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Pathways

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:metabolic pathway of other amino acids
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Accession:PW:0000132 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of amino acids other than the common 20 amino acids found in protein. Some of these amino acids like carnitine or homocysteine derive from primary amino acids.



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beta-alanine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO SMPDB SMP:00007 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO SMPDB SMP:00007 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471
JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 ISO SMPDB SMP:00007 NCBI chr14:54,616,531...54,643,346
Ensembl chr14:73,472,255...73,495,734
JBrowse link
G CNDP1 carnosine dipeptidase 1 ISO SMPDB SMP:00007 NCBI chr18:67,920,453...67,982,843
Ensembl chr18:71,162,331...71,188,879
Ensembl chr18:71,162,331...71,188,879
JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO SMPDB SMP:00007 NCBI chr 1:99,736,145...100,576,663
Ensembl chr 1:98,457,934...99,300,100
JBrowse link
G DPYS dihydropyrimidinase ISO SMPDB SMP:00007 NCBI chr 8:101,008,090...101,096,234
Ensembl chr 8:103,160,922...103,248,303
JBrowse link
G GAD1 glutamate decarboxylase 1 ISO SMPDB SMP:00007 NCBI chr2B:58,100,623...58,145,045
Ensembl chr2B:175,558,538...175,602,944
JBrowse link
G UPB1 beta-ureidopropionase 1 ISO SMPDB SMP:00007 NCBI chr22:5,300,686...5,332,735
Ensembl chr22:22,166,370...22,197,360
JBrowse link
carnitine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH9A1 aldehyde dehydrogenase 9 family member A1 ISO SMPDB SMP:00465 NCBI chr 1:141,094,261...141,130,613
Ensembl chr 1:144,883,839...144,919,670
JBrowse link
G BBOX1 gamma-butyrobetaine hydroxylase 1 ISO SMPDB SMP:00465 NCBI chr11:26,995,120...27,083,832
Ensembl chr11:26,898,529...26,986,705
JBrowse link
G SETD7 SET domain containing 7, histone lysine methyltransferase ISO SMPDB SMP:00465 NCBI chr 4:131,869,999...131,921,342
Ensembl chr 4:143,167,190...143,227,732
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO SMPDB SMP:00465 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
G TMLHE trimethyllysine hydroxylase, epsilon ISO SMPDB SMP:00465 NCBI chr  X:144,956,906...145,081,204 JBrowse link
creatine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CKM creatine kinase, M-type ISO RGD PMID:12069495 RGD:1359082 NCBI chr19:42,255,158...42,271,467
Ensembl chr19:50,854,556...50,870,366
JBrowse link
G GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:12069495 RGD:1359082 Ensembl chr19:1,371,312...1,375,461 JBrowse link
G GATM glycine amidinotransferase ISO RGD PMID:8021264 RGD:70746 NCBI chr15:24,309,045...24,326,673
Ensembl chr15:42,639,597...42,657,209
JBrowse link
G SLC6A8 solute carrier family 6 member 8 ISO RGD PMID:12069495 RGD:1359082
glutathione metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane ISO SMPDB SMP:00015 NCBI chr15:68,479,349...68,509,238
Ensembl chr15:87,681,826...87,703,713
JBrowse link
G CASP7 caspase 7 ISO SMPDB SMP:00015 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit ISO SMPDB
RGD
PMID:16137247 PMID:16183645 RGD:1582661 RGD:1582663 SMP:00015 NCBI chr 6:53,052,145...53,102,794
Ensembl chr 6:54,687,315...54,734,994
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO RGD
SMPDB
PMID:16137247 PMID:16183645 RGD:1582661 RGD:1582663 SMP:00015 NCBI chr 1:96,548,850...96,573,273
Ensembl chr 1:95,278,665...95,297,893
JBrowse link
G GGCT gamma-glutamylcyclotransferase ISO SMPDB SMP:00015 NCBI chr 7:31,125,964...31,134,330
Ensembl chr 7:31,247,760...31,255,903
JBrowse link
G GGT6 gamma-glutamyltransferase 6 ISO SMPDB SMP:00015 NCBI chr17:4,611,707...4,615,336
Ensembl chr17:4,604,393...4,608,037
JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00015 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826
JBrowse link
G GSR glutathione-disulfide reductase ISO SMPDB SMP:00015 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557
JBrowse link
G GSS glutathione synthetase ISO SMPDB SMP:00015 NCBI chr20:31,256,734...31,284,356
Ensembl chr20:32,381,745...32,409,297
JBrowse link
G GSTO2 glutathione S-transferase omega 2 ISO SMPDB SMP:00015 NCBI chr10:100,868,109...100,901,013
Ensembl chr10:104,326,175...104,357,604
JBrowse link
G OPLAH 5-oxoprolinase, ATP-hydrolysing ISO SMPDB SMP:00015 Ensembl chr 8:143,809,440...143,818,219 JBrowse link
homocysteine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO RGD PMID:11741948 PMID:20814827 RGD:7242426 RGD:730275 NCBI chr20:30,603,701...30,626,835
Ensembl chr20:31,738,007...31,760,803
JBrowse link
G AS3MT arsenite methyltransferase ISO RGD PMID:11790780 RGD:625365 NCBI chr10:99,470,026...99,502,829
Ensembl chr10:102,933,671...102,964,692
JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO RGD PMID:15866169 RGD:1359044 NCBI chr19:10,424,993...10,476,702
Ensembl chr19:11,144,733...11,195,948
JBrowse link
G COMT catechol-O-methyltransferase ISO RGD PMID:12584150 RGD:1359089 NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:12473678 RGD:1359078 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 Ensembl chr19:1,371,312...1,375,461 JBrowse link
G GNMT glycine N-methyltransferase ISO RGD PMID:15347642 RGD:1359070 NCBI chr 6:42,550,631...42,554,385
Ensembl chr 6:43,846,560...43,849,679
JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:11566133 RGD:1359041 NCBI chr2B:21,840,342...21,892,744
Ensembl chr2B:142,036,321...142,088,315
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:20814827 RGD:7242426 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G NNMT nicotinamide N-methyltransferase ISO RGD PMID:15922112 RGD:1359084 NCBI chr11:109,174,490...109,186,758
Ensembl chr11:113,016,613...113,029,581
JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 6:147,564,783...147,623,402 JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr17:33,703,800...33,790,470
Ensembl chr17:38,651,024...38,737,202
JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:12438084 RGD:1359087 NCBI chr17:17,618,399...17,620,691
Ensembl chr17:17,835,277...17,837,180
JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO RGD PMID:15866169 RGD:1359044 NCBI chr19:46,691,795...46,705,179
Ensembl chr19:55,610,938...55,623,135
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:15866169 RGD:1359044 NCBI chr14:3,737,741...3,746,646
Ensembl chr14:21,836,984...21,846,018
JBrowse link
G PRMT6 protein arginine methyltransferase 6 ISO RGD PMID:15866169 RGD:1359044 NCBI chr 1:109,582,715...109,586,744
Ensembl chr 1:108,699,098...108,700,225
JBrowse link
G RNMT RNA guanine-7 methyltransferase ISO RGD PMID:11472630 RGD:1359071 NCBI chr18:560,744...598,216
Ensembl chr18:2,729,921...2,767,279
JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 ISO RGD PMID:11959841 RGD:1359072 NCBI chr 1:126,275,719...126,314,043
Ensembl chr 1:129,925,009...129,962,442
JBrowse link
remethylation pathway of homocysteine metabolism - cobalamin dependent term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:20814827 RGD:7242426 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:15845641 PMID:20814827 RGD:1359026 RGD:7242426 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO RGD PMID:15979034 PMID:20814827 RGD:1359037 RGD:7242426 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322
JBrowse link
remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO SMPDB SMP:00123 NCBI chr20:30,603,701...30,626,835
Ensembl chr20:31,738,007...31,760,803
JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 ISO SMPDB SMP:00123 NCBI chr 5:121,946,527...122,000,273
Ensembl chr 5:127,718,978...127,771,047
JBrowse link
G BHMT betaine--homocysteine S-methyltransferase ISO SMPDB
RGD
PMID:15845641 PMID:20346934 PMID:20814827 RGD:1359026 RGD:7242426 RGD:7242428 SMP:00123 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993
JBrowse link
G CHDH choline dehydrogenase ISO SMPDB SMP:00123 NCBI chr 3:53,751,179...53,784,437
Ensembl chr 3:54,976,780...54,982,991
JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO SMPDB SMP:00123 NCBI chr2A:85,589,301...85,595,437
Ensembl chr2A:87,141,857...87,148,322
JBrowse link
G MAT2B methionine adenosyltransferase 2 non-catalytic beta subunit ISO SMPDB SMP:00123 NCBI chr 5:158,879,425...158,895,690
Ensembl chr 5:165,656,086...165,672,176
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO SMPDB SMP:00123 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946
JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO SMPDB SMP:00123 NCBI chr17:33,703,800...33,790,470
Ensembl chr17:38,651,024...38,737,202
JBrowse link
selenoamino acid metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO SMPDB SMP:00029 NCBI chr20:30,603,701...30,626,835
Ensembl chr20:31,738,007...31,760,803
JBrowse link
G CBS cystathionine beta-synthase ISO SMPDB SMP:00029 NCBI chr21:29,361,519...29,385,610
Ensembl chr21:42,670,530...42,690,932
JBrowse link
G CTH cystathionine gamma-lyase ISO SMPDB SMP:00029 NCBI chr 1:69,646,608...69,674,301
Ensembl chr 1:71,629,333...71,677,666
JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00029 NCBI chr22:5,424,334...5,469,705 JBrowse link
G MARS1 methionyl-tRNA synthetase 1 ISO SMPDB SMP:00029 NCBI chr12:31,410,231...31,438,015
Ensembl chr12:31,668,708...31,693,839
JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO SMPDB SMP:00029 NCBI chr2A:85,589,301...85,595,437
Ensembl chr2A:87,141,857...87,148,322
JBrowse link
G MAT2B methionine adenosyltransferase 2 non-catalytic beta subunit ISO SMPDB SMP:00029 NCBI chr 5:158,879,425...158,895,690
Ensembl chr 5:165,656,086...165,672,176
JBrowse link
G METTL6 methyltransferase 6, tRNA N3-cytidine ISO SMPDB SMP:00029 NCBI chr 3:15,306,890...15,353,505
Ensembl chr 3:15,643,545...15,690,238
JBrowse link
G PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 ISO SMPDB SMP:00029 NCBI chr 4:100,119,540...100,225,575
Ensembl chr 4:110,692,601...110,798,619
JBrowse link
G SCLY selenocysteine lyase ISO SMPDB SMP:00029 NCBI chr2B:125,276,540...125,331,057
Ensembl chr2B:244,144,105...244,181,767
JBrowse link
G SEPHS2 selenophosphate synthetase 2 ISO SMPDB SMP:00029 NCBI chr16:24,523,111...24,525,390 JBrowse link
taurine and hypotaurine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADO 2-aminoethanethiol dioxygenase ISO SMPDB SMP:00021 NCBI chr10:59,312,788...59,316,554 JBrowse link
G CDO1 cysteine dioxygenase type 1 ISO SMPDB SMP:00021 NCBI chr 5:111,159,041...111,170,965
Ensembl chr 5:116,955,295...116,967,506
JBrowse link
G CSAD cysteine sulfinic acid decarboxylase ISO SMPDB SMP:00021 NCBI chr12:35,572,064...35,598,077
Ensembl chr12:36,354,437...36,379,738
JBrowse link
G GAD1 glutamate decarboxylase 1 ISO SMPDB SMP:00021 NCBI chr2B:58,100,623...58,145,045
Ensembl chr2B:175,558,538...175,602,944
JBrowse link
G GGT6 gamma-glutamyltransferase 6 ISO SMPDB SMP:00021 NCBI chr17:4,611,707...4,615,336
Ensembl chr17:4,604,393...4,608,037
JBrowse link
transsulfuration pathway of homocysteine metabolism term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase ISO SMPDB
RGD
PMID:9359866 PMID:20162368 RGD:1359024 RGD:7242427 SMP:00455 NCBI chr21:29,361,519...29,385,610
Ensembl chr21:42,670,530...42,690,932
JBrowse link
G CDO1 cysteine dioxygenase type 1 ISO RGD PMID:20162368 RGD:7242427 NCBI chr 5:111,159,041...111,170,965
Ensembl chr 5:116,955,295...116,967,506
JBrowse link
G CSAD cysteine sulfinic acid decarboxylase ISO RGD PMID:20162368 RGD:7242427 NCBI chr12:35,572,064...35,598,077
Ensembl chr12:36,354,437...36,379,738
JBrowse link
G CTH cystathionine gamma-lyase ISO RGD
SMPDB
PMID:9359866 PMID:20162368 RGD:1359024 RGD:7242427 SMP:00455 NCBI chr 1:69,646,608...69,674,301
Ensembl chr 1:71,629,333...71,677,666
JBrowse link

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