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The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (

Term:glutathione metabolic pathway
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Accession:PW:0000134 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of glutathione - a tripeptide that acts as an antioxidant and provides protection against reactive oxygen species. It is also used in the conjugation of xenobiotics and drugs by the phase II biotransformation enzymes.
Synonyms:related_synonym: glutathione metabolic process

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glutathione metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane ISO SMPDB SMP:00015 NCBI chr 7:55,351,081...55,373,856
Ensembl chr 7:55,351,087...55,373,881
JBrowse link
G CASP7 caspase 7 ISO SMPDB SMP:00015 NCBI chr14:124,017,776...124,050,369
Ensembl chr14:124,019,164...124,050,365
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit ISO SMPDB
PMID:16137247 PMID:16183645 RGD:1582661 RGD:1582663 SMP:00015 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO RGD
PMID:16137247 PMID:16183645 RGD:1582661 RGD:1582663 SMP:00015 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G GGCT gamma-glutamylcyclotransferase ISO SMPDB SMP:00015 NCBI chr18:42,410,734...42,418,534
Ensembl chr18:42,410,792...42,418,980
JBrowse link
G GGT6 gamma-glutamyltransferase 6 ISO SMPDB SMP:00015 NCBI chr12:50,507,501...50,514,578
Ensembl chr12:50,506,907...50,510,903
JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00015 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GSR glutathione-disulfide reductase ISO SMPDB SMP:00015 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
JBrowse link
G GSS glutathione synthetase ISO SMPDB SMP:00015 NCBI chr17:38,316,199...38,342,253
Ensembl chr17:38,312,720...38,342,298
JBrowse link
G GSTO2 glutathione S-transferase omega 2 ISO SMPDB SMP:00015 NCBI chr14:115,218,179...115,242,377
Ensembl chr14:115,217,879...115,251,435
JBrowse link
G OPLAH 5-oxoprolinase, ATP-hydrolysing ISO SMPDB SMP:00015 NCBI chr 4:629,901...639,420
Ensembl chr 4:629,870...639,406
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    classic metabolic pathway 1013
      metabolic pathway of cofactors, vitamins, nutrients 239
        glutathione metabolic pathway 11
          glutathione biosynthetic pathway 0
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