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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to Riboviria infection induced morbidity/mortality
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Accession:MP:0031024 term browser browse the term
Definition:increased likelihood that an organism will display the expected moribund state caused by a Riboviria iinfection or from components of or toxins produced by a virus from this Realm
Synonyms:exact_synonym: decreased resistance to Riboviria infection induced morbidity/mortality;   increased sensitivity to Riboviria infection induced morbidity/mortality



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increased susceptibility to Riboviria infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cimap2 ciliary microtubule associated protein 2 IAGP MGI PMID:25883318 NCBI chr 4:106,448,105...106,474,594
Ensembl chr 4:106,448,106...106,474,438
JBrowse link
G Ddx60 DExD/H box helicase 60 IAGP MGI PMID:25981042 NCBI chr 8:62,381,155...62,491,278
Ensembl chr 8:62,381,121...62,491,278
JBrowse link
G Gsdmd gasdermin D IAGP MGI PMID:28636595 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
JBrowse link
G Ifit1 interferon-induced protein with tetratricopeptide repeats 1 IAGP MGI PMID:21642987 NCBI chr19:34,618,289...34,627,409
Ensembl chr19:34,618,271...34,627,409
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 IAGP MGI PMID:22615570 NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:8456301 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Lrrc55os leucine rich repeat containing 55, opposite strand IAGP MGI PMID:31213650 Ensembl chr 2:84,923,589...85,038,236 JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:29101251 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mavs mitochondrial antiviral signaling protein IAGP MGI PMID:25981042 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945
JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 IAGP MGI PMID:35792897 NCBI chr 1:36,303,683...36,313,755
Ensembl chr 1:36,303,678...36,313,760
JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 IAGP MGI PMID:28636595 NCBI chr 7:140,500,777...140,509,105
Ensembl chr 7:140,500,815...140,509,105
JBrowse link
G Nlrp9b NLR family, pyrin domain containing 9B IAGP MGI PMID:28636595 NCBI chr 7:19,725,318...19,796,867
Ensembl chr 7:19,725,390...19,807,231
JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 IAGP MGI PMID:29101251 NCBI chr 8:26,091,617...26,209,694
Ensembl chr 8:26,091,617...26,209,694
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:15069016 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Sfn stratifin IAGP MGI PMID:21205887 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
JBrowse link
G Trim41 tripartite motif-containing 41 IAGP MGI PMID:33640899 NCBI chr11:48,697,230...48,709,026
Ensembl chr11:48,697,231...48,708,180
JBrowse link
G Tyk2 tyrosine kinase 2 IAGP MGI PMID:22723949 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539
JBrowse link
G Ubl7 ubiquitin-like 7 (bone marrow stromal cell-derived) IAGP MGI PMID:36943869 NCBI chr 9:57,818,280...57,837,624
Ensembl chr 9:57,818,262...57,837,251
JBrowse link
G Zup1 zinc finger containing ubiquitin peptidase 1 IAGP MGI PMID:38460305 NCBI chr10:33,795,138...33,827,316
Ensembl chr10:33,795,138...33,827,265
JBrowse link
increased susceptibility to Coronaviridae infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr1 C-C motif chemokine receptor 1 IAGP MGI PMID:19079579 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IAGP MGI PMID:11591787 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:32704094 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351
JBrowse link
G Dpp4 dipeptidylpeptidase 4 IAGP MGI PMID:27892925 PMID:28348219 NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 IAGP MGI PMID:23102608 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022
JBrowse link
G Egfr epidermal growth factor receptor IAGP MGI PMID:28404843 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Ifit1 interferon-induced protein with tetratricopeptide repeats 1 IAGP MGI PMID:24198415 NCBI chr19:34,618,289...34,627,409
Ensembl chr19:34,618,271...34,627,409
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:16985170 PMID:26867177 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
G Ifng interferon gamma IAGP MGI PMID:9765476 PMID:9973424 PMID:11864749 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ly6e lymphocyte antigen 6 family member E IAGP MGI PMID:32704094 NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752
JBrowse link
G Muc4 mucin 4 IEA MGI NCBI chr16:32,555,089...32,602,786
Ensembl chr16:32,555,015...32,602,754
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:19079579 PMID:26136579 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Plat plasminogen activator, tissue IAGP MGI PMID:23919993 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Ptgdr prostaglandin D receptor IAGP MGI PMID:28630327 NCBI chr14:45,088,692...45,096,832
Ensembl chr14:45,088,692...45,096,832
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 IAGP MGI PMID:23919993 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IAGP MGI PMID:20386712 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 IAGP MGI PMID:26015500 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786
JBrowse link
increased susceptibility to Flaviviridae infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase IAGP MGI PMID:24284630 NCBI chr 9:78,337,800...78,350,519
Ensembl chr 9:78,337,808...78,350,519
JBrowse link
G Dhx58 DExH-box helicase 58 IAGP MGI PMID:22841161 NCBI chr11:100,585,710...100,595,165
Ensembl chr11:100,585,710...100,595,097
JBrowse link
G Il34 interleukin 34 IAGP MGI PMID:22729249 NCBI chr 8:111,467,809...111,532,579
Ensembl chr 8:111,468,461...111,532,556
JBrowse link
G Mavs mitochondrial antiviral signaling protein IAGP MGI PMID:20140199 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945
JBrowse link
G Rigi RNA sensor RIG-I IAGP MGI PMID:16625202 NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Sarm1 sterile alpha and HEAT/Armadillo motif containing 1 IAGP MGI PMID:19587044 NCBI chr11:78,361,099...78,388,642
Ensembl chr11:78,363,156...78,388,580
JBrowse link
G Selenok selenoprotein K IAGP MGI PMID:21220695 NCBI chr14:29,690,337...29,697,031
Ensembl chr14:29,690,265...29,697,619
JBrowse link
G Stat2 signal transducer and activator of transcription 2 IAGP MGI PMID:29746837 NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718
JBrowse link
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 IAGP MGI PMID:24800825 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Bpifa1 BPI fold containing family A, member 1 IAGP MGI PMID:28513596 NCBI chr 2:153,984,800...153,991,137
Ensembl chr 2:153,984,800...153,991,139
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B IAGP MGI PMID:34566982 NCBI chr15:101,982,208...102,005,608
Ensembl chr15:101,982,208...102,005,608
JBrowse link
G Hcfc2 host cell factor C2 IAGP MGI PMID:28970238 NCBI chr10:82,534,841...82,631,699
Ensembl chr10:82,531,994...82,578,262
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 IAGP MGI PMID:22446628 NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:26867177 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
G Il36g interleukin 36G IAGP MGI PMID:29848754 NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580
JBrowse link
G Irf7 interferon regulatory factor 7 IAGP MGI PMID:26329040 NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
JBrowse link
G Lst1 leukocyte specific transcript 1 IAGP MGI PMID:26817701 NCBI chr17:35,404,071...35,407,416
Ensembl chr17:35,404,071...35,407,415
JBrowse link
G Mx1 MX dynamin-like GTPase 1 IAGP MGI PMID:7884909 NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107
JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 IAGP MGI PMID:16565719 NCBI chr 7:4,340,714...4,348,183
Ensembl chr 7:4,340,723...4,348,163
JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 IAGP MGI PMID:34566982 NCBI chr 2:25,134,825...25,145,458
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034
JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 IAGP MGI PMID:28513596 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322
JBrowse link
G Sertad3 SERTA domain containing 3 IAGP MGI PMID:33147462 NCBI chr 7:27,173,265...27,176,789
Ensembl chr 7:27,173,193...27,176,789
JBrowse link
G Socs4 suppressor of cytokine signaling 4 IAGP MGI PMID:24809749 NCBI chr14:47,514,377...47,533,559
Ensembl chr14:47,514,388...47,533,559
JBrowse link
G Trim35 tripartite motif-containing 35 IAGP MGI PMID:32562145 NCBI chr14:66,534,474...66,548,873
Ensembl chr14:66,534,480...66,548,873
JBrowse link
G Ubl7 ubiquitin-like 7 (bone marrow stromal cell-derived) IAGP MGI PMID:36943869 NCBI chr 9:57,818,280...57,837,624
Ensembl chr 9:57,818,262...57,837,251
JBrowse link
G Zup1 zinc finger containing ubiquitin peptidase 1 IAGP MGI PMID:38460305 NCBI chr10:33,795,138...33,827,316
Ensembl chr10:33,795,138...33,827,265
JBrowse link
increased susceptibility to Paramyxoviridae infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:9696838 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
increased susceptibility to Picornaviridae infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx58 DExH-box helicase 58 IAGP MGI PMID:20080593 NCBI chr11:100,585,710...100,595,165
Ensembl chr11:100,585,710...100,595,097
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:32814047 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:7479980 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:18332263 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Stat2 signal transducer and activator of transcription 2 IAGP MGI PMID:19272190 NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 IAGP MGI PMID:21239721 PMID:21998457 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786
JBrowse link
G Tlr3 toll-like receptor 3 IAGP MGI PMID:16936008 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
JBrowse link
G Trim65 tripartite motif-containing 65 IAGP MGI PMID:28031478 NCBI chr11:116,008,015...116,022,239
Ensembl chr11:116,012,672...116,021,954
JBrowse link
G Tyk2 tyrosine kinase 2 IAGP MGI PMID:22723949 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539
JBrowse link
increased susceptibility to Togaviridae infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:7479980 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17090
    mortality/aging 6878
      abnormal induced morbidity/mortality 846
        abnormal susceptibility to infection induced morbidity/mortality 298
          increased susceptibility to infection induced morbidity/mortality 215
            increased susceptibility to viral infection induced morbidity/mortality 88
              increased susceptibility to Riboviria infection induced morbidity/mortality 61
                increased susceptibility to Coronaviridae infection induced morbidity/mortality 17
                increased susceptibility to Flaviviridae infection induced morbidity/mortality 8
                increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality 18
                increased susceptibility to Paramyxoviridae infection induced morbidity/mortality 1
                increased susceptibility to Picornaviridae infection induced morbidity/mortality 9
                increased susceptibility to Togaviridae infection induced morbidity/mortality 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 17090
    immune system phenotype 5776
      abnormal immune system physiology 3513
        abnormal response to antigen 885
          abnormal response to infection 875
            abnormal susceptibility to infection 830
              increased susceptibility to infection 600
                increased susceptibility to viral infection 199
                  increased susceptibility to viral infection induced morbidity/mortality 88
                    increased susceptibility to Riboviria infection induced morbidity/mortality 61
                      increased susceptibility to Coronaviridae infection induced morbidity/mortality 17
                      increased susceptibility to Flaviviridae infection induced morbidity/mortality 8
                      increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality 18
                      increased susceptibility to Paramyxoviridae infection induced morbidity/mortality 1
                      increased susceptibility to Picornaviridae infection induced morbidity/mortality 9
                      increased susceptibility to Togaviridae infection induced morbidity/mortality 1
paths to the root