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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:Hedgehog signaling pathway
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Accession:PW:0000122 term browser browse the term
Definition:The Hedgehog signaling pathway (Hh) plays important roles in vertebrate embryogenesis, particularly in the differentiation of the neural tube, in vasculogenesis and in angiogenesis. Post-embryonically it is believed to play a homeostatic role in the maintenance of stem cells. Alteration of the pathway has been implicated in a number of human cancers.
Synonyms:related_synonym: Signaling by Hedgehog;   smoothened signaling pathway
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Hedgehog signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO PID PID:200168 PID:200172 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Arrb2 arrestin, beta 2 ISO PID PID:200168 PID:200172 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487 		JBrowse link
G Bmp2 bone morphogenetic protein 2 IEA KEGG rno:04340 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760 		JBrowse link
G Bmp4 bone morphogenetic protein 4 IEA KEGG rno:04340 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Bmp5 bone morphogenetic protein 5 IEA KEGG rno:04340 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189 		JBrowse link
G Bmp6 bone morphogenetic protein 6 IEA KEGG rno:04340 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261 		JBrowse link
G Bmp7 bone morphogenetic protein 7 IEA KEGG rno:04340 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137 		JBrowse link
G Bmp8a bone morphogenetic protein 8a IEA KEGG rno:04340 NCBI chr 5:140,874,942...140,902,881
Ensembl chr 5:140,874,503...140,902,881 		JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:20844013 RGD:5510025 NCBI chr11:69,628,703...69,704,009
Ensembl chr11:69,628,660...69,704,004 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase ISO
IEA 		KEGG
RGD		 PMID:20635334 rno:04340, RGD:5510026 NCBI chr 1:254,159,085...254,324,819
Ensembl chr 1:254,159,124...254,328,357 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated ISO PID
RGD		 PMID:20844013 PID:200168, RGD:5510025 NCBI chr 8:42,032,921...42,119,451
Ensembl chr 8:42,033,042...42,119,345 		JBrowse link
G Crebbp CREB binding protein ISO PID PID:200172 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr18:57,285,156...57,320,540
Ensembl chr18:57,287,412...57,320,538 		JBrowse link
G Csnk1d casein kinase 1, delta ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,694,279...106,754,953 		JBrowse link
G Csnk1e casein kinase 1, epsilon ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr 7:112,863,726...112,887,338
Ensembl chr 7:112,863,731...112,884,101 		JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr 8:75,334,751...75,472,339
Ensembl chr 8:75,334,895...75,467,515 		JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr 7:9,727,430...9,746,341
Ensembl chr 7:9,727,431...9,745,741 		JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr18:49,497,839...49,584,828
Ensembl chr18:49,497,839...49,584,828 		JBrowse link
G Dhh desert hedgehog signaling molecule IMP
IEA
ISO 		KEGG
PID
RGD		 PMID:11118005 PMID:20844013 PMID:20716670 PID:200168 rno:04340, RGD:634737, RGD:5510025, RGD:5510013 NCBI chr 7:131,929,857...131,935,352
Ensembl chr 7:131,929,857...131,935,352 		JBrowse link
G Disp1 dispatched RND transporter family member 1 ISO RGD PMID:20635334 RGD:5510026 NCBI chr13:97,252,574...97,398,329
Ensembl chr13:97,252,574...97,398,460 		JBrowse link
G Fbxw11 F-box and WD repeat domain containing 11 ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr10:17,737,181...17,834,834
Ensembl chr10:17,720,444...17,834,834 		JBrowse link
G Foxa2 forkhead box A2 ISO PID PID:200172 NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757 		JBrowse link
G Gas1 growth arrest-specific 1 ISO PID
RGD		 PMID:20844013 PID:200168 RGD:5510025 NCBI chr17:4,487,716...4,490,701
Ensembl chr17:4,484,283...4,497,657 		JBrowse link
G Gli1 GLI family zinc finger 1 ISO
IEA 		KEGG
PID
RGD		 PMID:20716670 PMID:20635334 PID:200172 rno:04340, RGD:5510013, RGD:5510026 NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540 		JBrowse link
G Gli2 GLI family zinc finger 2 ISO
IEA 		KEGG
PID
RGD		 PMID:20716670 PMID:20635334 PID:200168 PID:200172 rno:04340, RGD:5510013, RGD:5510026 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:32,499,678...32,716,418 		JBrowse link
G Gli3 GLI family zinc finger 3 TAS
IEA
ISO 		KEGG
PID
RGD		 PMID:15328011 PMID:20635334 PMID:20716670 PID:200172 rno:04340, RGD:1303367, RGD:5510026, RGD:5510013 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198 		JBrowse link
G Gnai1 G protein subunit alpha i1 ISO PID PID:200172 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198 		JBrowse link
G Gnai2 G protein subunit alpha i2 ISO PID PID:200172 NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:117,167,045...117,187,622 		JBrowse link
G Gnai3 G protein subunit alpha i3 ISO PID PID:200172 NCBI chr 2:198,430,920...198,468,874 JBrowse link
G Gnao1 G protein subunit alpha o1 ISO PID PID:200172 NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,040,788...11,198,437 		JBrowse link
G Gnaz G protein subunit alpha z ISO PID PID:200172 NCBI chr20:13,642,853...13,693,616
Ensembl chr20:13,644,020...13,669,287 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO PID PID:200172 NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:171,357,797...171,424,488 		JBrowse link
G Gng2 G protein subunit gamma 2 ISO PID PID:200172 NCBI chr15:4,365,222...4,466,060
Ensembl chr15:4,365,135...4,466,059 		JBrowse link
G Gpc1 glypican 1 ISO RGD PMID:20231458 RGD:5510027 NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:100,843,645...100,879,933 		JBrowse link
G Gpc2 glypican 2 IMP RGD PMID:20231458 RGD:5510027 NCBI chr12:22,391,489...22,397,822
Ensembl chr12:22,391,489...22,397,822 		JBrowse link
G Gpc3 glypican 3 ISO RGD PMID:20231458 RGD:5510027 NCBI chr  X:136,789,770...137,157,598
Ensembl chr  X:136,789,770...137,157,639 		JBrowse link
G Gpc4 glypican 4 ISO RGD PMID:20231458 RGD:5510027 NCBI chr  X:136,565,536...136,676,142
Ensembl chr  X:136,565,591...136,676,057 		JBrowse link
G Gpc5 glypican 5 ISO RGD PMID:20231458 RGD:5510027 NCBI chr15:98,614,499...100,051,285
Ensembl chr15:98,646,340...100,051,514 		JBrowse link
G Gpc6 glypican 6 ISO RGD PMID:20231458 RGD:5510027 NCBI chr15:100,437,415...101,435,038
Ensembl chr15:100,437,943...101,435,027 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO PID PID:200168 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO
IEA 		KEGG
PID
RGD		 PMID:20635334 PID:200172 rno:04340, RGD:5510026 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Hdac1 histone deacetylase 1 ISO PID PID:200172 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387 		JBrowse link
G Hdac2 histone deacetylase 2 ISO PID PID:200172 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311 		JBrowse link
G Hhat hedgehog acyltransferase ISO PID PID:200168 NCBI chr13:106,558,635...106,814,723
Ensembl chr13:106,541,866...106,811,563 		JBrowse link
G Hhip Hedgehog-interacting protein ISO
IEA 		KEGG
PID
RGD		 PMID:20844013 PID:200168 rno:04340, RGD:5510025 NCBI chr19:44,768,038...44,856,878
Ensembl chr19:44,767,536...44,862,795 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IDA RGD PMID:21720682 RGD:5510033 NCBI chr 5:154,960,818...155,061,971
Ensembl chr 5:154,960,846...155,061,971 		JBrowse link
G Ift172 intraflagellar transport 172 ISO PID PID:200172 NCBI chr 6:30,801,841...30,841,239
Ensembl chr 6:30,801,918...30,840,830 		JBrowse link
G Ift88 intraflagellar transport 88 ISO PID PID:200172 NCBI chr15:35,685,678...35,786,875
Ensembl chr15:35,688,927...35,781,634 		JBrowse link
G Ihh Indian hedgehog signaling molecule ISO
IEA 		KEGG
PID
RGD		 PMID:20716670 PMID:12082161 PMID:20844013 PID:200168 rno:04340, RGD:5510013, RGD:1299259, RGD:5510025 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203 		JBrowse link
G Kif3a kinesin family member 3a ISO PID PID:200172 NCBI chr10:38,226,388...38,263,062
Ensembl chr10:38,226,741...38,260,516 		JBrowse link
G Lgals3 galectin 3 ISO PID PID:200172 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Lrp2 LDL receptor related protein 2 ISO
IEA 		KEGG
PID
RGD		 PMID:20635334 PID:200168 rno:04340, RGD:5510026 NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 ISO PID PID:200168 NCBI chr14:79,876,002...79,888,011
Ensembl chr14:79,875,708...79,890,034 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO PID PID:200172 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 ISO PID PID:200172 NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 ISO PID PID:200172 NCBI chr 8:72,233,566...72,347,085
Ensembl chr 8:72,233,566...72,334,315 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO PID PID:200168 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200168 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEA KEGG rno:04340 NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315 		JBrowse link
G Prkcd protein kinase C, delta ISO PID PID:200172 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit IEA KEGG rno:04340 NCBI chr  X:45,701,747...45,745,210
Ensembl chr  X:45,701,747...45,745,066 		JBrowse link
G Ptch1 patched 1 ISO
IEA 		KEGG
PID
RGD		 PMID:20716670 PMID:20635334 PID:200168 PID:200172 rno:04340, RGD:5510013, RGD:5510026 NCBI chr17:1,548,449...1,613,461
Ensembl chr17:1,548,449...1,613,461 		JBrowse link
G Ptch2 patched 2 ISO PID
RGD		 PMID:20635334 PMID:20716670 PID:200168 RGD:5510013 RGD:5510026 NCBI chr 5:135,808,856...135,829,087
Ensembl chr 5:135,808,895...135,828,986 		JBrowse link
G Pthlh parathyroid hormone-like hormone ISO PID PID:200168 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454 		JBrowse link
G Rab23 RAB23, member RAS oncogene family ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr 9:43,440,047...43,463,327
Ensembl chr 9:43,440,273...43,463,325 		JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor ISO PID PID:200172 NCBI chr 5:146,940,207...146,959,501
Ensembl chr 5:146,922,611...146,959,501 		JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor ISO PID PID:200172 NCBI chr  X:35,544,873...35,563,030
Ensembl chr  X:35,544,873...35,563,030 		JBrowse link
G Sap18 Sin3A associated protein 18 ISO PID PID:200172 NCBI chr15:36,058,784...36,063,089
Ensembl chr10:87,156,914...87,158,257
Ensembl chr15:87,156,914...87,158,257 		JBrowse link
G Sap30 Sin3A associated protein 30 ISO PID PID:200172 NCBI chr16:37,758,494...37,763,825
Ensembl chr16:37,757,656...37,763,823 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO
IEA 		KEGG
PID
RGD		 PMID:20716670 PMID:12417650 PMID:20844013 PID:200168 PID:200172 rno:04340, RGD:5510013, RGD:628387, RGD:5510025 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901 		JBrowse link
G Sin3a SIN3 transcription regulator family member A ISO PID PID:200172 NCBI chr 8:66,377,471...66,432,150
Ensembl chr 8:66,381,657...66,434,542 		JBrowse link
G Sin3b SIN3 transcription regulator family member B ISO PID PID:200172 NCBI chr16:17,157,352...17,194,051
Ensembl chr16:17,157,352...17,270,664 		JBrowse link
G Smo smoothened, frizzled class receptor ISO
IEA 		KEGG
PID
RGD		 PMID:20716670 PMID:9422511 PMID:20635334 PID:200168 PID:200172 rno:04340, RGD:5510013, RGD:704355, RGD:5510026 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281 		JBrowse link
G Spop speckle type BTB/POZ protein ISO PID PID:200172 NCBI chr10:80,854,890...80,935,781
Ensembl chr10:80,854,973...80,935,146 		JBrowse link
G Sspo SCO-spondin ISO PID PID:200172 NCBI chr 4:78,725,829...78,781,330
Ensembl chr 4:78,727,275...78,781,315 		JBrowse link
G Stil STIL, centriolar assembly protein ISO PID PID:200168 NCBI chr 5:133,757,598...133,810,493
Ensembl chr 5:133,760,417...133,810,494 		JBrowse link
G Stk36 serine/threonine kinase 36 ISO
IEA 		PID
KEGG		 PID:200172 rno:04340 NCBI chr 9:83,625,905...83,652,785
Ensembl chr 9:83,626,030...83,653,525 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO
IEA 		KEGG
PID
RGD		 PMID:20716670 PID:200172 rno:04340, RGD:5510013 NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:255,199,164...255,296,981 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO PID PID:200168 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Wnt1 Wnt family member 1 IEA KEGG rno:04340 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:131,817,558...131,821,605 		JBrowse link
G Wnt10a Wnt family member 10A IEA KEGG rno:04340 NCBI chr 9:83,798,594...83,811,060
Ensembl chr 9:83,798,594...83,811,067 		JBrowse link
G Wnt10b Wnt family member 10B IEA KEGG rno:04340 NCBI chr 7:131,801,046...131,806,850
Ensembl chr 7:131,801,046...131,806,850 		JBrowse link
G Wnt11 Wnt family member 11 IEA KEGG rno:04340 NCBI chr 1:162,545,660...162,565,456
Ensembl chr 1:162,545,680...162,564,660 		JBrowse link
G Wnt16 Wnt family member 16 IEA KEGG rno:04340 NCBI chr 4:51,786,728...51,797,137
Ensembl chr 4:51,786,660...51,816,568 		JBrowse link
G Wnt2 Wnt family member 2 IEA KEGG rno:04340 NCBI chr 4:47,294,300...47,340,284
Ensembl chr 4:47,294,300...47,421,976 		JBrowse link
G Wnt2b Wnt family member 2B IEA KEGG rno:04340 NCBI chr 2:195,142,573...195,156,945
Ensembl chr 2:195,135,176...195,157,144 		JBrowse link
G Wnt3 Wnt family member 3 IEA KEGG rno:04340 NCBI chr10:89,180,224...89,224,195
Ensembl chr10:89,216,801...89,224,195 		JBrowse link
G Wnt3a Wnt family member 3A IEA KEGG rno:04340 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919 		JBrowse link
G Wnt4 Wnt family member 4 IEA KEGG rno:04340 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128 		JBrowse link
G Wnt5a Wnt family member 5A IEA KEGG rno:04340 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860 		JBrowse link
G Wnt5b Wnt family member 5B IEA KEGG rno:04340 NCBI chr 4:154,281,852...154,406,081
Ensembl chr 4:154,281,852...154,405,681 		JBrowse link
G Wnt6 Wnt family member 6 IEA KEGG rno:04340 NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:83,778,552...83,792,186 		JBrowse link
G Wnt7a Wnt family member 7A IEA KEGG rno:04340 NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:125,420,276...125,466,149 		JBrowse link
G Wnt7b Wnt family member 7B IEA KEGG rno:04340 NCBI chr 7:118,514,684...118,559,316
Ensembl chr 7:118,514,684...118,559,316 		JBrowse link
G Wnt8a Wnt family member 8A IEA KEGG rno:04340 NCBI chr18:26,411,833...26,417,426
Ensembl chr18:26,411,833...26,417,426 		JBrowse link
G Wnt8b Wnt family member 8B IEA KEGG rno:04340 NCBI chr 1:253,303,369...253,325,224
Ensembl chr 1:253,295,557...253,325,224 		JBrowse link
G Wnt9a Wnt family member 9A IEA KEGG rno:04340 NCBI chr10:44,593,691...44,620,682
Ensembl chr10:44,593,691...44,620,682 		JBrowse link
G Wnt9b Wnt family member 9B IEA KEGG rno:04340 NCBI chr10:89,135,362...89,157,065
Ensembl chr10:89,135,363...89,157,065 		JBrowse link
G Xpo1 exportin 1 ISO PID PID:200172 NCBI chr14:101,434,450...101,476,705
Ensembl chr14:101,434,517...101,476,714 		JBrowse link
G Zic2 Zic family member 2 IEA KEGG rno:04340 NCBI chr15:105,982,711...105,988,167
Ensembl chr15:105,983,342...105,988,167 		JBrowse link
altered Hedgehog signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:18772397 RGD:5490966 NCBI chr11:69,628,703...69,704,009
Ensembl chr11:69,628,660...69,704,004 		JBrowse link
G Dhh desert hedgehog signaling molecule IMP RGD PMID:11118005 RGD:634737 NCBI chr 7:131,929,857...131,935,352
Ensembl chr 7:131,929,857...131,935,352 		JBrowse link
G Gli1 GLI family zinc finger 1 ISO RGD PMID:21186299 PMID:18772397 RGD:5491005, RGD:5490966 NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540 		JBrowse link
G Gli3 GLI family zinc finger 3 ISS
ISO 		RGD PMID:15328011 PMID:18772397 RGD:1303367, RGD:5490966 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198 		JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO RGD PMID:19506583 RGD:5490965 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901 		JBrowse link
G Smo smoothened, frizzled class receptor ISO RGD PMID:9422511 RGD:704355 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      signaling pathway pertinent to development 536
        Hedgehog signaling pathway 101
          altered Hedgehog signaling pathway 7
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3866
      homeostasis pathway 1773
        cardiovascular system homeostasis pathway 423
          hematopoiesis pathway 101
            Hedgehog signaling pathway 101
              altered Hedgehog signaling pathway 7
paths to the root