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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating angiotensin II level
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Accession:MP:0031232 term browser browse the term
Definition:increased concentration in the blood of angiotensin II, a vasoactive octapeptide produced by the action of angiotensin-converting enzyme on angiotensin I; it acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone
Synonyms:exact_synonym: elevated circulating angiotensin II level
 narrow_synonym: increased plasma angiotensin II level;   increased serum angiotensin II level


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  mammalian phenotype 5422
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal hormone level 324
          abnormal circulating hormone level 293
            increased circulating hormone level 194
              increased circulating angiotensin II level 0
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