:200149 NCBI chr 2:72,678,858...72,692,417
Ensembl chr 2:72,680,675...72,690,251 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200149 PID:200162 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO PID PID:200149 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541 		JBrowse link
G GAB1 GRB2 associated binding protein 1 ISO PID PID:200149 NCBI chr19:10,269...117,808
Ensembl chr19:12,616...156,694 		JBrowse link
G GRB10 growth factor receptor bound protein 10 ISO PID PID:200149 NCBI chr18:1,890,689...2,014,836
Ensembl chr18:1,890,792...2,014,839 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID PID:200149 PID:200162 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase ISO PID PID:200149 NCBI chr24:21,473,424...21,513,673
Ensembl chr24:21,473,305...21,513,564 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO PID PID:200149 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G IFNG interferon gamma ISO PID PID:200162 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 ISO PID PID:200149 NCBI chr 3:53,683,869...53,791,136
Ensembl chr 3:53,683,791...53,792,186 		JBrowse link
G ITGAV integrin subunit alpha V ISO PID PID:200149 PID:200162 NCBI chr36:28,815,215...28,890,569
Ensembl chr36:28,804,013...28,887,430 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO PID PID:200149 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451 		JBrowse link
G JAK1 Janus kinase 1 ISO PID PID:200162 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK2 Janus kinase 2 ISO in pancreatic stellate cells PID
RGD		 PMID:15948243 PID:200149 RGD:1600095 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200149 PID:200162 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200149 NCBI chr20:44,737,021...44,738,932
Ensembl chr20:44,736,832...44,763,020 		JBrowse link
G KSR1 kinase suppressor of ras 1 ISO PID PID:200149 NCBI chr 9:41,981,475...42,136,552
Ensembl chr 9:41,980,734...42,133,653 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase ISO PID PID:200149 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567 		JBrowse link
G LOC100856339 phosphatidylinositol 3-kinase regulatory subunit gamma ISO PID PID:200149 NCBI chr15:14,222,059...14,357,200
Ensembl chr15:14,235,824...14,353,832 		JBrowse link
G LRP1 LDL receptor related protein 1 ISO PID PID:200149 NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO PID PID:200149 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO PID PID:200149 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO PID PID:200149 NCBI chr20:55,465,460...55,487,629
Ensembl chr20:55,465,212...55,487,641 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO PID PID:200149 NCBI chr 5:36,142,610...36,243,673
Ensembl chr 5:36,118,388...36,241,296 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO PID PID:200149 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200149 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK10 mitogen-activated protein kinase 10 ISO PID PID:200149 NCBI chr32:9,584,437...9,889,118
Ensembl chr32:9,575,492...9,884,325 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO PID PID:200149 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO PID PID:200149 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO PID PID:200149 NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO PID PID:200149 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G MYOCD myocardin ISO PID PID:200149 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327 		JBrowse link
G NCK1 NCK adaptor protein 1 ISO PID PID:200149 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534 		JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200149 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994 		JBrowse link
G NCKAP1 NCK associated protein 1 ISO PID PID:200149 NCBI chr36:25,965,243...26,054,775
Ensembl chr36:25,965,938...26,054,760 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 ISO PID PID:200149 NCBI chr 9:5,661,792...5,679,783
Ensembl chr 9:5,662,464...5,679,570 		JBrowse link
G NHERF2 NHERF family PDZ scaffold protein 2 ISO PID PID:200149 NCBI chr 6:38,905,070...38,915,028
Ensembl chr 6:38,905,635...38,942,774 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO PID PID:200149 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 ISO PID PID:200149 NCBI chr29:28,207,445...28,340,812
Ensembl chr29:28,211,031...28,263,322 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO PID PID:200149 NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416 		JBrowse link
G PDGFA platelet derived growth factor subunit A ISO PID PID:200201 NCBI chr 6:16,271,082...16,293,246
Ensembl chr 6:16,270,104...16,292,396 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO PID PID:200149 PID:200201 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G PDGFC platelet derived growth factor C ISO PID PID:200201 NCBI chr15:54,143,637...54,239,962
Ensembl chr15:54,145,381...54,345,830 		JBrowse link
G PDGFD platelet derived growth factor D ISO PID PID:200201 NCBI chr 5:27,863,739...28,092,376
Ensembl chr 5:27,863,591...28,089,936 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO PID PID:200162 PID:200201 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO PID PID:200149 PID:200201 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200149 PID:200162 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO PID PID:200149 NCBI chr23:34,832,661...34,955,410
Ensembl chr23:34,836,540...34,993,939 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO PID PID:200149 NCBI chr 5:62,884,596...62,936,882
Ensembl chr 5:62,909,009...62,935,971 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO PID PID:200149 NCBI chr18:13,576,966...13,611,748
Ensembl chr18:13,570,999...13,611,141 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200149 PID:200162 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 ISO PID PID:200149 NCBI chr20:44,826,037...44,838,449
Ensembl chr20:44,826,339...44,836,558 		JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 ISO PID PID:200149 NCBI chr 5:33,538,354...33,604,984
Ensembl chr 5:33,532,708...33,604,984 		JBrowse link
G PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 ISO PID PID:200149 NCBI chr 5:33,472,240...33,528,369
Ensembl chr 5:33,472,771...33,528,400 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO PID PID:200149 NCBI chr20:51,156,887...51,168,131
Ensembl chr20:51,157,121...51,168,136 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO PID PID:200149 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO PID PID:200149 PID:200162 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO PID PID:200149 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052 		JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha ISO PID PID:200149 NCBI chr 1:104,974,059...105,013,745
Ensembl chr 1:104,974,072...105,013,663 		JBrowse link
G PPP2R2B protein phosphatase 2 regulatory subunit Bbeta ISO PID PID:200149 NCBI chr 2:41,005,259...41,447,048
Ensembl chr 2:41,005,644...41,459,878 		JBrowse link
G PRKCA protein kinase C alpha ISO PID PID:200149 NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630 		JBrowse link
G PRKCD protein kinase C delta ISO PID PID:200149 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKCE protein kinase C epsilon ISO PID PID:200149 NCBI chr10:47,976,929...48,464,614
Ensembl chr10:47,976,768...48,535,296 		JBrowse link
G PTEN phosphatase and tensin homolog ISO PID PID:200149 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO PID PID:200149 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200149 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO PID PID:200149 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308 		JBrowse link
G RAB4A RAB4A, member RAS oncogene family ISO PID PID:200149 NCBI chr 4:9,914,681...9,965,468
Ensembl chr 4:9,916,235...9,965,469 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family ISO PID PID:200149 NCBI chr23:23,303,650...23,333,571
Ensembl chr23:23,304,940...23,332,206 		JBrowse link
G RAC1 Rac family small GTPase 1 ISO PID PID:200149 NCBI chr 6:11,726,259...11,758,532
Ensembl chr 6:11,655,494...11,757,216 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO PID PID:200149 NCBI chr20:5,892,839...5,972,672
Ensembl chr20:5,892,834...5,972,090 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO PID PID:200149 NCBI chr17:63,725,812...63,795,359
Ensembl chr17:63,726,248...63,746,881 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family ISO PID PID:200149 NCBI chr10:10,805,359...10,816,839
Ensembl chr10:10,805,357...10,815,575 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO PID PID:200149 PID:200162 NCBI chr 9:52,429,204...52,566,775
Ensembl chr 9:52,450,597...52,563,778 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO PID PID:200149 NCBI chr 3:21,068,182...21,177,288
Ensembl chr 3:21,054,930...21,176,757 		JBrowse link
G RHOA ras homolog family member A ISO PID PID:200149 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 ISO PID PID:200149 NCBI chr  X:15,991,623...16,079,689
Ensembl chr  X:15,998,172...16,074,749 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 ISO PID PID:200149 NCBI chr 6:48,897,320...48,902,206
Ensembl chr 6:48,897,449...48,900,037 		JBrowse link
G SFN stratifin ISO PID PID:200149 NCBI chr 2:73,268,289...73,269,663
Ensembl chr 2:73,268,791...73,269,537 		JBrowse link
G SHB SH2 domain containing adaptor protein B ISO PID PID:200162 NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO PID PID:200162 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SHF Src homology 2 domain containing F ISO PID PID:200162 NCBI chr30:11,589,648...11,609,425
Ensembl chr30:11,590,211...11,609,837 		JBrowse link
G SIPA1 signal-induced proliferation-associated 1 ISO PID PID:200149 NCBI chr18:51,560,551...51,571,291
Ensembl chr18:51,560,551...51,568,885 		JBrowse link
G SLA Src like adaptor ISO PID PID:200149 NCBI chr13:29,503,304...29,590,679
Ensembl chr13:29,504,867...29,569,773 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID PID:200149 PID:200162 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SPHK1 sphingosine kinase 1 ISO PID PID:200149 NCBI chr 9:4,311,698...4,314,773
Ensembl chr 9:4,311,683...4,314,483 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200149 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G SRF serum response factor ISO PID PID:200149 PID:200162 NCBI chr12:11,664,441...11,673,846
Ensembl chr12:11,664,527...11,671,533 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO PID PID:200149 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO PID PID:200149 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A ISO PID PID:200149 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B ISO PID PID:200149 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485 		JBrowse link
G TAGLN transgelin ISO PID PID:200149 NCBI chr 5:16,390,259...16,395,471
Ensembl chr 5:16,390,573...16,397,207 		JBrowse link
G USP6NL USP6 N-terminal like ISO PID PID:200149 NCBI chr 2:24,724,454...24,894,052
Ensembl chr 2:24,743,120...24,891,668 		JBrowse link
G VAV2 vav guanine nucleotide exchange factor 2 ISO PID PID:200149 NCBI chr 9:50,103,004...50,232,753
Ensembl chr 9:50,094,447...50,230,954 		JBrowse link
G WASF2 WASP family member 2 ISO PID PID:200149 NCBI chr 2:72,800,959...72,873,728
Ensembl chr 2:72,850,525...72,872,403 		JBrowse link
G WASL WASP like actin nucleation promoting factor ISO PID PID:200149 NCBI chr14:11,828,298...11,901,190
Ensembl chr14:11,828,687...11,899,788 		JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase ISO PID PID:200149 NCBI chr 7:67,532,790...67,598,285
Ensembl chr 7:67,532,790...67,598,285 		JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta ISO PID PID:200149 NCBI chr24:32,304,808...32,325,789
Ensembl chr24:32,304,812...32,323,938 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon ISO PID PID:200149 NCBI chr 9:45,506,830...45,562,081
Ensembl chr 9:45,507,282...45,562,086 		JBrowse link
G YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma ISO PID PID:200149 NCBI chr 6:7,504,834...7,548,097
Ensembl chr 6:7,507,608...7,532,409 		JBrowse link
G YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta ISO PID PID:200149 NCBI chr26:24,785,374...24,796,603
Ensembl chr26:24,785,368...24,795,778 		JBrowse link
G YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta ISO PID PID:200149 NCBI chr17:6,660,504...6,697,954 JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO PID PID:200149 NCBI chr13:2,729,404...2,764,422 JBrowse link
scatter factor/hepatocyte growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene ISO RGD PMID:18175071 RGD:2299174 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO RGD PMID:14685170 RGD:1642762 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964 		JBrowse link
G GAB1 GRB2 associated binding protein 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr19:10,269...117,808
Ensembl chr19:12,616...156,694 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G HGF hepatocyte growth factor ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO RGD PMID:14685170 PMID:17065554 PMID:18175071 RGD:1642762 RGD:2299174 RGD:2317513 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:14685170 PMID:18175071 RGD:1642762 RGD:2299174 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
transforming growth factor-beta signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 ISO RGD PMID:29069575 RGD:151347449 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G PARK7 Parkinsonism associated deglycase ISO RGD PMID:29069575 RGD:151347449 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:15066998 RGD:1580519 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960 		JBrowse link
transforming growth factor-beta Smad dependent signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin ISO RGD PMID:12809600 RGD:2298922 NCBI chr27:36,654,328...36,695,775 JBrowse link
G ARRB2 arrestin beta 2 ISO PID PID:200227 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454 		JBrowse link
G ATF3 activating transcription factor 3 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr 7:10,784,445...10,795,285
Ensembl chr 7:10,782,064...10,794,163 		JBrowse link
G AXIN1 axin 1 ISO PID PID:200227 NCBI chr 6:40,155,797...40,218,330
Ensembl chr 6:40,158,244...40,218,343 		JBrowse link
G B9D2 B9 domain containing 2 ISO PID
RGD		 PMID:15109563 PID:200227 RGD:2298921 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor ISO PID PID:200227 NCBI chr 2:17,453,628...17,459,812
Ensembl chr 2:17,455,243...17,462,346 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO PID PID:200227 NCBI chr 4:58,800,818...58,865,830
Ensembl chr 4:58,800,813...58,865,830 		JBrowse link
G CAV1 caveolin 1 ISO PID PID:200227 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G CCN2 cellular communication network factor 2 ISO PID PID:200227 NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556 		JBrowse link
G CREBBP CREB binding protein ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176 		JBrowse link
G CTNNB1 catenin beta 1 ISO PID PID:200227 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G DACT2 dishevelled binding antagonist of beta catenin 2 ISO PID PID:200227 NCBI chr 1:55,726,041...55,736,548
Ensembl chr 1:55,726,819...55,736,505 		JBrowse link
G DAXX death domain associated protein ISO PID PID:200227 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340 		JBrowse link
G DCN decorin ISO RGD PMID:12809600 RGD:2298922 NCBI chr15:31,833,492...31,887,699
Ensembl chr15:31,833,746...31,877,417 		JBrowse link
G DYNLRB1 dynein light chain roadblock-type 1 ISO PID PID:200227 NCBI chr24:23,633,580...23,653,273
Ensembl chr24:23,633,579...23,673,921 		JBrowse link
G EIF2A eukaryotic translation initiation factor 2A ISO PID PID:200227 NCBI chr23:45,202,663...45,235,559
Ensembl chr23:45,202,022...45,235,559 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO PID
RGD		 PMID:12809600 PID:200227 RGD:2298922 NCBI chr24:19,618,581...19,643,685
Ensembl chr24:19,618,558...19,643,046 		JBrowse link
G FOXH1 forkhead box H1 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr13:37,883,554...37,887,324
Ensembl chr13:37,882,687...37,885,319 		JBrowse link
G FOXO1 forkhead box O1 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825 		JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198 		JBrowse link
G FOXO4 forkhead box O4 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr  X:55,469,738...55,477,699
Ensembl chr  X:55,469,382...55,477,699 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID PID:200227 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO PID PID:200227 NCBI chr24:23,476,619...23,630,574
Ensembl chr24:23,476,736...23,627,469 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO PID PID:200227 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase ISO PID PID:200227 NCBI chr 1:17,629,163...17,858,471
Ensembl chr 1:17,633,591...17,950,072 		JBrowse link
G OCLN occludin ISO PID PID:200227 NCBI chr 2:54,500,299...54,545,430
Ensembl chr 2:54,500,299...54,545,430 		JBrowse link
G PARD6A par-6 family cell polarity regulator alpha ISO PID PID:200227 NCBI chr 5:81,787,424...81,789,833
Ensembl chr 5:81,787,553...81,790,324 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200227 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PML PML nuclear body scaffold ISO PID PID:200227 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO PID PID:200227 NCBI chr18:50,062,352...50,065,166
Ensembl chr18:50,062,352...50,065,166 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO PID PID:200227 NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO PID PID:200227 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta ISO PID PID:200227 NCBI chr16:33,532,703...33,567,011
Ensembl chr16:33,532,958...33,566,640 		JBrowse link
G PPP2R2A protein phosphatase 2 regulatory subunit Balpha ISO PID PID:200227 NCBI chr25:31,196,613...31,282,027
Ensembl chr25:31,197,319...31,281,732 		JBrowse link
G RHOA ras homolog family member A ISO PID PID:200227 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G RNF111 ring finger protein 111 ISO PID PID:200227 NCBI chr30:23,934,156...24,027,529
Ensembl chr30:23,976,311...24,027,759 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO PID PID:200227 NCBI chr 9:34,387,084...34,590,603
Ensembl chr 9:34,387,091...34,425,292 		JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr12:13,723,535...13,842,565
Ensembl chr12:13,628,539...13,840,785
Ensembl chr12:13,628,539...13,840,785 		JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919
G SHC1 SHC adaptor protein 1 ISO PID PID:200227 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SKIL SKI like proto-oncogene ISO PID PID:200227 NCBI chr34:34,871,770...34,898,681
Ensembl chr34:34,871,574...34,894,854 		JBrowse link
G SMAD2 SMAD family member 2 ISO RGD
PID		 PMID:12809600 PMID:16959941 PMID:18684975 PID:200227 RGD:1599906 RGD:2298922 RGD:2302517 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 ISO PID
RGD		 PMID:12702545 PMID:12809600 PMID:16891311 PID:200227 RGD:1299323 RGD:1625706 RGD:2298922 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SMAD4 SMAD family member 4 ISO PID
RGD		 PMID:12809600 PMID:16959941 PID:200227 RGD:1599906 RGD:2298922 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD7 SMAD family member 7 ISO PID
RGD		 PMID:12809600 PID:200227 RGD:2298922 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 ISO PID
RGD		 PMID:12809600 PID:200227 RGD:2298922 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 ISO PID
RGD		 PMID:12809600 PID:200227 RGD:2298922 NCBI chr 9:12,348,777...12,472,636
Ensembl chr 9:12,351,627...12,471,467 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID PID:200227 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 ISO PID PID:200227 NCBI chr10:55,429,989...55,571,917
Ensembl chr10:55,429,940...55,571,916 		JBrowse link
G STRAP serine/threonine kinase receptor associated protein ISO PID PID:200227 NCBI chr27:30,800,853...30,817,578
Ensembl chr27:30,675,247...30,817,388 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO PID PID:200227 NCBI chr10:25,623,381...25,657,630
Ensembl chr10:25,623,940...25,657,543 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO PID PID:200227 NCBI chr 1:40,125,842...40,216,455
Ensembl chr 1:40,149,569...40,215,385 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO PID
RGD		 PMID:15109563 PID:200227 RGD:2298921 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242 		JBrowse link
G TGFB3 transforming growth factor beta 3 ISO PID
RGD		 PMID:12809600 PID:200227 RGD:2298922 NCBI chr 8:48,920,874...48,946,037
Ensembl chr 8:48,923,423...48,945,816 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD
PID		 PMID:12809600 PMID:18684975 PID:200227 RGD:2298922 RGD:2302517 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO RGD
PID		 PMID:12809600 PMID:14729511 PMID:18684975 PID:200227 RGD:1579921 RGD:2298922 RGD:2302517 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO PID
RGD		 PMID:12809600 PID:200227 RGD:2298922 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TGFBRAP1 transforming growth factor beta receptor associated protein 1 ISO PID PID:200227 NCBI chr10:38,096,407...38,159,641
Ensembl chr10:38,095,547...38,157,506 		JBrowse link
G WWP1 WW domain containing E3 ubiquitin protein ligase 1 ISO PID PID:200227 NCBI chr29:32,523,719...32,620,507
Ensembl chr29:32,533,619...32,625,787 		JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO PID PID:200227 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator ISO PID PID:200227 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon ISO PID PID:200227 NCBI chr 9:45,506,830...45,562,081
Ensembl chr 9:45,507,282...45,562,086 		JBrowse link
G ZFYVE16 zinc finger FYVE-type containing 16 ISO PID PID:200227 NCBI chr 3:26,662,750...26,714,184
Ensembl chr 3:26,664,068...26,699,073 		JBrowse link
G ZFYVE9 zinc finger FYVE-type containing 9 ISO PID
RGD		 PMID:12809600 PID:200227 RGD:2298922 NCBI chr15:9,014,092...9,198,178
Ensembl chr15:9,015,863...9,289,929 		JBrowse link
vascular endothelial growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 ISO PID PID:200188 NCBI chr 9:31,884,028...31,908,142
Ensembl chr 9:31,885,478...31,904,386 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200188 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G ARF1 ADP ribosylation factor 1 ISO PID PID:200188 NCBI chr14:835,476...836,424
Ensembl chr14:835,476...836,424 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO PID PID:200188 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G CALM1 calmodulin 1 ISO PID PID:200188 NCBI chr 8:61,398,231...61,408,874
Ensembl chr 8:61,398,244...61,406,195 		JBrowse link
G CALM2 calmodulin 2 ISO PID PID:200188 NCBI chr10:49,299,698...49,314,533
Ensembl chr10:49,299,897...49,314,457 		JBrowse link
G CALM3 calmodulin 3 ISO PID PID:200188 NCBI chr 1:109,284,729...109,294,491
Ensembl chr 1:109,286,155...109,294,391 		JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 ISO PID PID:200188 NCBI chr26:7,848,191...7,895,317
Ensembl chr26:7,847,466...7,893,410 		JBrowse link
G CAV1 caveolin 1 ISO PID PID:200188 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200188 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:14693680 RGD:1580560 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CDH5 cadherin 5 ISO PID PID:200188 NCBI chr 5:82,830,505...82,863,931
Ensembl chr 5:82,830,939...82,863,882 		JBrowse link
G CTNNA1 catenin alpha 1 ISO PID PID:200188 NCBI chr11:26,273,322...26,459,497
Ensembl chr11:26,143,013...26,459,091 		JBrowse link
G CTNNB1 catenin beta 1 ISO PID PID:200188 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G DNM2 dynamin 2 ISO PID PID:200188 NCBI chr20:50,398,866...50,487,303
Ensembl chr20:50,398,864...50,487,241 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO RGD PMID:14597660 RGD:1334466 NCBI chr 4:8,053,486...8,110,791
Ensembl chr 4:8,053,837...8,109,325 		JBrowse link
G EGLN2 egl-9 family hypoxia inducible factor 2 ISO RGD PMID:12876291 PMID:14597660 PMID:15563310 RGD:1334463 RGD:1334466 RGD:727754 NCBI chr 1:112,992,779...113,001,836
Ensembl chr 1:112,992,780...113,000,677 		JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 ISO RGD PMID:14597660 RGD:1334466 NCBI chr 8:12,873,755...12,901,728
Ensembl chr 8:12,875,387...12,901,709 		JBrowse link
G FBXW11 F-box and WD repeat domain containing 11 ISO PID PID:200188 NCBI chr 4:40,238,695...40,363,445
Ensembl chr 4:40,238,737...40,361,125 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase ISO PID PID:200188 NCBI chr 3:53,346,975...53,356,547
Ensembl chr 3:53,347,012...53,356,516 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO PID
RGD		 PMID:15785231 PMID:16633338 PID:200109 PID:200188 RGD:1626621 RGD:2298727 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621 		JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 ISO This is VGFR-3
Mutatons in VEGFR-3 have been implicated in lymphedema		 RGD
PID		 PMID:11683876 PMID:15563310 PMID:16633338 PID:200109 RGD:1334463 RGD:2298727 RGD:727326 NCBI chr11:1,145,643...1,184,097
Ensembl chr11:1,145,585...1,185,165 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO PID
RGD		 PMID:17658244 PID:200188 RGD:2298729 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541 		JBrowse link
G GAB1 GRB2 associated binding protein 1 ISO PID PID:200188 NCBI chr19:10,269...117,808
Ensembl chr19:12,616...156,694 		JBrowse link
G GRB10 growth factor receptor bound protein 10 ISO PID PID:200188 NCBI chr18:1,890,689...2,014,836
Ensembl chr18:1,890,792...2,014,839 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID PID:200188 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G HGS hepatocyte growth factor-regulated tyrosine kinase substrate ISO PID PID:200188 NCBI chr 9:499,071...513,375
Ensembl chr 9:499,116...514,308 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:9398602 PMID:15563310 PMID:18614764 RGD:1334463 RGD:2301848 RGD:625724 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO PID PID:200188 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO PID PID:200188 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 ISO PID PID:200188 NCBI chr 3:53,683,869...53,791,136
Ensembl chr 3:53,683,791...53,792,186 		JBrowse link
G ITGAV integrin subunit alpha V ISO PID PID:200188 NCBI chr36:28,815,215...28,890,569
Ensembl chr36:28,804,013...28,887,430 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO PID PID:200188 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451 		JBrowse link
G KDR kinase insert domain receptor ISO VEGFR-2 PID
RGD		 PMID:9442048 PMID:15563310 PMID:15785231 PMID:16633338 PMID:17658244 More... PID:200109 PID:200188 RGD:1334463 RGD:1626621 RGD:2292019 RGD:2298727 RGD:2298729 RGD:2301848 RGD:729081 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042 		JBrowse link
G LOC403934 cell division cycle 42 ISO PID PID:200188 NCBI chr 2:77,153,276...77,169,947
Ensembl chr 2:77,153,095...77,199,211 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO PID PID:200188 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO PID PID:200188 NCBI chr20:55,465,460...55,487,629
Ensembl chr20:55,465,212...55,487,641 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 ISO PID PID:200188 NCBI chr 5:42,732,751...42,762,420
Ensembl chr 5:42,700,836...42,761,736 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 ISO PID PID:200188 NCBI chr 9:15,840,714...15,962,400
Ensembl chr 9:15,840,983...15,952,026 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200188 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK11 mitogen-activated protein kinase 11 ISO PID PID:200188 NCBI chr10:16,977,133...16,984,764 JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO PID PID:200188 NCBI chr12:5,145,647...5,221,558
Ensembl chr12:5,146,037...5,220,603 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO PID PID:200188 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 ISO PID PID:200188 NCBI chr 7:5,873,088...5,903,484
Ensembl chr 7:5,814,201...5,902,220 		JBrowse link
G MYOF myoferlin ISO PID PID:200188 NCBI chr28:7,602,778...7,745,185
Ensembl chr28:7,603,129...7,745,063 		JBrowse link
G NCK1 NCK adaptor protein 1 ISO PID
RGD		 PMID:17658244 PID:200188 RGD:2298729 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534 		JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200188 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994 		JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase ISO PID PID:200188 NCBI chr30:21,123,333...21,229,907
Ensembl chr30:21,126,043...21,229,870 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO PID PID:200188 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G NRP1 neuropilin 1 ISO PID
RGD		 PMID:15563310 PMID:16633338 PID:200109 RGD:1334463 RGD:2298727 NCBI chr 2:3,416,062...3,553,929
Ensembl chr 2:3,413,821...3,552,483 		JBrowse link
G NRP2 neuropilin 2 ISO PID PID:200109 NCBI chr37:14,293,545...14,408,984
Ensembl chr37:14,293,614...14,406,949 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 ISO PID PID:200188 NCBI chr33:29,774,645...29,863,661
Ensembl chr33:29,774,593...29,987,478 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200188 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PGF placental growth factor ISO RGD PMID:7706320 PMID:16633338 RGD:2298727 RGD:633657 NCBI chr 8:48,059,554...48,110,534
Ensembl chr 8:48,059,552...48,075,170 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200188 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200188 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO PID
RGD		 PMID:17658244 PID:200188 RGD:2298729 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO PID PID:200188 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 ISO PID PID:200188 NCBI chr 5:52,809,792...52,855,072
Ensembl chr 5:52,815,609...52,876,609 		JBrowse link
G PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 ISO PID PID:200188 NCBI chr26:15,706,583...15,716,612
Ensembl chr26:15,706,678...15,715,314 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO PID PID:200188 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669 		JBrowse link
G PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 ISO PID PID:200188 NCBI chr27:5,556,433...5,570,675
Ensembl chr27:5,556,549...5,570,235 		JBrowse link
G PRKCA protein kinase C alpha ISO PID
RGD		 PMID:17658244 PID:200188 RGD:2298729 NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630 		JBrowse link
G PRKCB protein kinase C beta ISO RGD PMID:17658244 RGD:2298729 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185 		JBrowse link
G PRKCD protein kinase C delta ISO RGD
PID		 PMID:15541367 PID:200188 RGD:2298730 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:17658244 RGD:2298729 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G PTK2 protein tyrosine kinase 2 ISO RGD PMID:17658244 RGD:2298729 NCBI chr13:35,302,439...35,541,336
Ensembl chr13:35,303,380...35,541,294 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO PID PID:200188 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200188 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO PID PID:200188 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO PID PID:200188 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308 		JBrowse link
G PXN paxillin ISO PID PID:200188 NCBI chr26:16,157,231...16,224,028
Ensembl chr26:16,159,025...16,184,820 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO PID PID:200188 NCBI chr20:5,892,839...5,972,672
Ensembl chr20:5,892,834...5,972,090 		JBrowse link
G RHOA ras homolog family member A ISO PID PID:200188 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 ISO PID PID:200188 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853 		JBrowse link
G SH2D2A SH2 domain containing 2A ISO PID
RGD		 PMID:17658244 PID:200188 RGD:2298729 NCBI chr 7:41,186,721...41,195,987
Ensembl chr 7:41,186,252...41,195,122 		JBrowse link
G SHB SH2 domain containing adaptor protein B ISO PID
RGD		 PMID:17658244 PID:200188 RGD:2298729 NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200188 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G VCL vinculin ISO PID PID:200188 NCBI chr 4:24,404,279...24,518,977
Ensembl chr 4:24,404,319...24,518,633 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:12181492 PMID:15563310 PMID:15785231 PMID:16160062 PMID:16633338 More... RGD:1334463 RGD:1626621 RGD:2292019 RGD:2298727 RGD:2301848 RGD:2301956 RGD:625593 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
G VEGFB vascular endothelial growth factor B ISO RGD PMID:16633338 RGD:2298727 NCBI chr18:52,821,348...52,824,649
Ensembl chr18:52,821,365...52,824,655 		JBrowse link
G VEGFC vascular endothelial growth factor C ISO PID
RGD		 PMID:11683876 PMID:15563310 PMID:16633338 PID:200109 RGD:1334463 RGD:2298727 RGD:727326 NCBI chr16:52,883,242...52,987,684
Ensembl chr16:52,883,139...52,987,563 		JBrowse link
G VEGFD vascular endothelial growth factor D ISO This is the VEGF-D RGD
PID		 PMID:11683876 PMID:15563310 PMID:16633338 PID:200109 RGD:1334463 RGD:2298727 RGD:727326 NCBI chr  X:11,590,097...11,627,199
Ensembl chr  X:11,590,089...11,626,486 		JBrowse link
G VTN vitronectin ISO PID PID:200188 NCBI chr 9:42,617,860...42,620,825
Ensembl chr 9:42,614,941...42,630,864 		JBrowse link
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