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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal circulating myoglobin level
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Accession:MP:0031107 term browser browse the term
Definition:anomaly in the blood level of myoglobin, a low molecular weight oxygen binding heme protein that is normally found exclusively in heart and skeletal muscle cells; in blood, myoglobin is bound primarily to plasma globulins, a complex which is filtered by the kidneys; if the plasma concentration exceeds the plasma binding capacity, myoglobin begins to appear in the urine; monitoring myoglobin levels in blood (and urine) has been used as a means to detect skeletal or cardiac muscle cell injury


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abnormal circulating myoglobin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667 		JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
increased circulating myoglobin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il36rn interleukin 36 receptor antagonist IMP RGD PMID:32048631 RGD:126925167 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Il36rntm1(Myh6-cre)Mhzh interleukin 36 receptor antagonist; tm1, Mhzh IMP RGD PMID:32048631 RGD:126925167
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  mammalian phenotype 5418
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal blood homeostasis 761
          abnormal circulating protein level 109
            abnormal circulating myoglobin level 6
              decreased circulating myoglobin level 0
              increased circulating myoglobin level 3
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