decreased circulating CCL3 level - Ontology Report

Advanced Search (OLGA)

MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	decreased circulating CCL3 level	go back to main search page
Accession:	MP:0031250	browse the term
Definition:	reduction in the blood levels of CCL3 protein, a chemokine that is secreted by a variety of hematopoietic and non-hematopoietic cells upon stimulation and plays a key role in recruiting inflammatory cells (macrophages, lymphocytes, eosinophils and basophils) to sites of injury or inflammation via the CCR1 or CCR5 receptor; it helps promote wound healing by recruiting macrophages to sites of tissue injury; acts as a potent osteoclast activator and induces bone resorption; exerts HIV-suppressive activity; and inhibits hematopoietic stem cell proliferation
Synonyms:	exact_synonym:	decreased circulating C-C motif chemokine 3 level; decreased circulating MIP-1 alpha level; decreased circulating MIP-1alpha level; decreased circulating MIP1-alpha level; decreased circulating MIP1A level; decreased circulating macrophage inflammatory protein 1-alpha level; reduced circulating C-C motif chemokine 3 level; reduced circulating MIP-1 alpha level; reduced circulating MIP-1alpha level; reduced circulating MIP1-alpha level; reduced circulating MIP1A level; reduced circulating macrophage inflammatory protein 1-alpha level

show annotations for term's descendants Sort by:
Rat (0) Mouse (1) Human (0) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All

0 Annotations Found

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5420
immune system phenotype	519
abnormal immune system physiology	384
abnormal immune serum protein physiology	92
abnormal cytokine level	39
abnormal chemokine level	7
abnormal circulating chemokine level	6
decreased circulating chemokine level	0
decreased circulating CCL3 level	0
Path 2
Term	Annotations
mammalian phenotype	5420
homeostasis/metabolism phenotype	1426
abnormal homeostasis	1327
abnormal protein level	137
abnormal intercellular signaling peptide or protein level	43
abnormal cytokine level	39
abnormal chemokine level	7
decreased chemokine level	0
decreased CCL3 level	0
decreased circulating CCL3 level	0

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message