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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:electron transport chain pathway
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Accession:PW:0000034 term browser browse the term
Definition:Those metabolic reactions whereby the electrons, derived from the oxidation of glucose and lipids or the degradation of amino acids, are passed to oxygen via a series of series of spatially separated complexes. The energy derived generates an electrochemical gradient that drives the synthesis of ATP. The coupling between the electron transport chain, also known as the respiratory chain, and the ATP biosynthetic pathway is known as oxidative phosphorylation. Under certain circumstances the two may be uncoupled.
Synonyms:related_synonym: ETC pathway;   Respiratory electron transport;   respiratory chain pathway;   respiratory electron transport chain


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electron transport chain pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5F1A ATP synthase F1 subunit alpha EXP SMPDB SMP:00355 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta EXP SMPDB SMP:00355 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984 		JBrowse link
G ATP5F1C ATP synthase F1 subunit gamma EXP SMPDB SMP:00355 NCBI chr10:7,788,177...7,807,801
Ensembl chr10:7,788,147...7,807,815 		JBrowse link
G ATP5F1D ATP synthase F1 subunit delta EXP SMPDB SMP:00355 NCBI chr19:1,241,751...1,244,825
Ensembl chr19:1,241,746...1,244,825 		JBrowse link
G ATP5F1E ATP synthase F1 subunit epsilon EXP SMPDB SMP:00355 NCBI chr20:59,025,475...59,032,335
Ensembl chr20:59,025,475...59,032,345 		JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 EXP SMPDB SMP:00355 NCBI chr12:53,665,170...53,681,423
Ensembl chr12:53,632,726...53,677,408 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b EXP SMPDB SMP:00355 NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773 		JBrowse link
G CYCS cytochrome c, somatic EXP SMPDB SMP:00355 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase EXP SMPDB SMP:00355 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 EXP SMPDB SMP:00355 NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 EXP SMPDB SMP:00355 NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 EXP SMPDB SMP:00355 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I EXP SMPDB SMP:00355 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445 		JBrowse link
G NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 EXP SMPDB SMP:00355 NCBI chr  X:119,871,832...119,876,662
Ensembl chr  X:119,871,832...119,876,662 		JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A TAS
EXP		 SMPDB
RGD		 PMID:16143825 SMP:00355, RGD:2306881 NCBI chr 5:218,320...268,746
Ensembl chr 5:218,303...257,082 		JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B TAS
EXP		 SMPDB
RGD		 PMID:16143825 SMP:00355, RGD:2306881 NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,032 		JBrowse link
G SDHC succinate dehydrogenase complex subunit C TAS
EXP		 SMPDB
RGD		 PMID:16143825 SMP:00355, RGD:2306881 NCBI chr 1:161,314,381...161,363,206
Ensembl chr 1:161,314,381...161,363,206 		JBrowse link
G SDHD succinate dehydrogenase complex subunit D ISO
EXP
TAS		 SMPDB
RGD		 PMID:15572694 PMID:16143825 SMP:00355, RGD:1580035, RGD:2306881 NCBI chr11:112,086,873...112,095,794
Ensembl chr11:112,086,824...112,120,016 		JBrowse link
G SLC25A4 solute carrier family 25 member 4 EXP SMPDB SMP:00355 NCBI chr 4:185,143,266...185,150,382
Ensembl chr 4:185,143,266...185,150,382 		JBrowse link
G SLC37A4 solute carrier family 37 member 4 EXP SMPDB SMP:00355 NCBI chr11:119,024,112...119,030,877
Ensembl chr11:119,023,751...119,030,906 		JBrowse link
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 EXP SMPDB SMP:00355 NCBI chr 3:48,599,002...48,609,646
Ensembl chr 3:48,599,002...48,610,976 		JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein ISO experiments done with purified bovine protein RGD PMID:3036796 RGD:2301375 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5958
    classic metabolic pathway 1803
      energy metabolic pathway 157
        oxidative phosphorylation pathway 126
          electron transport chain pathway 22
Path 2
Term Annotations click to browse term
  pathway 5958
    regulatory pathway 3604
      homeostasis pathway 1667
        energy homeostasis pathway 436
          oxidative phosphorylation pathway 126
            electron transport chain pathway 22
paths to the root