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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased CXCL10 level
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Accession:MP:0031226 term browser browse the term
Definition:increase in the amount of CXCL10 protein, a pro-inflammatory cytokine that is secreted by a wide range of cell types in response to interferon-gamma, and produces its effects by binding to the cell surface chemokine receptor CXCR3
Synonyms:exact_synonym: elevated CXCL10 level;   increased C-X-C motif chemokine ligand 10 level;   increased IFN gamma-inducible protein 10 level;   increased IP-10 level;   increased IP10 level;   increased gamma-IP10 level;   increased interferon gamma-induced protein 10 level;   increased small-inducible cytokine B10 level



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    immune system phenotype 519
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal chemokine level 7
              increased chemokine level 3
                increased CXCL10 level 0
                  increased circulating CXCL10 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal chemokine level 7
                increased chemokine level 3
                  increased CXCL10 level 0
                    increased circulating CXCL10 level 0
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