immune response pathway - Ontology Report

alpha-2-macroglobulin

ISS

RGD

PMID:11498265

RGD:1549857

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

Cd5 molecule

RGD

NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313

adaptive immune response pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd3d

CD3 delta subunit of T-cell receptor complex

ISS

RGD

PMID:12614350

RGD:1549421

NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809

Cd3g

CD3 gamma subunit of T-cell receptor complex

RGD

PMID:12410792

RGD:1549501

NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147

Fc gamma receptor 2B

RGD

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

Tnfsf13

TNF superfamily member 13

RGD

PMID:10973284

RGD:1549465

NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042

antigen processing and presentation pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B2m

beta-2 microglobulin

rno:04612

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

Calr

calreticulin

rno:04612

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

Canx

calnexin

rno:04612

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

Cd4

Cd4 molecule

rno:04612

NCBI chr 4:157,668,878...157,695,366

Cd74

CD74 molecule

rno:04612

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

Cd8a

CD8 subunit alpha

rno:04612

NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040

Cd8b

CD8 subunit beta

rno:04612

NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553

Ciita

class II, major histocompatibility complex, transactivator

rno:04612

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

Creb1

cAMP responsive element binding protein 1

rno:04612

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

Ctsb

cathepsin B

rno:04612

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

Ctsl

cathepsin L

rno:04612

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

Ctss

cathepsin S

rno:04612

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

Hsp90aa1

heat shock protein 90 alpha family class A member 1

rno:04612

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

Hsp90ab1

heat shock protein 90 alpha family class B member 1

rno:04612

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

Hspa1a

heat shock protein family A (Hsp70) member 1A

rno:04612

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

Hspa1b

heat shock protein family A (Hsp70) member 1B

rno:04612

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

Hspa1l

heat shock protein family A (Hsp70) member 1 like

rno:04612

NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571

Hspa2

heat shock protein family A (Hsp70) member 2

rno:04612

NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287

Hspa4

heat shock protein family A (Hsp70) member 4

rno:04612

NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001

Hspa5

heat shock protein family A (Hsp70) member 5

rno:04612

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

Hspa8

heat shock protein family A (Hsp70) member 8

rno:04612

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

Ifi30

IFI30, lysosomal thiol reductase

rno:04612

NCBI chr16:18,675,590...18,679,655
Ensembl chr16:18,675,613...18,681,175

Ifng

interferon gamma

rno:04612

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Kir3dl1

killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

rno:04612

NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050

Klrc1

killer cell lectin like receptor C1

rno:04612

NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425

Klrc2

killer cell lectin like receptor C2

rno:04612

NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843

Klrc3

killer cell lectin like receptor C3

rno:04612

NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336

Klrd1

killer cell lectin like receptor D1

rno:04612

NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518

Lgmn

legumain

rno:04612

NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480

Nfya

nuclear transcription factor Y subunit alpha

rno:04612

NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898

Nfyb

nuclear transcription factor Y subunit beta

rno:04612

NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565

Nfyc

nuclear transcription factor Y subunit gamma

rno:04612

NCBI chr 5:134,336,802...134,405,372
Ensembl chr 5:134,336,808...134,405,377

Pdia3

protein disulfide isomerase family A, member 3

rno:04612

NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236

Psme1

proteasome activator subunit 1

rno:04612

NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890

Psme2

proteasome activator subunit 2

rno:04612

NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946

Psme3

proteasome activator subunit 3

rno:04612

NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804

Rfx5

regulatory factor X5

rno:04612

NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717

Rfxank

regulatory factor X-associated ankyrin-containing protein

rno:04612

NCBI chr16:19,280,857...19,288,886
Ensembl chr16:19,281,475...19,460,255

Rfxap

regulatory factor X-associated protein

rno:04612

NCBI chr 2:139,008,052...139,012,235
Ensembl chr 2:139,008,055...139,012,259

RT1-A1

RT1 class Ia, locus A1

rno:04612

NCBI chr20:4,905,309...4,914,593

RT1-A2

RT1 class Ia, locus A2

rno:04612

NCBI chr20:4,870,939...4,910,183

RT1-A3

RT1 class I, locus A3

rno:04612

NCBI chr20:4,847,518...4,851,344

RT1-Ba

RT1 class II, locus Ba

rno:04612

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

RT1-Bb

RT1 class II, locus Bb

rno:04612

NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597

RT1-CE1

RT1 class I, locus1

rno:04612

NCBI chr20:3,555,779...3,559,487
Ensembl chr20:3,555,782...3,559,486

RT1-CE10

RT1 class I, locus CE10

rno:04612

NCBI chr20:3,377,284...3,380,301

RT1-CE11

RT1 class I, locus CE11

rno:04612

NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362

RT1-CE12

RT1 class I, locus CE12

rno:04612

NCBI chr20:3,338,907...3,342,547

RT1-CE13

RT1 class I, locus CE13

rno:04612

NCBI chr20:3,314,830...3,318,106

RT1-CE14

RT1 class I, locus CE14

rno:04612

NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134

RT1-CE15

RT1 class I, locus CE15

rno:04612

NCBI chr20:3,275,575...3,279,074
Ensembl chr20:3,264,172...3,279,563
Ensembl chr20:3,264,172...3,279,563

RT1-CE16

RT1 class I, locus CE16

rno:04612

NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563

RT1-CE2

RT1 class I, locus CE2

rno:04612

NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790

RT1-CE3

RT1 class I, locus CE3

rno:04612

NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081

RT1-CE4

RT1 class I, locus CE4

rno:04612

NCBI chr20:3,431,509...3,504,535

RT1-CE5

RT1 class I, locus CE5

rno:04612

NCBI chr20:3,403,418...3,479,476

RT1-CE7

RT1 class I, locus CE7

rno:04612

NCBI chr20:3,434,205...3,437,152

RT1-Cl

RT1 class Ib, locus Cl

rno:04612

RT1-Da

RT1 class II, locus Da

rno:04612

NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455

RT1-Db1

RT1 class II, locus Db1

rno:04612

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

RT1-DMa

RT1 class II, locus DMa

rno:04612

NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432

RT1-DMb

RT1 class II, locus DMb

rno:04612

NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340

RT1-DOa

RT1 class II, locus DOa

rno:04612

NCBI chr20:4,753,587...4,756,590
Ensembl chr20:4,753,598...4,756,577

RT1-DOb

RT1 class II, locus DOb

rno:04612

NCBI chr20:4,619,418...4,625,627
Ensembl chr20:4,619,816...4,625,667

RT1-Ha

RT1 class II, locus Ha

rno:04612

NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244

RT1-M1-2

RT1 class I, locus M1, gene 2

rno:04612

NCBI chr20:1,909,506...1,913,423
Ensembl chr20:1,910,656...1,917,936

RT1-M1-4

RT1 class I, locus M1, gene 4

rno:04612

NCBI chr20:1,891,365...1,893,585
Ensembl chr20:1,889,164...1,893,815

RT1-M10-1

RT1 class I, locus M10, gene 1

rno:04612

NCBI chr20:1,986,817...1,988,908
Ensembl chr20:1,986,788...2,020,117

RT1-M2

RT1 class Ib, locus M2

rno:04612

NCBI chr20:978,918...981,510
Ensembl chr20:978,935...981,723

RT1-M3-1

RT1 class Ib, locus M3, gene 1

rno:04612

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

RT1-M4

RT1 class Ib, locus M4

rno:04612

NCBI chr20:1,552,072...1,555,823

RT1-M6-1

RT1 class I, locus M6, gene 1

rno:04612

NCBI chr20:1,566,220...1,569,151
Ensembl chr20:1,583,299...1,586,215

RT1-M6-2

RT1 class I, locus M6, gene 2

rno:04612

NCBI chr20:1,583,267...1,587,099
Ensembl chr20:1,583,299...1,586,215

RT1-N1

RT1 class Ib, locus N1

rno:04612

RT1-N2

RT1 class Ib, locus N2

rno:04612

NCBI chr20:2,641,157...2,645,439
Ensembl chr20:2,641,202...2,644,900

RT1-N3

RT1 class Ib, locus N3

rno:04612

NCBI chr20:2,659,132...2,665,536
Ensembl chr20:2,661,584...2,665,530

RT1-O1

RT1 class Ib, locus O1

rno:04612

NCBI chr20:2,655,116...2,657,520
Ensembl chr20:2,655,116...2,657,520

RT1-S3

RT1 class Ib, locus S3

rno:04612

NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411

RT1-T18

RT1 class Ib, locus T18

rno:04612

NCBI chr20:2,605,261...2,608,909
Ensembl chr20:2,605,265...2,608,909

RT1-T24-1

RT1 class I, locus T24, gene 1

rno:04612

NCBI chr20:2,761,495...2,774,871
Ensembl chr20:2,718,279...2,776,154

RT1-T24-4

RT1 class I, locus T24, gene 4

rno:04612

NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511

Tap1

transporter 1, ATP binding cassette subfamily B member

rno:04612

NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901

Tap2

transporter 2, ATP binding cassette subfamily B member

rno:04612

NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407

Tapbp

TAP binding protein

rno:04612

NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181

tumor necrosis factor

rno:04612

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

B cell receptor signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKT serine/threonine kinase 1

rno:04662

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

AKT serine/threonine kinase 2

rno:04662

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

AKT serine/threonine kinase 3

rno:04662

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

Bcl10

BCL10, immune signaling adaptor

rno:04662

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

Blnk

B-cell linker

rno:04662

NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113

Btk

Bruton tyrosine kinase

rno:04662

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Card11

caspase recruitment domain family, member 11

rno:04662

NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112

Cd19

CD19 molecule

rno:04662

NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975

Cd22

CD22 molecule

rno:04662

NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322

Cd72

Cd72 molecule

rno:04662

NCBI chr 5:57,697,361...57,704,980
Ensembl chr 5:57,697,367...57,704,725

Cd79a

CD79a molecule

rno:04662

NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935

Cd79b

CD79b molecule

rno:04662

NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625

Cd81

Cd81 molecule

rno:04662

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

Chp1

calcineurin-like EF-hand protein 1

rno:04662

NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251

Chp1l1

calcineurin-like EF-hand protein 1 like 1

rno:04662

NCBI chr 5:68,570,894...68,571,875
Ensembl chr 5:68,571,232...68,571,819

Chp2

calcineurin-like EF hand protein 2

rno:04662

NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139

component of inhibitor of nuclear factor kappa B kinase complex

rno:04662

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Cr2

complement C3d receptor 2

rno:04662

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

Dapp1

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

rno:04662

NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423

Fcgr2b

Fc gamma receptor 2B

rno:04662

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

Fos proto-oncogene, AP-1 transcription factor subunit

rno:04662

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

growth factor receptor bound protein 2

rno:04662

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Gsk3b

glycogen synthase kinase 3 beta

rno:04662

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

Hras

HRas proto-oncogene, GTPase

rno:04662

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

inhibitor of nuclear factor kappa B kinase subunit beta

rno:04662

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

rno:04662

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Inpp5d

inositol polyphosphate-5-phosphatase D

rno:04662

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Jun proto-oncogene, AP-1 transcription factor subunit

rno:04662

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

Kras

KRAS proto-oncogene, GTPase

rno:04662

NCBI chr 4:178,185,418...178,218,484

Lilrb2

leukocyte immunoglobulin like receptor B2

rno:04662

NCBI chr 1:65,326,832...65,334,683
Ensembl chr 1:65,326,832...65,334,679

Lyn

LYN proto-oncogene, Src family tyrosine kinase

rno:04662

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Malt1

MALT1 paracaspase

rno:04662

NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260

mitogen activated protein kinase kinase 1

rno:04662

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

mitogen activated protein kinase kinase 2

rno:04662

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

mitogen activated protein kinase 1

rno:04662

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

mitogen activated protein kinase 3

rno:04662

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

Nfat5

nuclear factor of activated T-cells 5

rno:04662

NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675

Nfatc2

nuclear factor of activated T-cells 2

rno:04662

NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325

Nfatc3

nuclear factor of activated T-cells 3

rno:04662

NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150

Nfatc4

nuclear factor of activated T-cells 4

rno:04662

NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610

nuclear factor kappa B subunit 1

rno:04662

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

NFKB inhibitor alpha

rno:04662

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

NFKB inhibitor beta

rno:04662

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

Nfkbie

NFKB inhibitor epsilon

rno:04662

NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437

Nras

NRAS proto-oncogene, GTPase

rno:04662

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

Pik3ap1

phosphoinositide-3-kinase adaptor protein 1

rno:04662

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

rno:04662

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

rno:04662

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

rno:04662

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

phosphoinositide-3-kinase regulatory subunit 1

rno:04662

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

phosphoinositide-3-kinase regulatory subunit 2

rno:04662

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

phosphoinositide-3-kinase regulatory subunit 3

rno:04662

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

phosphoinositide-3-kinase, regulatory subunit 5

rno:04662

NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374

Plcg2

phospholipase C, gamma 2

rno:04662

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Ppp3ca

protein phosphatase 3 catalytic subunit alpha

rno:04662

NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974

Ppp3cb

protein phosphatase 3 catalytic subunit beta

rno:04662

NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981

Ppp3cc

protein phosphatase 3 catalytic subunit gamma

rno:04662

NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832

Ppp3r1

protein phosphatase 3, regulatory subunit B, alpha

rno:04662

NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907

Ppp3r2

protein phosphatase 3, regulatory subunit B, beta

rno:04662

NCBI chr 5:64,026,903...64,027,898
Ensembl chr 5:64,026,903...64,032,548

Prkcb

protein kinase C, beta

rno:04662

NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

rno:04662

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Rac family small GTPase 1

rno:04662

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

Rac2

Rac family small GTPase 2

rno:04662

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

Raf-1 proto-oncogene, serine/threonine kinase

rno:04662

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

Rasgrp3

RAS guanyl releasing protein 3

rno:04662

NCBI chr 6:19,895,361...19,993,945
Ensembl chr 6:19,895,390...19,958,578

RELA proto-oncogene, NF-kB subunit

rno:04662

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

RGD1560225

similar to nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

rno:04662

RGD1565588

similar to calcium binding protein P22

rno:04662

SOS Ras/Rac guanine nucleotide exchange factor 1

rno:04662

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

SOS Ras/Rho guanine nucleotide exchange factor 2

rno:04662

NCBI chr 6:88,042,966...88,156,140
Ensembl chr 6:88,042,966...88,156,692

Syk

spleen associated tyrosine kinase

rno:04662

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

vav guanine nucleotide exchange factor 1

rno:04662

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

vav guanine nucleotide exchange factor 2

rno:04662

NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052

vav guanine nucleotide exchange factor 3

rno:04662

NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321

classical complement pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement C3

RGD

PMID:16367929

RGD:1580273

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

complement C4A

RGD

NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080

C-reactive protein

RGD

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

complement system pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

alpha-2-macroglobulin

rno:04610

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

Bdkrb1

bradykinin receptor B1

rno:04610

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

Bdkrb2

bradykinin receptor B2

rno:04610

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

C1qa

complement C1q A chain

rno:04610

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

C1qb

complement C1q B chain

rno:04610

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

C1qc

complement C1q C chain

rno:04610

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

C1r

complement C1r

rno:04610

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

C1s

complement C1s

rno:04610

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

complement C2

rno:04610

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

complement C3

rno:04610

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

C3ar1

complement C3a receptor 1

rno:04610

NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701

C4b

complement C4B (Chido blood group)

rno:04610

NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681

C4bpa

complement component 4 binding protein, alpha

rno:04610

NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205

C4bpb

complement component 4 binding protein, beta

rno:04610

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

complement C5

rno:04610

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

C5ar1

complement C5a receptor 1

rno:04610

NCBI chr 1:76,948,622...76,959,826

complement C6

rno:04610

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

complement C7

rno:04610

NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535

C8a

complement C8 alpha chain

rno:04610

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

C8b

complement C8 beta chain

rno:04610

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

C8g

complement C8 gamma chain

rno:04610

NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495

complement C9

rno:04610

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

Cd46

CD46 molecule

rno:04610

NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445

Cd55

CD55 molecule (Cromer blood group)

IDA
IEA

KEGG
RGD

PMID:10929073

rno:04610, RGD:2326180

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

Cd59b

CD59b molecule

rno:04610

NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847

Cfb

complement factor B

rno:04610

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

Cfd

complement factor D

rno:04610

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

Cfh

complement factor H

rno:04610

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

Cfi

complement factor I

rno:04610

NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561

Cpb2

carboxypeptidase B2

rno:04610

NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556

Cr1l

complement C3b/C4b receptor 1 like

rno:04610

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

Cr2

complement C3d receptor 2

rno:04610

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

F10

coagulation factor X

rno:04610

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

F12

coagulation factor XII

rno:04610

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

F13a1

coagulation factor XIII A1 chain

rno:04610

NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700

F13b

coagulation factor XIII B chain

rno:04610

NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381

coagulation factor II, thrombin

rno:04610

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

F2r

coagulation factor II (thrombin) receptor

rno:04610

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

coagulation factor III, tissue factor

rno:04610

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

coagulation factor V

rno:04610

NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317

coagulation factor VII

rno:04610

NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610

coagulation factor VIII

rno:04610

NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857

coagulation factor IX

rno:04610

NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835

Fga

fibrinogen alpha chain

rno:04610

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

Fgb

fibrinogen beta chain

rno:04610

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

Fgg

fibrinogen gamma chain

rno:04610

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

Klkb1

kallikrein B1

rno:04610

NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053

Kng2

kininogen 2

rno:04610

NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971

Kng2l1

kininogen 2-like 1

rno:04610

NCBI chr11:77,978,795...78,002,976
Ensembl chr11:77,909,612...78,002,971

Masp1

MBL associated serine protease 1

rno:04610

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

Masp2

MBL associated serine protease 2

rno:04610

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

Mbl1

mannose binding lectin 1

rno:04610

NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174

Mbl2

mannose binding lectin 2

rno:04610

NCBI chr 1:228,016,439...228,024,736

Plat

plasminogen activator, tissue type

rno:04610

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

Plau

plasminogen activator, urokinase

rno:04610

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

Plaur

plasminogen activator, urokinase receptor

rno:04610

NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595

Plg

plasminogen

rno:04610

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

Proc

protein C, inactivator of coagulation factors Va and VIIIa

rno:04610

NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133

Pros1

protein S

rno:04610

NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286

Serpina1

serpin family A member 1

rno:04610

NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339

Serpina5

serpin family A member 5

rno:04610

NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407

Serpinc1

serpin family C member 1

rno:04610

NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293

Serpind1

serpin family D member 1

rno:04610

NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519

Serpine1

serpin family E member 1

rno:04610

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

Serpinf2

serpin family F member 2

rno:04610

NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243

Serping1

serpin family G member 1

rno:04610

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

Tfpi

tissue factor pathway inhibitor

rno:04610

NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880

Thbd

thrombomodulin

rno:04610

NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193

Vwf

von Willebrand factor

rno:04610

NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539

Fc epsilon receptor mediated signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKT serine/threonine kinase 1

SMP:00358 rno:04664

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

AKT serine/threonine kinase 2

rno:04664

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

AKT serine/threonine kinase 3

rno:04664

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

Btk

Bruton tyrosine kinase

SMP:00358 rno:04664

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Csf2

colony stimulating factor 2

SMP:00358 rno:04664

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

Fcer1a

Fc epsilon receptor Ia

SMP:00358 rno:04664

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

Fcer1g

Fc epsilon receptor Ig

SMP:00358 rno:04664

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

Fyn

FYN proto-oncogene, Src family tyrosine kinase

SMP:00358 rno:04664

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

Gab2

GRB2-associated binding protein 2

SMP:00358 rno:04664

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

growth factor receptor bound protein 2

SMP:00358 rno:04664

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Hras

HRas proto-oncogene, GTPase

SMP:00358 rno:04664

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

Ighe

immunoglobulin heavy constant epsilon

SMP:00358

interleukin 13

SMP:00358 rno:04664

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

Il3

interleukin 3

SMP:00358 rno:04664

NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066

Il4

interleukin 4

SMP:00358 rno:04664

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Il5

interleukin 5

SMP:00358 rno:04664

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

Inpp5d

inositol polyphosphate-5-phosphatase D

SMP:00358 rno:04664

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Kras

KRAS proto-oncogene, GTPase

SMP:00358 rno:04664

NCBI chr 4:178,185,418...178,218,484

Lat

linker for activation of T cells

SMP:00358 rno:04664

NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578

Lcp2

lymphocyte cytosolic protein 2

SMP:00358 rno:04664

NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559

Lyn

LYN proto-oncogene, Src family tyrosine kinase

SMP:00358 rno:04664

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

mitogen activated protein kinase kinase 1

SMP:00358 rno:04664

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

mitogen activated protein kinase kinase 2

SMP:00358 rno:04664

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

Map2k3

mitogen activated protein kinase kinase 3

SMP:00358 rno:04664

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

Map2k4

mitogen activated protein kinase kinase 4

SMP:00358 rno:04664

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

mitogen-activated protein kinase kinase 6

SMP:00358 rno:04664

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

Map2k7

mitogen activated protein kinase kinase 7

SMP:00358 rno:04664

NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222

mitogen activated protein kinase 1

SMP:00358 rno:04664

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

Mapk10

mitogen activated protein kinase 10

rno:04664

NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201

mitogen-activated protein kinase 11

rno:04664

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

mitogen-activated protein kinase 12

rno:04664

NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664

mitogen activated protein kinase 13

rno:04664

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

mitogen activated protein kinase 14

SMP:00358 rno:04664

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

mitogen activated protein kinase 3

rno:04664

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

mitogen-activated protein kinase 8

SMP:00358 rno:04664

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

mitogen-activated protein kinase 9

rno:04664

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

Ms4a2

membrane spanning 4-domains A2

SMP:00358 rno:04664

NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310

Nras

NRAS proto-oncogene, GTPase

SMP:00358 rno:04664

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

Pdk1

pyruvate dehydrogenase kinase 1

SMP:00358 rno:04664

NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

SMP:00358 rno:04664

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

rno:04664

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

rno:04664

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

phosphoinositide-3-kinase regulatory subunit 1

SMP:00358 rno:04664

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

phosphoinositide-3-kinase regulatory subunit 2

rno:04664

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

phosphoinositide-3-kinase regulatory subunit 3

rno:04664

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

phosphoinositide-3-kinase, regulatory subunit 5

rno:04664

NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374

Pla2g10

phospholipase A2, group X

rno:04664

NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000

Pla2g12a

phospholipase A2, group XIIA

rno:04664

NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740

Pla2g12b

phospholipase A2, group XIIB

rno:04664

NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743

Pla2g1b

phospholipase A2 group IB

rno:04664

NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226

Pla2g2a

phospholipase A2 group IIA

rno:04664

NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014

Pla2g2c

phospholipase A2, group IIC

rno:04664

NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377

Pla2g2d

phospholipase A2, group IID

rno:04664

NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525

Pla2g2f

phospholipase A2, group IIF

rno:04664

NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175

Pla2g3

phospholipase A2, group III

rno:04664

NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913

Pla2g4a

phospholipase A2 group IVA

SMP:00358 rno:04664

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

Pla2g4b

phospholipase A2 group IVB

rno:04664

NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853

Pla2g4e

phospholipase A2, group IVE

rno:04664

NCBI chr 3:107,132,540...107,198,609
Ensembl chr 3:107,132,541...107,198,233

Pla2g4f

phospholipase A2, group IVF

rno:04664

NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689

Pla2g5

phospholipase A2, group V

rno:04664

NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658

Pla2g6

phospholipase A2 group VI

rno:04664

NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114

Plcg1

phospholipase C, gamma 1

SMP:00358 rno:04664

NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330

Plcg2

phospholipase C, gamma 2

rno:04664

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Prkca

protein kinase C, alpha

SMP:00358 rno:04664

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

Prkcd

protein kinase C, delta

rno:04664

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

Prkce

protein kinase C, epsilon

rno:04664

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Prkcg

protein kinase C, gamma

rno:04664

NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384

Rac family small GTPase 1

SMP:00358 rno:04664

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

Rac2

Rac family small GTPase 2

rno:04664

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

Raf-1 proto-oncogene, serine/threonine kinase

SMP:00358 rno:04664

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

SOS Ras/Rac guanine nucleotide exchange factor 1

SMP:00358 rno:04664

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

SOS Ras/Rho guanine nucleotide exchange factor 2

rno:04664

NCBI chr 6:88,042,966...88,156,140
Ensembl chr 6:88,042,966...88,156,692

Syk

spleen associated tyrosine kinase

SMP:00358 rno:04664

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

tumor necrosis factor

SMP:00358 rno:04664

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

vav guanine nucleotide exchange factor 1

rno:04664

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

vav guanine nucleotide exchange factor 2

rno:04664

NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052

vav guanine nucleotide exchange factor 3

SMP:00358 rno:04664

NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321

Fc gamma receptor mediated signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKT serine/threonine kinase 1

rno:04666

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

AKT serine/threonine kinase 2

rno:04666

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

AKT serine/threonine kinase 3

rno:04666

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

Amph

amphiphysin

rno:04666

NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315

Arf6

ADP-ribosylation factor 6

rno:04666

NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114

Arpc1a

actin related protein 2/3 complex, subunit 1A

rno:04666

NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330

Arpc1b

actin related protein 2/3 complex, subunit 1B

rno:04666

NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747

Arpc2

actin related protein 2/3 complex, subunit 2

rno:04666

NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471

Arpc3

actin related protein 2/3 complex, subunit 3

rno:04666

NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651

Arpc4

actin related protein 2/3 complex, subunit 4

rno:04666

NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785

Arpc5

actin related protein 2/3 complex, subunit 5

rno:04666

NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410

Arpc5l

actin related protein 2/3 complex, subunit 5-like

rno:04666

NCBI chr 3:22,758,710...22,767,520
Ensembl chr 3:22,759,876...22,767,538
Ensembl chr 9:22,759,876...22,767,538

Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

rno:04666

NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754

Asap2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

rno:04666

NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:40,657,880...40,820,975

Cdc42

cell division cycle 42

rno:04666

NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111

Cfl1

cofilin 1

rno:04666

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

Cfl2

cofilin 2

rno:04666

NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674

Crk

CRK proto-oncogene, adaptor protein

rno:04666

NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406

Crkl

CRK like proto-oncogene, adaptor protein

rno:04666

NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238

Dnm1

dynamin 1

rno:04666

NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538

Dnm1l

dynamin 1-like

rno:04666

NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482

Dnm2

dynamin 2

rno:04666

NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157

Dnm3

dynamin 3

rno:04666

NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108

Dock2

dedicator of cytokinesis 2

rno:04666

NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808

Fcgr1a

Fc gamma receptor 1A

rno:04666

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

Fcgr2a

Fc gamma receptor 2A

rno:04666

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

Fcgr2b

Fc gamma receptor 2B

rno:04666

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

Gab2

GRB2-associated binding protein 2

rno:04666

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

Gsn

gelsolin

rno:04666

NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402

Hck

HCK proto-oncogene, Src family tyrosine kinase

rno:04666

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

Inpp5d

inositol polyphosphate-5-phosphatase D

rno:04666

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Lat

linker for activation of T cells

rno:04666

NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578

Limk1

LIM domain kinase 1

rno:04666

NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606

Limk2

LIM domain kinase 2

rno:04666

NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007

Lyn

LYN proto-oncogene, Src family tyrosine kinase

rno:04666

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

mitogen activated protein kinase kinase 1

rno:04666

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

mitogen activated protein kinase 1

rno:04666

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

mitogen activated protein kinase 3

rno:04666

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

Marcks

myristoylated alanine rich protein kinase C substrate

rno:04666

NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012

Marcksl1

MARCKS-like 1

rno:04666

NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817

Myo10

myosin X

rno:04666

NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030

Ncf1

neutrophil cytosolic factor 1

rno:04666

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

Pak1

p21 (RAC1) activated kinase 1

rno:04666

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

rno:04666

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

rno:04666

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

rno:04666

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

phosphoinositide-3-kinase regulatory subunit 1

rno:04666

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

phosphoinositide-3-kinase regulatory subunit 2

rno:04666

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

phosphoinositide-3-kinase regulatory subunit 3

rno:04666

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

phosphoinositide-3-kinase, regulatory subunit 5

rno:04666

NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374

Pip5k1a

phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha

rno:04666

NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598

Pip5k1b

phosphatidylinositol-4-phosphate 5-kinase type 1 beta

rno:04666

NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672

Pip5k1c

phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

rno:04666

NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988

Pla2g4a

phospholipase A2 group IVA

rno:04666

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

Pla2g6

phospholipase A2 group VI

rno:04666

NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114

Plcg1

phospholipase C, gamma 1

rno:04666

NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330

Plcg2

phospholipase C, gamma 2

rno:04666

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Pld1

phospholipase D1

rno:04666

NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692

Pld2

phospholipase D2

rno:04666

NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808

Plpp1

phospholipid phosphatase 1

rno:04666

NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268

Plpp2

phospholipid phosphatase 2

rno:04666

NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071

Plpp3

phospholipid phosphatase 3

rno:04666

NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205

Prkca

protein kinase C, alpha

rno:04666

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

Prkcb

protein kinase C, beta

rno:04666

NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536

Prkcd

protein kinase C, delta

rno:04666

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

Prkce

protein kinase C, epsilon

rno:04666

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Prkcg

protein kinase C, gamma

rno:04666

NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384

Ptprc

protein tyrosine phosphatase, receptor type, C

rno:04666

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Rac family small GTPase 1

rno:04666

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

Rac2

Rac family small GTPase 2

rno:04666

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

Raf-1 proto-oncogene, serine/threonine kinase

rno:04666

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

Rps6kb1

ribosomal protein S6 kinase B1

rno:04666

NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908

Rps6kb2

ribosomal protein S6 kinase B2

rno:04666

NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078

Scin

scinderin

rno:04666

NCBI chr 6:57,109,500...57,188,123
Ensembl chr 6:57,109,403...57,188,242

Sphk1

sphingosine kinase 1

rno:04666

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

Sphk2

sphingosine kinase 2

rno:04666

NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391

Syk

spleen associated tyrosine kinase

rno:04666

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

Vasp

vasodilator-stimulated phosphoprotein

rno:04666

NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061

vav guanine nucleotide exchange factor 1

rno:04666

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

vav guanine nucleotide exchange factor 2

rno:04666

NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052

vav guanine nucleotide exchange factor 3

rno:04666

NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321

Was

WASP actin nucleation promoting factor

rno:04666

NCBI chr X:14,405,105...14,413,850
Ensembl chr X:14,405,124...14,413,849

Wasf1

WASP family member 1

rno:04666

NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996

Wasf2

WASP family member 2

rno:04666

NCBI chr 5:145,336,817...145,402,041
Ensembl chr 5:145,336,842...145,399,242

Wasl

WASP like actin nucleation promoting factor

rno:04666

NCBI chr 4:53,083,536...53,132,061
Ensembl chr 4:53,083,536...53,132,022

inflammatory response pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

alpha-2-macroglobulin

ISS

RGD

PMID:11498265

RGD:1549857

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

endothelin 1

RGD

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

Ednra

endothelin receptor type A

RGD

PMID:20409845

RGD:4892591

NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049

Ednrb

endothelin receptor type B

RGD

PMID:20409845

RGD:4892591

NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115

mitogen-activated protein kinase 8

RGD

PMID:11435459

RGD:1582329

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

innate immune response pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD14 molecule

RGD

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

interleukin-1 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

absent in melanoma 2

RGD

NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975

Casp1

caspase 1

PMID:19302047 PMID:20303873

PID
RGD

PID:200089, RGD:5490210, RGD:5490211

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

component of inhibitor of nuclear factor kappa B kinase complex

PID:200089

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Erc1

ELKS/RAB6-interacting/CAST family member 1

PID:200089

NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639

inhibitor of nuclear factor kappa B kinase subunit beta

PID:200089

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

PID:200089

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Il1a

interleukin 1 alpha

PID
RGD

PID:200089, RGD:5490209

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

interleukin 1 beta

PID
RGD

PMID:20081871 PMID:20967881

PID:200089, RGD:5490209

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il1r1

interleukin 1 receptor type 1

ISO
IMP

PID
RGD

PID:200089, RGD:5490209, RGD:5130945

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

Il1r2

interleukin 1 receptor type 2

PID
RGD

PID:200089, RGD:5490209

NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725

Il1rap

interleukin 1 receptor accessory protein

RGD

RGD:5490209

NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530

Il1rn

interleukin 1 receptor antagonist

PID
RGD

PID:200089, RGD:5490209

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

Irak1

interleukin-1 receptor-associated kinase 1

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Irak2

interleukin-1 receptor-associated kinase 2

RGD

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

Irak3

interleukin-1 receptor-associated kinase 3

PID:200089

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

Irak4

interleukin-1 receptor-associated kinase 4

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837

Jun proto-oncogene, AP-1 transcription factor subunit

PID:200089

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

mitogen-activated protein kinase kinase 6

PID:200089

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

Map3k3

mitogen activated protein kinase kinase kinase 3

PID:200089

NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848

mitogen activated protein kinase kinase kinase 7

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

mitogen-activated protein kinase 8

PID:200089

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

Myd88

MYD88, innate immune signal transduction adaptor

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

nuclear factor kappa B subunit 1

PID:200089

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

Nlrp1a

NLR family, pyrin domain containing 1A

RGD

PMID:20303873

RGD:5490211

NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180

Nlrp3

NLR family, pyrin domain containing 3

PMID:19302047 PMID:20303873

RGD

RGD:5490210, RGD:5490211

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

Peli1

pellino E3 ubiquitin protein ligase 1

RGD

NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285

Peli2

pellino E3 ubiquitin protein ligase family member 2

RGD

NCBI chr15:21,393,262...21,537,737
Ensembl chr15:21,393,262...21,535,106

Peli3

pellino E3 ubiquitin protein ligase family member 3

RGD

NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200089

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200089

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Prkci

protein kinase C, iota

PID:200089

NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352

Prkcz

protein kinase C, zeta

PID:200089

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Pycard

PYD and CARD domain containing

PMID:19302047 PMID:20303873

RGD

RGD:5490210, RGD:5490211

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

RELA proto-oncogene, NF-kB subunit

PID:200089

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Sigirr

single Ig and TIR domain containing

RGD

RGD:5490209

NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269

Sqstm1

sequestosome 1

PID:200089

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

Tab1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058

Tab2

TGF-beta activated kinase 1/MAP3K7 binding protein 2

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756

Tab3

TGF-beta activated kinase 1 (MAP3K7) binding protein 3

RGD

PMID:18535784

RGD:5490218

NCBI chr X:49,972,414...50,044,658
Ensembl chr X:49,972,330...50,042,056

Ticam2

TIR domain containing adaptor molecule 2

PID:200089

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

Tollip

toll interacting protein

PMID:20086235 PMID:20967881 PMID:18535784

PID
RGD

PMID:18535784

PID:200089, RGD:5490218

NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625

Traf6

TNF receptor associated factor 6

ISO
IMP

PID
RGD

PID:200089, RGD:5490215, RGD:5130945, RGD:5490218

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Ube2n

ubiquitin-conjugating enzyme E2N

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355

Ube2v1

ubiquitin conjugating enzyme E2 V1

PID
RGD

PID:200089, RGD:5490215, RGD:5490218

NCBI chr 3:156,317,339...156,340,198
Ensembl chr 3:156,316,781...156,340,273

interleukin-6 signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

alpha-2-macroglobulin

PID:200146

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

Adam10

ADAM metallopeptidase domain 10

RGD

PMID:21145125

RGD:5686846

NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889

Adam17

ADAM metallopeptidase domain 17

PMID:22029668 PMID:21145125

RGD

RGD:5686834, RGD:5686846

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

AKT serine/threonine kinase 1

PID:200146

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Cebpb

CCAAT/enhancer binding protein beta

PID:200146

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

Cebpd

CCAAT/enhancer binding protein delta

PID:200146

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

Crp

C-reactive protein

PID:200146

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

Fgg

fibrinogen gamma chain

PID:200146

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

Fos proto-oncogene, AP-1 transcription factor subunit

PID:200146

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

Foxo1

forkhead box O1

PID:200146

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

Gab1

GRB2-associated binding protein 1

PID:200146

NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236

Gab2

GRB2-associated binding protein 2

PID:200146

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

growth factor receptor bound protein 2

PID
RGD

PMID:22029668

PID:200146, RGD:5686834

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Hck

HCK proto-oncogene, Src family tyrosine kinase

PID:200146

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

Hsp90b1

heat shock protein 90 beta family member 1

PID:200146

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

PMID:12773095 PMID:28186964 PMID:23825534 PMID:21881215 PMID:22029668

interleukin 6

ISO
IDA

PID
RGD

PID:200146, RGD:1580493, RGD:127229952, RGD:11062097, RGD:5686839, RGD:5686834

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Il6r

interleukin 6 receptor

PMID:22029668 PMID:21881215

PID
RGD

PID:200146, RGD:5686834, RGD:5686839

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

Il6st

interleukin 6 cytokine family signal transducer

ISO
IMP

PID
RGD

PMID:22029668 PMID:18280048 PMID:21881215

PID:200146, RGD:5686834, RGD:5686900, RGD:5686839

NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936

Irf1

interferon regulatory factor 1

PID:200146

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

Jak1

Janus kinase 1

PID
RGD

PMID:21881215

PID:200146, RGD:5686839

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

Jak2

Janus kinase 2

PID
RGD

PMID:21881215

PID:200146, RGD:5686839

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Jun proto-oncogene, AP-1 transcription factor subunit

PID:200146

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

Junb

JunB proto-oncogene, AP-1 transcription factor subunit

PID:200146

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

Lbp

lipopolysaccharide binding protein

PID:200146

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

Lmo4

LIM domain only 4

PID:200146

NCBI chr 2:233,264,180...233,280,881
Ensembl chr 2:233,264,182...233,280,880

Map2k4

mitogen activated protein kinase kinase 4

PID:200146

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

mitogen-activated protein kinase kinase 6

PID:200146

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

mitogen-activated protein kinase 11

PID:200146

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

mitogen activated protein kinase 14

PID:200146

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

Mcl1

MCL1 apoptosis regulator, BCL2 family member

PID:200146

NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303

Mitf

melanocyte inducing transcription factor

PID:200146

NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145

Myc

MYC proto-oncogene, bHLH transcription factor

PID:200146

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

Pias1

protein inhibitor of activated STAT, 1

PID:200146

NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905

Pias3

protein inhibitor of activated STAT, 3

PID:200146

NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PID:200146

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphoinositide-3-kinase regulatory subunit 1

PID:200146

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

Prkcd

protein kinase C, delta

PID:200146

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

Ptpn11

protein tyrosine phosphatase, non-receptor type 11

PID
RGD

PMID:22029668

PID:200146, RGD:5686834

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

Rac family small GTPase 1

PID:200146

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

Socs3

suppressor of cytokine signaling 3

PID:200146

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

SOS Ras/Rac guanine nucleotide exchange factor 1

PMID:22029668 PMID:9815779

PID
RGD

PID:200146, RGD:5686834, RGD:155631264

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

SOS Ras/Rho guanine nucleotide exchange factor 2

RGD

PMID:22029668

RGD:5686834

NCBI chr 6:88,042,966...88,156,140
Ensembl chr 6:88,042,966...88,156,692

Stat1

signal transducer and activator of transcription 1

PMID:22029668 PMID:21881215

PID
RGD

PID:200146, RGD:5686834, RGD:5686839

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

Stat3

signal transducer and activator of transcription 3

PMID:22029668 PMID:21881215

PID
RGD

PID:200146, RGD:5686834, RGD:5686839

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

Timp1

TIMP metallopeptidase inhibitor 1

PID:200146

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

Tnfsf11

TNF superfamily member 11

PID:200146

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

Tyk2

tyrosine kinase 2

PID
RGD

PMID:21881215

PID:200146, RGD:5686839

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

vav guanine nucleotide exchange factor 1

PID:200146

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

lectin complement pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mbl2

mannose binding lectin 2

RGD

PMID:9920905

RGD:4889148

NCBI chr 1:228,016,439...228,024,736

NOD-like receptor signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Birc2

baculoviral IAP repeat-containing 2

rno:04621

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

Birc3

baculoviral IAP repeat-containing 3

rno:04621

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

Card6

caspase recruitment domain family, member 6

rno:04621

NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846

Card9

caspase recruitment domain family, member 9

rno:04621

NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237

Casp1

caspase 1

rno:04621

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

Casp8

caspase 8

rno:04621

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

Ccl12

C-C motif chemokine ligand 12

rno:04621

NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780

Ccl5

C-C motif chemokine ligand 5

rno:04621

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

component of inhibitor of nuclear factor kappa B kinase complex

rno:04621

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Cxcl1

C-X-C motif chemokine ligand 1

rno:04621

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

Cxcl2

C-X-C motif chemokine ligand 2

rno:04621

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

Hsp90aa1

heat shock protein 90 alpha family class A member 1

rno:04621

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

Hsp90ab1

heat shock protein 90 alpha family class B member 1

rno:04621

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

Hsp90b1

heat shock protein 90 beta family member 1

rno:04621

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

inhibitor of nuclear factor kappa B kinase subunit beta

rno:04621

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

rno:04621

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Il18

interleukin 18

rno:04621

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

interleukin 1 beta

rno:04621

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

interleukin 6

rno:04621

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

mitogen activated protein kinase kinase kinase 7

rno:04621

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

mitogen activated protein kinase 1

rno:04621

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

Mapk10

mitogen activated protein kinase 10

rno:04621

NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201

mitogen-activated protein kinase 11

rno:04621

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

mitogen-activated protein kinase 12

rno:04621

NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664

mitogen activated protein kinase 13

rno:04621

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

mitogen activated protein kinase 14

rno:04621

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

mitogen activated protein kinase 3

rno:04621

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

mitogen-activated protein kinase 8

rno:04621

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

mitogen-activated protein kinase 9

rno:04621

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

Mefv

MEFV innate immunity regulator, pyrin

rno:04621

NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973

Naip5

NLR family, apoptosis inhibitory protein 5

rno:04621

NCBI chr 2:31,557,706...31,608,722
Ensembl chr 2:31,557,817...31,608,634

nuclear factor kappa B subunit 1

rno:04621

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

NFKB inhibitor alpha

rno:04621

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

NFKB inhibitor beta

rno:04621

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

Nlrp1a

NLR family, pyrin domain containing 1A

rno:04621

NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180

Nlrp1b

NLR family, pyrin domain containing 1B

rno:04621

NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774

Nlrp3

NLR family, pyrin domain containing 3

rno:04621

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

Nod1

nucleotide-binding oligomerization domain containing 1

rno:04621

NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404

Nod2

nucleotide-binding oligomerization domain containing 2

IDA
IEA

KEGG
RGD

PMID:16973131

rno:04621, RGD:1643119

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Pstpip1

proline-serine-threonine phosphatase-interacting protein 1

rno:04621

NCBI chr 8:56,499,287...56,538,593
Ensembl chr 8:56,499,590...56,538,580

Pycard

PYD and CARD domain containing

rno:04621

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

RELA proto-oncogene, NF-kB subunit

rno:04621

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Ripk2

receptor-interacting serine-threonine kinase 2

rno:04621

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

Sugt1

SGT1 homolog, MIS12 kinetochore complex assembly cochaperone

rno:04621

NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150

tumor necrosis factor

rno:04621

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Traf6

TNF receptor associated factor 6

rno:04621

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Xiap

X-linked inhibitor of apoptosis

rno:04621

NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700

pro-inflammatory cytokine mediated pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hmgb1

high mobility group box 1

MMO:0000166, MMO:0000669, MMO:0000656

RGD

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

Icam1

intercellular adhesion molecule 1

MMO:0000166, MMO:0000669, MMO:0000656

RGD

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

interleukin 1 beta

MMO:0000166, MMO:0000669, MMO:0000656

RGD

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

interleukin 6

MMO:0000166, MMO:0000669, MMO:0000656

RGD

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

nuclear factor kappa B subunit 1

MMO:0000166, MMO:0000669, MMO:0000656

RGD

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

Ptgs2

prostaglandin-endoperoxide synthase 2

MMO:0000166, MMO:0000669, MMO:0000656

RGD

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

tumor necrosis factor

RGD

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

receptor for advanced glycation end-products signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ager

advanced glycosylation end product-specific receptor

RGD

PMID:22293957

RGD:7245565

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atg12

autophagy related 12

rno:04622

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

Atg5

autophagy related 5

rno:04622

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

Azi2

5-azacytidine induced 2

rno:04622

NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847

Casp8

caspase 8

rno:04622

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

component of inhibitor of nuclear factor kappa B kinase complex

rno:04622

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Cxcl10

C-X-C motif chemokine ligand 10

rno:04622

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

Cyld

CYLD lysine 63 deubiquitinase

rno:04622

NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658

Ddx3

DEAD-box helicase 3

rno:04622

NCBI chr13:98,520,538...98,523,707
Ensembl chr13:98,520,201...98,524,176

Ddx3x

DEAD-box helicase 3, X-linked

rno:04622

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

Ddx3y

DEAD box helicase 3, Y-linked

rno:04622

NCBI chr Y:1,115,095...1,135,754
Ensembl chr Y:1,116,309...1,135,706

Dhx58

DEXH-box helicase 58

rno:04622

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Fadd

Fas associated via death domain

rno:04622

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

Ifih1

interferon induced with helicase C domain 1

rno:04622

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

Ifna1

interferon, alpha 1

rno:04622

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

Ifna11

interferon alpha family, gene 11

rno:04622

interferon alpha 2

rno:04622

NCBI chr 5:103,258,617...103,259,195

Ifna4

interferon, alpha 4

rno:04622

NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052

Ifna4l1

interferon, alpha 4 like 1

rno:04622

NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302

Ifna5

interferon, alpha 5

rno:04622

NCBI chr 5:103,187,852...103,188,430

Ifnb1

interferon beta 1

rno:04622

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

Ifnk

interferon kappa

rno:04622

NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281

inhibitor of nuclear factor kappa B kinase subunit beta

rno:04622

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

Ikbke

inhibitor of nuclear factor kappa B kinase subunit epsilon

rno:04622

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

rno:04622

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Il12a

interleukin 12A

rno:04622

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

Il12b

interleukin 12B

rno:04622

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

Irf3

interferon regulatory factor 3

rno:04622

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

Irf7

interferon regulatory factor 7

rno:04622

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

Isg15

ISG15 ubiquitin-like modifier

rno:04622

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

Map3k1

mitogen-activated protein kinase kinase kinase 1

rno:04622

NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463

mitogen activated protein kinase kinase kinase 7

rno:04622

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

Mapk10

mitogen activated protein kinase 10

rno:04622

NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201

mitogen-activated protein kinase 11

rno:04622

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

mitogen-activated protein kinase 12

rno:04622

NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664

mitogen activated protein kinase 13

rno:04622

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

mitogen activated protein kinase 14

rno:04622

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

mitogen-activated protein kinase 8

rno:04622

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

mitogen-activated protein kinase 9

rno:04622

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

Mavs

mitochondrial antiviral signaling protein

rno:04622

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

nuclear factor kappa B subunit 1

rno:04622

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

NFKB inhibitor alpha

rno:04622

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

NFKB inhibitor beta

rno:04622

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

Nlrx1

NLR family member X1

rno:04622

NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484

Otud5

OTU deubiquitinase 5

rno:04622

NCBI chr X:14,626,173...14,659,331
Ensembl chr X:14,626,164...14,659,573

Pin1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

rno:04622

NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785

RELA proto-oncogene, NF-kB subunit

rno:04622

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

Rig1

RNA sensor RIG-1

rno:04622

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

Ripk1

receptor interacting serine/threonine kinase 1

rno:04622

NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824

Rnf125

ring finger protein 125

rno:04622

NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983

Tank

TRAF family member-associated NFKB activator

rno:04622

NCBI chr 3:46,114,230...46,190,270
Ensembl chr 3:46,114,274...46,190,264

Tbk1

TANK-binding kinase 1

rno:04622

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

Tbkbp1

TBK1 binding protein 1

rno:04622

NCBI chr10:82,120,558...82,135,749
Ensembl chr10:82,120,564...82,134,352

Tkfc

triokinase and FMN cyclase

rno:04622

NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737

tumor necrosis factor

rno:04622

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tradd

TNFRSF1A-associated via death domain

rno:04622

NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638

Traf2

Tnf receptor-associated factor 2

rno:04622

NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538

Traf3

Tnf receptor-associated factor 3

rno:04622

NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481

Traf6

TNF receptor associated factor 6

rno:04622

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Trim25

tripartite motif-containing 25

rno:04622

NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257

T cell receptor signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKT serine/threonine kinase 1

rno:04660

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

AKT serine/threonine kinase 2

rno:04660

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

AKT serine/threonine kinase 3

rno:04660

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

Bcl10

BCL10, immune signaling adaptor

rno:04660

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

Card11

caspase recruitment domain family, member 11

rno:04660

NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112

Cbl

Cbl proto-oncogene

rno:04660

NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176

Cblb

Cbl proto-oncogene B

rno:04660

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

Cblc

Cbl proto-oncogene C

rno:04660

NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755

Cd247

Cd247 molecule

rno:04660

NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263

Cd28

Cd28 molecule

rno:04660

NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685

Cd3d

CD3 delta subunit of T-cell receptor complex

rno:04660

NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809

Cd3e

CD3 epsilon subunit of T-cell receptor complex

rno:04660

NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022

Cd3g

CD3 gamma subunit of T-cell receptor complex

rno:04660

NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147

Cd4

Cd4 molecule

rno:04660

NCBI chr 4:157,668,878...157,695,366

Cd40lg

CD40 ligand

rno:04660

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

Cd8a

CD8 subunit alpha

rno:04660

NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040

Cd8b

CD8 subunit beta

rno:04660

NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553

Cdc42

cell division cycle 42

rno:04660

NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111

Cdk4

cyclin-dependent kinase 4

rno:04660

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

Chp1

calcineurin-like EF-hand protein 1

rno:04660

NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251

Chp1l1

calcineurin-like EF-hand protein 1 like 1

rno:04660

NCBI chr 5:68,570,894...68,571,875
Ensembl chr 5:68,571,232...68,571,819

Chp2

calcineurin-like EF hand protein 2

rno:04660

NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139

component of inhibitor of nuclear factor kappa B kinase complex

rno:04660

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Csf2

colony stimulating factor 2

rno:04660

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

Ctla4

cytotoxic T-lymphocyte-associated protein 4

rno:04660

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

Dlg1

discs large MAGUK scaffold protein 1

rno:04660

NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689

Fos proto-oncogene, AP-1 transcription factor subunit

rno:04660

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

Fyn

FYN proto-oncogene, Src family tyrosine kinase

rno:04660

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

Grap2

GRB2-related adaptor protein 2

rno:04660

NCBI chr 7:112,117,142...112,190,880
Ensembl chr 7:112,117,142...112,190,877

growth factor receptor bound protein 2

rno:04660

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

Gsk3b

glycogen synthase kinase 3 beta

rno:04660

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

Hras

HRas proto-oncogene, GTPase

rno:04660

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

Icos

inducible T-cell co-stimulator

rno:04660

NCBI chr 9:62,368,075...62,406,900
Ensembl chr 9:62,383,832...62,405,672

Ifng

interferon gamma

rno:04660

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

inhibitor of nuclear factor kappa B kinase subunit beta

rno:04660

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

rno:04660

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Il10

interleukin 10

rno:04660

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

Il2

interleukin 2

rno:04660

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Il4

interleukin 4

rno:04660

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Il5

interleukin 5

rno:04660

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

Itk

IL2-inducible T-cell kinase

rno:04660

NCBI chr10:30,753,344...30,814,685
Ensembl chr10:30,753,344...30,814,685

Jun proto-oncogene, AP-1 transcription factor subunit

rno:04660

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

Kras

KRAS proto-oncogene, GTPase

rno:04660

NCBI chr 4:178,185,418...178,218,484

Lat

linker for activation of T cells

rno:04660

NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578

Lck

LCK proto-oncogene, Src family tyrosine kinase

rno:04660

NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794

Lcp2

lymphocyte cytosolic protein 2

rno:04660

NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559

Malt1

MALT1 paracaspase

rno:04660

NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260

mitogen activated protein kinase kinase 1

rno:04660

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

mitogen activated protein kinase kinase 2

rno:04660

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

Map2k7

mitogen activated protein kinase kinase 7

rno:04660

NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222

Map3k14

mitogen-activated protein kinase kinase kinase 14

rno:04660

NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523

mitogen activated protein kinase kinase kinase 7

rno:04660

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

Map3k8

mitogen-activated protein kinase kinase kinase 8

rno:04660

NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216

mitogen activated protein kinase 1

rno:04660

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

mitogen-activated protein kinase 11

rno:04660

NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395

mitogen-activated protein kinase 12

rno:04660

NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664

mitogen activated protein kinase 13

rno:04660

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

mitogen activated protein kinase 14

rno:04660

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

mitogen activated protein kinase 3

rno:04660

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

mitogen-activated protein kinase 9

rno:04660

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

Nck1

NCK adaptor protein 1

rno:04660

NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300

Nck2

NCK adaptor protein 2

rno:04660

NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307

Nfat5

nuclear factor of activated T-cells 5

rno:04660

NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675

Nfatc2

nuclear factor of activated T-cells 2

rno:04660

NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325

Nfatc3

nuclear factor of activated T-cells 3

rno:04660

NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150

Nfatc4

nuclear factor of activated T-cells 4

rno:04660

NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610

nuclear factor kappa B subunit 1

rno:04660

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

NFKB inhibitor alpha

rno:04660

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

NFKB inhibitor beta

rno:04660

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

Nfkbie

NFKB inhibitor epsilon

rno:04660

NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437

Nras

NRAS proto-oncogene, GTPase

rno:04660

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

Pak1

p21 (RAC1) activated kinase 1

rno:04660

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

Pak2

p21 (RAC1) activated kinase 2

rno:04660

NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816

Pak3

p21 (RAC1) activated kinase 3

rno:04660

NCBI chr X:107,116,308...107,374,342
Ensembl chr X:107,260,898...107,368,314

Pak4

p21 (RAC1) activated kinase 4

rno:04660

NCBI chr 1:83,849,904...83,889,188
Ensembl chr 1:83,849,904...83,859,413

Pak5

p21 (RAC1) activated kinase 5

rno:04660

NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930

Pak6

p21 (RAC1) activated kinase 6

rno:04660

NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975

Pdcd1

programmed cell death 1

rno:04660

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

Pdk1

pyruvate dehydrogenase kinase 1

rno:04660

NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

rno:04660

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

rno:04660

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

rno:04660

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

phosphoinositide-3-kinase regulatory subunit 1

rno:04660

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

phosphoinositide-3-kinase regulatory subunit 2

rno:04660

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

phosphoinositide-3-kinase regulatory subunit 3

rno:04660

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

phosphoinositide-3-kinase, regulatory subunit 5

rno:04660

NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374

Plcg1

phospholipase C, gamma 1

rno:04660

NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330

Ppp3ca

protein phosphatase 3 catalytic subunit alpha

rno:04660

NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974

Ppp3cb

protein phosphatase 3 catalytic subunit beta

rno:04660

NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981

Ppp3cc

protein phosphatase 3 catalytic subunit gamma

rno:04660

NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832

Ppp3r1

protein phosphatase 3, regulatory subunit B, alpha

rno:04660

NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907

Ppp3r2

protein phosphatase 3, regulatory subunit B, beta

rno:04660

NCBI chr 5:64,026,903...64,027,898
Ensembl chr 5:64,026,903...64,032,548

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

rno:04660

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Ptprc

protein tyrosine phosphatase, receptor type, C

rno:04660

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Raf-1 proto-oncogene, serine/threonine kinase

rno:04660

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

Rasgrp1

RAS guanyl releasing protein 1

rno:04660

NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056

RELA proto-oncogene, NF-kB subunit

rno:04660

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

RGD1560225

similar to nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

rno:04660

RGD1565588

similar to calcium binding protein P22

rno:04660

Rhoa

ras homolog family member A

rno:04660

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

RSA-14-44

RSA-14-44 protein

rno:04660

NCBI chr 4:95,251,657...95,253,029
Ensembl chr 4:95,251,610...95,253,088

SOS Ras/Rac guanine nucleotide exchange factor 1

rno:04660

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

SOS Ras/Rho guanine nucleotide exchange factor 2

rno:04660

NCBI chr 6:88,042,966...88,156,140
Ensembl chr 6:88,042,966...88,156,692

Tec

tec protein tyrosine kinase

rno:04660

NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557

tumor necrosis factor

rno:04660

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

vav guanine nucleotide exchange factor 1

rno:04660

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

vav guanine nucleotide exchange factor 2

rno:04660

NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052

vav guanine nucleotide exchange factor 3

rno:04660

NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321

Zap70

zeta chain of T cell receptor associated protein kinase 70

rno:04660

NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700

Toll-like receptor signaling pathway

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKT serine/threonine kinase 1

rno:04620

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

AKT serine/threonine kinase 2

rno:04620

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

AKT serine/threonine kinase 3

rno:04620

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

Casp8

caspase 8

rno:04620

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

Ccl3

C-C motif chemokine ligand 3

rno:04620

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

Ccl5

C-C motif chemokine ligand 5

rno:04620

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

Cd14

CD14 molecule

KEGG
RGD

PMID:22119168

rno:04620, RGD:7247704

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

Cd40

CD40 molecule

rno:04620

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

Cd80

Cd80 molecule

rno:04620

NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030

Cd86

CD86 molecule

rno:04620

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

component of inhibitor of nuclear factor kappa B kinase complex

rno:04620

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

Ctsk

cathepsin K

rno:04620

NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550

Cxcl10

C-X-C motif chemokine ligand 10

rno:04620

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

Cxcl11

C-X-C motif chemokine ligand 11

rno:04620

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

Cxcl9

C-X-C motif chemokine ligand 9

rno:04620

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

Fadd

Fas associated via death domain

rno:04620

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

Fos proto-oncogene, AP-1 transcription factor subunit

rno:04620

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

Ifna1

interferon, alpha 1

rno:04620

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

Ifna11

interferon alpha family, gene 11

rno:04620

interferon alpha 2

rno:04620

NCBI chr 5:103,258,617...103,259,195

Ifna4

interferon, alpha 4

rno:04620

NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052

Ifna4l1

interferon, alpha 4 like 1

rno:04620

NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302

Ifna5

interferon, alpha 5

rno:04620

NCBI chr 5:103,187,852...103,188,430

Ifnar1

interferon alpha and beta receptor subunit 1

rno:04620

NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979

Ifnb1

interferon beta 1

rno:04620

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

inhibitor of nuclear factor kappa B kinase subunit beta

rno:04620

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

Ikbke

inhibitor of nuclear factor kappa B kinase subunit epsilon

rno:04620

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

rno:04620

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Il12a

interleukin 12A

rno:04620

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

Il12b

interleukin 12B

rno:04620

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

interleukin 1 beta

rno:04620

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

interleukin 6

rno:04620

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Irak1

interleukin-1 receptor-associated kinase 1

KEGG
RGD

rno:04620, RGD:5685014

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Irak2

interleukin-1 receptor-associated kinase 2

RGD

RGD:5685014

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

Irak3

interleukin-1 receptor-associated kinase 3

RGD

PMID:28954388

RGD:34888230

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

Irak4

interleukin-1 receptor-associated kinase 4

KEGG
RGD

rno:04620, RGD:5685014

NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837

Irf3

interferon regulatory factor 3

KEGG
RGD

rno:04620, RGD:5685014

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

Irf5

interferon regulatory factor 5

rno:04620

NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267

Irf7

interferon regulatory factor 7

rno:04620

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

Jun proto-oncogene, AP-1 transcription factor subunit

rno:04620

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

Lbp

lipopolysaccharide binding protein

KEGG
RGD

PMID:22119168

rno:04620, RGD:7247704

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

Ly96

lymphocyte antigen 96

PMID:21741580 PMID:22119168

KEGG
RGD

rno:04620, RGD:5685019, RGD:7247704

NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386

mitogen activated protein kinase kinase 1

rno:04620

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

mitogen activated protein kinase kinase 2

rno:04620

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

Map2k3

mitogen activated protein kinase kinase 3

rno:04620

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

Map2k4

mitogen activated protein kinase kinase 4

rno:04620

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

mitogen-activated protein kinase kinase 6