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The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (

Term:glutathione metabolic pathway
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Accession:PW:0000134 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of glutathione - a tripeptide that acts as an antioxidant and provides protection against reactive oxygen species. It is also used in the conjugation of xenobiotics and drugs by the phase II biotransformation enzymes.
Synonyms:related_synonym: glutathione metabolic process

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glutathione metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane ISO SMPDB SMP:00015 NCBI chr 3:52,764,418...52,779,516
Ensembl chr 3:52,764,418...52,779,746
JBrowse link
G CASP7 caspase 7 ISO SMPDB SMP:00015 NCBI chr28:24,599,866...24,630,018
Ensembl chr28:24,599,493...24,628,668
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit ISO SMPDB
PMID:16137247 PMID:16183645 RGD:1582661 RGD:1582663 SMP:00015 NCBI chr12:20,999,815...21,047,779
Ensembl chr12:21,000,792...21,047,779
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO SMPDB
PMID:16137247 PMID:16183645 RGD:1582661 RGD:1582663 SMP:00015 NCBI chr 6:55,204,602...55,244,217 JBrowse link
G GGCT gamma-glutamylcyclotransferase ISO SMPDB SMP:00015 NCBI chr14:43,244,220...43,252,930
Ensembl chr14:43,245,102...43,252,923
JBrowse link
G GGT6 gamma-glutamyltransferase 6 ISO SMPDB SMP:00015 NCBI chr 5:30,540,461...30,543,878
Ensembl chr 5:30,540,450...30,543,773
JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00015 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260
JBrowse link
G GSR glutathione-disulfide reductase ISO SMPDB SMP:00015 NCBI chr16:33,633,949...33,680,411
Ensembl chr16:33,633,968...33,679,752
JBrowse link
G GSS glutathione synthetase ISO SMPDB SMP:00015 NCBI chr24:23,973,807...24,000,281
Ensembl chr24:23,901,045...23,997,286
JBrowse link
G GSTO2 glutathione S-transferase omega 2 ISO SMPDB SMP:00015 NCBI chr28:16,580,250...16,604,977
Ensembl chr28:16,586,777...16,604,976
JBrowse link
G OPLAH 5-oxoprolinase, ATP-hydrolysing ISO SMPDB SMP:00015 NCBI chr13:37,555,035...37,564,241
Ensembl chr13:37,555,045...37,564,810
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4052
    classic metabolic pathway 1010
      metabolic pathway of cofactors, vitamins, nutrients 238
        glutathione metabolic pathway 11
          glutathione biosynthetic pathway 0
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