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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:premature ovarian failure
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Accession:MP:0031020 term browser browse the term
Definition:cessation of ovarian function occurring at an earlier than expected age
Synonyms:exact_synonym: accelerated loss of ovarian function;   early cessation of ovarian function;   precocious ovarian failure;   primary ovarian insufficiency
 xref: EFO:0004266

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premature ovarian failure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amhr2 anti-Mullerian hormone type 2 receptor IAGP MGI PMID:18809571 PMID:22128018 NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068
JBrowse link
G C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 IAGP MGI PMID:21239444 NCBI chr 6:7,845,224...7,872,042
Ensembl chr 6:7,844,842...7,875,687
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 IAGP MGI PMID:34930897 NCBI chr19:36,996,742...37,185,018
Ensembl chr19:36,998,691...37,186,000
JBrowse link
G Csnk2b casein kinase 2, beta polypeptide IAGP MGI PMID:29725001 NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029
JBrowse link
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 IAGP MGI PMID:15710898 NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 IAGP MGI PMID:30283081 NCBI chr15:38,976,300...39,010,251
Ensembl chr15:38,976,260...39,010,251
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit IAGP MGI PMID:26083875 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Kif18a kinesin family member 18A IAGP MGI PMID:16822657 NCBI chr 2:109,111,165...109,172,094
Ensembl chr 2:109,111,083...109,172,092
JBrowse link
G Lhx8 LIM homeobox protein 8 IAGP MGI PMID:29329412 NCBI chr 3:154,011,925...154,036,190
Ensembl chr 3:154,011,931...154,036,296
JBrowse link
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor IAGP MGI PMID:21987787 NCBI chr10:53,412,411...53,507,251
Ensembl chr10:53,412,411...53,506,535
JBrowse link
G Mgat1 mannoside acetylglucosaminyltransferase 1 IAGP MGI PMID:21239444 NCBI chr11:49,135,018...49,153,854
Ensembl chr11:49,135,018...49,153,857
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:18239123 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Rps26 ribosomal protein S26 IAGP MGI PMID:30451825 NCBI chr10:128,460,398...128,462,375
Ensembl chr10:128,460,403...128,462,616
JBrowse link
G Smad2 SMAD family member 2 IAGP MGI PMID:18809571 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:18809571 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Taf4b TATA-box binding protein associated factor 4b IAGP MGI PMID:19684329 NCBI chr18:14,916,302...15,035,160
Ensembl chr18:14,916,302...15,033,416
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 IAGP MGI PMID:29467381 NCBI chr 1:167,136,239...167,161,547
Ensembl chr 1:167,135,947...167,161,547
JBrowse link
G Tsc1 TSC complex subunit 1 IAGP MGI PMID:19843540 PMID:22128018 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16659
    mortality/aging 6775
      premature aging 104
        early reproductive senescence 56
          premature ovarian failure 18
Path 2
Term Annotations click to browse term
  mammalian phenotype 16659
    endocrine/exocrine gland phenotype 3401
      abnormal gland physiology 907
        abnormal sex gland physiology 200
          abnormal female reproductive gland physiology 94
            abnormal ovary physiology 94
              premature ovarian failure 18
paths to the root