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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:pindolol pharmacodynamics pathway
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Accession:PW:0002264 term browser browse the term
Definition:The pathway of pindolol-target interaction and of the biochemical or physiological responses to drug. The drug is non-selective blocker of adrenergic receptor beta. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00306


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pindolol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00306 NCBI chr 2:41,666,974...41,754,624
Ensembl chr 2:41,666,909...41,754,620 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO SMPDB SMP:00306 NCBI chr 5:51,536,531...51,673,583
Ensembl chr 5:51,536,526...51,691,595 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO SMPDB SMP:00306 NCBI chr14:124,400,330...124,401,739
Ensembl chr14:124,400,330...124,401,739 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO SMPDB SMP:00306 NCBI chr13:88,934,873...88,980,317
Ensembl chr13:88,934,868...88,983,105 		JBrowse link
G ALG10 ALG10 alpha-1,2-glucosyltransferase ISO SMPDB SMP:00306 NCBI chr 5:40,416,335...40,423,026 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00306 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00306 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,341,322...90,370,996 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00306 NCBI chr 6:49,905,851...49,927,437
Ensembl chr 6:49,905,847...49,927,633 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00306 NCBI chr 4:81,912,543...81,937,015
Ensembl chr 4:81,911,561...81,991,840 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00306 NCBI chr12:52,925,697...52,932,638
Ensembl chr12:52,925,693...52,932,635 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00306 NCBI chr13:82,680,442...82,727,052 JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00306 NCBI chr  X:98,514,286...98,535,154
Ensembl chr  X:98,514,305...98,535,149 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO SMPDB SMP:00306 NCBI chr14:31,674,659...31,744,981
Ensembl chr14:31,674,757...31,744,969 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO SMPDB SMP:00306 NCBI chr 5:69,016,954...69,448,428
Ensembl chr 5:69,275,176...69,454,459 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO SMPDB SMP:00306 NCBI chr12:26,838,633...26,912,344
Ensembl chr12:26,844,079...26,912,110 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO SMPDB SMP:00306 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,427...40,695,177 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00306 NCBI chr13:32,845,110...32,988,851
Ensembl chr13:32,845,115...32,988,774 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00306 NCBI chr12:23,038,185...23,060,504
Ensembl chr12:23,037,810...23,060,490 		JBrowse link
G CALM1 calmodulin 1 ISO SMPDB SMP:00306 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,160,806...112,171,744 		JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 ISO SMPDB SMP:00306 NCBI chr17:36,917,276...36,946,232
Ensembl chr17:36,915,953...36,946,187 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO SMPDB SMP:00306 NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,145...12,600,186 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO SMPDB SMP:00306 NCBI chr13:132,819,931...133,084,880
Ensembl chr13:132,820,870...133,086,841 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00306 NCBI chr 9:45,165,314...45,172,440 JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 ISO SMPDB SMP:00306 NCBI chr 7:60,010,396...60,052,258
Ensembl chr 7:60,010,283...60,050,689 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO SMPDB SMP:00306 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,912 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO SMPDB SMP:00306 NCBI chr 5:65,439,336...65,442,207
Ensembl chr 5:65,439,336...65,442,207 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 ISO SMPDB SMP:00306 NCBI chr 4:108,394,687...108,621,514
Ensembl chr 4:108,246,237...108,621,510 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO SMPDB SMP:00306 NCBI chr13:198,051,281...198,059,444
Ensembl chr13:198,051,282...198,059,296 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO SMPDB SMP:00306 NCBI chr13:197,979,749...197,980,974
Ensembl chr13:197,980,145...197,980,516 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO SMPDB SMP:00306 NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111 		JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00306 NCBI chr14:112,857,058...112,876,469
Ensembl chr14:112,857,062...112,876,439 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO SMPDB SMP:00306 NCBI chr 2:41,756,637...41,760,340
Ensembl chr 2:41,757,356...41,765,555 		JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO SMPDB SMP:00306 NCBI chr12:10,351,959...10,380,631
Ensembl chr12:10,351,699...10,362,244 		JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 ISO SMPDB SMP:00306 NCBI chr15:62,263,913...62,415,915
Ensembl chr15:62,264,069...62,413,566 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO SMPDB SMP:00306 NCBI chr 5:9,526,399...9,549,290
Ensembl chr 5:9,547,177...9,548,520 		JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 ISO SMPDB SMP:00306 NCBI chr 9:55,836,777...55,861,288
Ensembl chr 9:55,836,701...55,864,941 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO SMPDB SMP:00306 NCBI chr 5:51,695,927...51,704,402
Ensembl chr 5:51,696,188...51,703,813 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 ISO SMPDB SMP:00306 NCBI chr14:57,268,064...57,319,338
Ensembl chr14:57,265,780...57,318,989 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO SMPDB SMP:00306 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111 		JBrowse link
G MYLK myosin light chain kinase ISO SMPDB SMP:00306 NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00306 NCBI chr17:17,007,197...17,745,314
Ensembl chr17:17,007,261...17,745,313 		JBrowse link
G PLN phospholamban ISO SMPDB SMP:00306 NCBI chr 1:43,449,354...43,458,925
Ensembl chr 1:43,449,354...43,458,925 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO SMPDB SMP:00306 NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO SMPDB SMP:00306 NCBI chr12:11,662,344...11,681,490
Ensembl chr12:11,662,347...11,681,373 		JBrowse link
G RYR2 ryanodine receptor 2 ISO SMPDB SMP:00306 NCBI chr14:53,652,140...54,406,691
Ensembl chr14:53,652,485...54,192,063 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO SMPDB SMP:00306 NCBI chr13:23,336,143...23,424,755
Ensembl chr13:23,336,153...23,424,755 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO SMPDB SMP:00306 NCBI chr 3:99,823,503...100,257,306
Ensembl chr 3:99,897,162...100,244,759 		JBrowse link
G SNTB1 syntrophin beta 1 ISO SMPDB SMP:00306 NCBI chr 4:18,288,756...18,524,362
Ensembl chr 4:18,288,843...18,526,215 		JBrowse link
G SNTB2 syntrophin beta 2 ISO SMPDB SMP:00306 NCBI chr 6:17,674,587...17,774,550
Ensembl chr 6:17,681,837...17,774,527 		JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type ISO SMPDB SMP:00306 NCBI chr13:34,591,571...34,594,320
Ensembl chr13:34,591,386...34,594,337 		JBrowse link
G TNNC2 troponin C2, fast skeletal type ISO SMPDB SMP:00306 NCBI chr17:48,025,621...48,026,762
Ensembl chr17:48,024,687...48,028,651 		JBrowse link
G TNNI1 troponin I1, slow skeletal type ISO SMPDB SMP:00306 NCBI chr10:23,788,279...23,800,554
Ensembl chr10:23,788,279...23,804,119 		JBrowse link
G TNNI2 troponin I2, fast skeletal type ISO SMPDB SMP:00306 NCBI chr 2:1,251,566...1,253,883
Ensembl chr 2:1,251,527...1,253,893 		JBrowse link
G TNNI3 troponin I3, cardiac type ISO SMPDB SMP:00306 NCBI chr 6:59,366,828...59,377,490
Ensembl chr 6:59,371,080...59,377,734
Ensembl chr 6:59,371,080...59,377,734 		JBrowse link
G TNNT1 troponin T1, slow skeletal type ISO SMPDB SMP:00306 NCBI chr 6:59,351,445...59,365,584
Ensembl chr 6:59,347,582...59,365,284 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO SMPDB SMP:00306 NCBI chr10:23,749,528...23,759,696
Ensembl chr10:23,749,335...23,763,396 		JBrowse link
G TNNT3 troponin T3, fast skeletal type ISO SMPDB SMP:00306 NCBI chr 2:1,297,826...1,316,865
Ensembl chr 2:1,299,174...1,316,517 		JBrowse link
G TPM1 tropomyosin 1 ISO SMPDB SMP:00306 NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,986...109,020,035 		JBrowse link
G TPM2 tropomyosin 2 ISO SMPDB SMP:00306 NCBI chr 1:236,402,249...236,410,390
Ensembl chr 1:236,402,251...236,410,905 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4041
    drug pathway 384
      cardiovascular system drug pathway 178
        adrenergic beta receptor antagonist drug pathway 60
          adrenergic beta receptor non-selective antagonist drug pathway 60
            pindolol drug pathway 59
              pindolol pharmacodynamics pathway 59
paths to the root