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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:glutathione metabolic pathway
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Accession:PW:0000134 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of glutathione - a tripeptide that acts as an antioxidant and provides protection against reactive oxygen species. It is also used in the conjugation of xenobiotics and drugs by the phase II biotransformation enzymes.
Synonyms:related_synonym: glutathione metabolic process


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glutathione metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anpep alanyl aminopeptidase, membrane IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Casp7 caspase 7 ISO SMPDB SMP:00015 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEA KEGG rno:00480 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit IEA
IMP
IDA
ISO		 KEGG
SMPDB
RGD		 PMID:16183645 PMID:16137247 SMP:00015 rno:00480, RGD:1582661, RGD:1582663 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit IEA
IMP
IDA
ISO		 KEGG
SMPDB
RGD		 PMID:16183645 PMID:16137247 SMP:00015 rno:00480, RGD:1582661, RGD:1582663 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEA KEGG rno:00480 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ggt5 gamma-glutamyltransferase 5 IEA KEGG rno:00480 NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450 		JBrowse link
G Ggt6 gamma-glutamyl transferase 6 IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr10:57,051,977...57,054,900
Ensembl chr10:57,051,825...57,067,260 		JBrowse link
G Ggt7 gamma-glutamyltransferase 7 IEA KEGG rno:00480 NCBI chr 3:143,978,073...144,004,597
Ensembl chr 3:143,978,082...144,001,492 		JBrowse link
G Gpx1 glutathione peroxidase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx2 glutathione peroxidase 2 IEA KEGG rno:00480 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx3 glutathione peroxidase 3 IEA KEGG rno:00480 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gpx4 glutathione peroxidase 4 IEA KEGG rno:00480 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gpx5 glutathione peroxidase 5 IEA KEGG rno:00480 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074 		JBrowse link
G Gpx6 glutathione peroxidase 6 IEA KEGG rno:00480 NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091 		JBrowse link
G Gpx7 glutathione peroxidase 7 IEA KEGG rno:00480 NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004 		JBrowse link
G Gpx8 glutathione peroxidase 8 IEA KEGG rno:00480 NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:44,676,454...44,680,195 		JBrowse link
G Gsr glutathione-disulfide reductase IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gss glutathione synthetase IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 IEA KEGG rno:00480 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 IEA KEGG rno:00480 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 IEA KEGG rno:00480 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 IEA KEGG rno:00480 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 IEA KEGG rno:00480 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEA KEGG rno:00480 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 IEA KEGG rno:00480 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm3 glutathione S-transferase mu 3 IEA KEGG rno:00480 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 IEA KEGG rno:00480 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 IEA KEGG rno:00480 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm6 glutathione S-transferase, mu 6 IEA KEGG rno:00480 NCBI chr 2:195,579,566...195,584,340
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 IEA KEGG rno:00480 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 IEA KEGG rno:00480 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 IEA KEGG rno:00480 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 IEA KEGG rno:00480 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gstt2 glutathione S-transferase theta 2 IEA KEGG rno:00480 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 IEA KEGG rno:00480 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 IEA KEGG rno:00480 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IEA KEGG rno:00480 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Lap3 leucine aminopeptidase 3 IEA KEGG rno:00480 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 IEA KEGG rno:00480 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 IEA KEGG rno:00480 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 IEA KEGG rno:00480 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411 		JBrowse link
G Odc1 ornithine decarboxylase 1 IEA KEGG rno:00480 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Oplah 5-oxoprolinase (ATP-hydrolysing) IEA
ISO		 KEGG
SMPDB		 SMP:00015 rno:00480 NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297 		JBrowse link
G RGD1562107 similar to class-alpha glutathione S-transferase IEA KEGG rno:00480 NCBI chr 9:23,619,691...23,628,517
Ensembl chr 9:23,620,010...23,632,333 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 IEA KEGG rno:00480 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 IEA KEGG rno:00480 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B IEA KEGG rno:00480 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G Srm spermidine synthase IEA KEGG rno:00480 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405 		JBrowse link
G Txndc12 thioredoxin domain containing 12 IEA KEGG rno:00480 NCBI chr 5:123,587,854...123,612,886
Ensembl chr 5:123,586,781...123,612,870 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6098
    classic metabolic pathway 1854
      metabolic pathway of cofactors, vitamins, nutrients 368
        glutathione metabolic pathway 52
          glutathione biosynthetic pathway 0
paths to the root