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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:glutathione metabolic pathway
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Accession:PW:0000134 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of glutathione - a tripeptide that acts as an antioxidant and provides protection against reactive oxygen species. It is also used in the conjugation of xenobiotics and drugs by the phase II biotransformation enzymes.
Synonyms:related_synonym: glutathione metabolic process


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glutathione metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G CASP7 caspase 7 EXP SMPDB SMP:00015 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase IEA KEGG hsa:00480 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GGCT gamma-glutamylcyclotransferase IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr 7:30,496,621...30,504,829
Ensembl chr 7:30,496,621...30,504,841 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 IEA KEGG hsa:00480 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005 		JBrowse link
G GGT5 gamma-glutamyltransferase 5 IEA KEGG hsa:00480 NCBI chr22:24,219,654...24,245,142
Ensembl chr22:24,219,654...24,245,108 		JBrowse link
G GGT6 gamma-glutamyltransferase 6 IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr17:4,556,140...4,560,577
Ensembl chr17:4,556,927...4,560,818 		JBrowse link
G GGT7 gamma-glutamyltransferase 7 IEA KEGG hsa:00480 NCBI chr20:34,844,720...34,872,856
Ensembl chr20:34,844,720...34,872,856 		JBrowse link
G GPX1 glutathione peroxidase 1 IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX2 glutathione peroxidase 2 IEA KEGG hsa:00480 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GPX3 glutathione peroxidase 3 IEA KEGG hsa:00480 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GPX4 glutathione peroxidase 4 IEA KEGG hsa:00480 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791 		JBrowse link
G GPX5 glutathione peroxidase 5 IEA KEGG hsa:00480 NCBI chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955 		JBrowse link
G GPX6 glutathione peroxidase 6 IEA KEGG hsa:00480 NCBI chr 6:28,503,296...28,515,793
Ensembl chr 6:28,503,296...28,528,215 		JBrowse link
G GPX7 glutathione peroxidase 7 IEA KEGG hsa:00480 NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051 		JBrowse link
G GSR glutathione-disulfide reductase IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GSS glutathione synthetase IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 IEA KEGG hsa:00480 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G GSTA2 glutathione S-transferase alpha 2 IEA KEGG hsa:00480 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475 		JBrowse link
G GSTA3 glutathione S-transferase alpha 3 IEA KEGG hsa:00480 NCBI chr 6:52,896,646...52,909,698
Ensembl chr 6:52,896,639...52,909,698 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 IEA KEGG hsa:00480 NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 IEA KEGG hsa:00480 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G GSTK1 glutathione S-transferase kappa 1 IEA KEGG hsa:00480 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 IEA KEGG hsa:00480 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTM2 glutathione S-transferase mu 2 IEA KEGG hsa:00480 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551 		JBrowse link
G GSTM3 glutathione S-transferase mu 3 IEA KEGG hsa:00480 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038 		JBrowse link
G GSTM4 glutathione S-transferase mu 4 IEA KEGG hsa:00480 NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,665,496 		JBrowse link
G GSTM5 glutathione S-transferase mu 5 IEA KEGG hsa:00480 NCBI chr 1:109,711,751...109,718,268
Ensembl chr 1:109,711,780...109,775,428 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 IEA KEGG hsa:00480 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459 		JBrowse link
G GSTO2 glutathione S-transferase omega 2 IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr10:104,269,184...104,304,950
Ensembl chr10:104,268,873...104,304,950 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 IEA KEGG hsa:00480 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 IEA KEGG hsa:00480
G GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) IEA KEGG hsa:00480 NCBI chr22:23,980,134...23,983,915
Ensembl chr22:23,980,058...23,983,915 		JBrowse link
G GSTZ1 glutathione S-transferase zeta 1 IEA KEGG hsa:00480 NCBI chr14:77,321,036...77,331,597
Ensembl chr14:77,320,996...77,331,597 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 IEA KEGG hsa:00480 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 IEA KEGG hsa:00480 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G LAP3 leucine aminopeptidase 3 IEA KEGG hsa:00480 NCBI chr 4:17,577,198...17,607,970
Ensembl chr 4:17,577,198...17,607,972 		JBrowse link
G MGST1 microsomal glutathione S-transferase 1 IEA KEGG hsa:00480 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259 		JBrowse link
G MGST2 microsomal glutathione S-transferase 2 IEA KEGG hsa:00480 NCBI chr 4:139,665,819...139,754,618
Ensembl chr 4:139,665,768...139,740,745 		JBrowse link
G MGST3 microsomal glutathione S-transferase 3 IEA KEGG hsa:00480 NCBI chr 1:165,631,234...165,656,136
Ensembl chr 1:165,631,213...165,661,796 		JBrowse link
G ODC1 ornithine decarboxylase 1 IEA KEGG hsa:00480 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G OPLAH 5-oxoprolinase, ATP-hydrolysing IEA
EXP		 KEGG
SMPDB		 SMP:00015 hsa:00480 NCBI chr 8:144,050,322...144,063,961
Ensembl chr 8:144,051,266...144,063,965 		JBrowse link
G PGD phosphogluconate dehydrogenase IEA KEGG hsa:00480 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 IEA KEGG hsa:00480 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 IEA KEGG hsa:00480 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B IEA KEGG hsa:00480 NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961 		JBrowse link
G SMS spermine synthase IEA KEGG hsa:00480 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837 		JBrowse link
G SRM spermidine synthase IEA KEGG hsa:00480 NCBI chr 1:11,054,589...11,060,018
Ensembl chr 1:11,054,584...11,060,020 		JBrowse link
G TXNDC12 thioredoxin domain containing 12 IEA KEGG hsa:00480 NCBI chr 1:52,020,131...52,056,171
Ensembl chr 1:52,020,131...52,055,191 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5958
    classic metabolic pathway 1803
      metabolic pathway of cofactors, vitamins, nutrients 370
        glutathione metabolic pathway 51
          glutathione biosynthetic pathway 0
paths to the root