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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:brain lesion
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Accession:MP:0021002 term browser browse the term
Definition:focal pathological changes characterized by alteration in the size, shape and organization of the cellular components of the brain tissue
Synonyms:narrow_synonym: cerebral lesion


show annotations for term's descendants           Sort by:
brain lesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a1 collagen, type IV, alpha 1 IAGP MGI PMID:15905400 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G Notch3 notch 3 IAGP MGI PMID:21940951 NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826 		JBrowse link
G Serac1 serine active site containing 1 IAGP MGI PMID:35235340 NCBI chr17:6,090,846...6,130,064
Ensembl chr17:6,092,471...6,130,016 		JBrowse link
G Spta1 spectrin alpha, erythrocytic 1 IAGP MGI PMID:9373273 NCBI chr 1:174,000,305...174,076,015
Ensembl chr 1:174,000,342...174,076,016 		JBrowse link
G Sptb spectrin beta, erythrocytic IAGP MGI PMID:9373273 NCBI chr12:76,627,262...76,757,321
Ensembl chr12:76,627,262...76,757,321 		JBrowse link
G Stmn1 stathmin 1 IAGP MGI PMID:11839567 NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154 		JBrowse link
G Vac14 Vac14 homolog (S. cerevisiae) IAGP MGI PMID:17956977 NCBI chr 8:111,345,161...111,447,030
Ensembl chr 8:111,345,217...111,447,030 		JBrowse link
brain vacuoles term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspa aspartoacylase IAGP MGI PMID:18987190 PMID:24682784 PMID:26511242 PMID:38282243 NCBI chr11:73,195,813...73,217,677
Ensembl chr11:73,195,818...73,220,422 		JBrowse link
G Atp8a2 ATPase, aminophospholipid transporter-like, class I, type 8A, member 2 IEA MGI NCBI chr14:59,884,980...60,324,363
Ensembl chr14:59,875,989...60,434,628 		JBrowse link
G Atrn attractin IAGP MGI PMID:11444801 PMID:11514456 PMID:12560552 PMID:18064672 PMID:18821597 NCBI chr 2:130,734,363...130,872,249
Ensembl chr 2:130,748,415...130,872,253 		JBrowse link
G Atrnl1 attractin like 1 IAGP MGI PMID:18064672 NCBI chr19:57,599,248...58,121,775
Ensembl chr19:57,599,466...58,121,775 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 IAGP MGI PMID:15710896 NCBI chr10:127,001,025...127,008,209
Ensembl chr10:127,001,094...127,008,199 		JBrowse link
G Clcc1 chloride channel CLIC-like 1 IAGP MGI PMID:25698737 NCBI chr 3:108,561,194...108,586,156
Ensembl chr 3:108,561,229...108,586,156 		JBrowse link
G Clcn2 chloride channel, voltage-sensitive 2 IAGP MGI PMID:17567819 PMID:20071672 PMID:24647135 PMID:28859131 PMID:31727896 NCBI chr16:20,521,185...20,536,496
Ensembl chr16:20,521,714...20,536,496 		JBrowse link
G Coq9 coenzyme Q9 IAGP MGI PMID:23255162 NCBI chr 8:95,565,041...95,581,523
Ensembl chr 8:95,564,949...95,581,523 		JBrowse link
G Dnajc11 DnaJ heat shock protein family (Hsp40) member C11 IAGP MGI PMID:25111180 NCBI chr 4:152,018,177...152,066,416
Ensembl chr 4:152,018,148...152,066,594 		JBrowse link
G Ei24 etoposide induced 2.4 mRNA IAGP MGI PMID:23074225 NCBI chr 9:36,690,449...36,708,630
Ensembl chr 9:36,690,455...36,708,689 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B, subunit 4 delta IAGP MGI PMID:26974157 NCBI chr 5:31,344,902...31,350,483
Ensembl chr 5:31,344,902...31,350,774 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B, subunit 5 epsilon IAGP MGI PMID:26974157 NCBI chr16:20,317,544...20,328,073
Ensembl chr16:20,317,567...20,328,073 		JBrowse link
G Fuca1 fucosidase, alpha-L- 1, tissue IAGP MGI PMID:27491075 NCBI chr 4:135,648,037...135,667,611
Ensembl chr 4:135,648,046...135,667,622 		JBrowse link
G Hepacam hepatocyte cell adhesion molecule IAGP MGI PMID:24647135 PMID:28695146 NCBI chr 9:37,278,652...37,297,868
Ensembl chr 9:37,278,647...37,297,871 		JBrowse link
G Hltf helicase-like transcription factor IAGP MGI PMID:23826137 NCBI chr 3:20,111,959...20,172,655
Ensembl chr 3:20,111,975...20,172,654 		JBrowse link
G Ids iduronate 2-sulfatase IAGP MGI PMID:22704483 NCBI chr  X:69,386,675...69,429,437
Ensembl chr  X:69,386,675...69,408,690 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IAGP MGI PMID:17942730 NCBI chr 1:172,168,777...172,201,652
Ensembl chr 1:172,168,777...172,201,652 		JBrowse link
G Lynx1 Ly6/neurotoxin 1 IAGP MGI PMID:16950157 NCBI chr15:74,619,705...74,624,828
Ensembl chr15:74,619,701...74,624,895 		JBrowse link
G Man2c1 mannosidase, alpha, class 2C, member 1 IAGP MGI PMID:24550399 NCBI chr 9:57,037,953...57,049,497
Ensembl chr 9:57,037,974...57,050,006 		JBrowse link
G Mgrn1 mahogunin, ring finger 1 IAGP MGI PMID:12560552 NCBI chr16:4,703,964...4,756,160
Ensembl chr16:4,704,113...4,756,160 		JBrowse link
G Mlc1 megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human) IAGP MGI PMID:24647135 PMID:25382142 PMID:27748972 PMID:28695146 NCBI chr15:88,840,087...88,863,192
Ensembl chr15:88,840,087...88,863,210 		JBrowse link
G Mrpl3 mitochondrial ribosomal protein L3 IAGP MGI PMID:21217823 NCBI chr 9:104,930,394...104,954,665
Ensembl chr 9:104,930,438...104,957,087 		JBrowse link
G Nat8l N-acetyltransferase 8-like IAGP MGI PMID:26511242 NCBI chr 5:34,153,328...34,163,260
Ensembl chr 5:34,153,328...34,163,260 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 IAGP MGI PMID:24589777 NCBI chr 2:25,134,825...25,145,458
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 IAGP MGI PMID:20534480 PMID:22653057 NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794 		JBrowse link
G Pde4b phosphodiesterase 4B, cAMP specific IEA MGI NCBI chr 4:101,944,529...102,464,459
Ensembl chr 4:101,944,740...102,464,456 		JBrowse link
G Pde6a phosphodiesterase 6A, cGMP-specific, rod, alpha IEA MGI NCBI chr18:61,353,546...61,426,698
Ensembl chr18:61,353,387...61,422,995 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IEA MGI NCBI chr11:59,861,440...59,937,394
Ensembl chr11:59,861,440...59,937,315 		JBrowse link
G Pepd peptidase D IAGP MGI PMID:18821597 NCBI chr 7:34,611,832...34,744,131
Ensembl chr 7:34,611,804...34,744,133 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing IAGP MGI PMID:23047693 NCBI chr 1:65,225,796...65,317,855
Ensembl chr 1:65,225,842...65,317,854 		JBrowse link
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit IAGP MGI PMID:19217427 NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IAGP MGI PMID:17412759 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Prnp prion protein IAGP MGI PMID:19675240 PMID:19709627 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349 		JBrowse link
G Slc13a3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 IAGP MGI PMID:38282243 NCBI chr 2:165,247,215...165,315,117
Ensembl chr 2:165,246,948...165,315,150 		JBrowse link
G Slc17a5 solute carrier family 17 (anion/sugar transporter), member 5 IAGP MGI PMID:20007460 NCBI chr 9:78,443,769...78,495,346
Ensembl chr 9:78,443,770...78,495,323 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial IAGP MGI PMID:9462746 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sox10 SRY (sex determining region Y)-box 10 IAGP MGI PMID:25399070 NCBI chr15:79,039,113...79,048,690
Ensembl chr15:79,039,108...79,049,440 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B IAGP MGI PMID:26438849 NCBI chr 3:69,726,871...69,768,697
Ensembl chr 3:69,726,875...69,767,273 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 IAGP MGI PMID:15710896 NCBI chr 6:72,074,555...72,131,555
Ensembl chr 6:72,074,576...72,131,555 		JBrowse link
G Tymp thymidine phosphorylase IAGP MGI PMID:19028666 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Upp1 uridine phosphorylase 1 IAGP MGI PMID:19028666 NCBI chr11:9,068,008...9,086,170
Ensembl chr11:9,068,103...9,086,170 		JBrowse link
G Wdr45 WD repeat domain 45 IAGP MGI PMID:26000824 NCBI chr  X:7,588,212...7,594,439
Ensembl chr  X:7,580,572...7,594,445 		JBrowse link
G Zfp597 zinc finger protein 597 IAGP MGI PMID:19968752 NCBI chr16:3,679,408...3,702,241
Ensembl chr16:3,676,185...3,702,425 		JBrowse link
cerebral infarct term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spta1 spectrin alpha, erythrocytic 1 IAGP MGI PMID:9373273 NCBI chr 1:174,000,305...174,076,015
Ensembl chr 1:174,000,342...174,076,016 		JBrowse link
G Sptb spectrin beta, erythrocytic IAGP MGI PMID:9373273 NCBI chr12:76,627,262...76,757,321
Ensembl chr12:76,627,262...76,757,321 		JBrowse link
neurofibrillary tangles term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arcn1 archain 1 IAGP MGI PMID:20502676 NCBI chr 9:44,653,440...44,679,105
Ensembl chr 9:44,652,861...44,679,142 		JBrowse link
G Fgf14 fibroblast growth factor 14 IAGP MGI PMID:16020737 PMID:16291936 PMID:24503275 NCBI chr14:124,211,257...124,915,098
Ensembl chr14:124,215,319...124,914,539 		JBrowse link
G Hspa4 heat shock protein 4 IAGP MGI PMID:20679486 NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284 		JBrowse link
G Immt inner membrane protein, mitochondrial IAGP MGI PMID:36974636 NCBI chr 6:71,806,200...71,852,250
Ensembl chr 6:71,808,315...71,854,372 		JBrowse link
G Mapt microtubule-associated protein tau IAGP MGI PMID:21281813 PMID:21573167 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916 		JBrowse link
G Psen1 presenilin 1 IAGP MGI PMID:16282321 PMID:16377636 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
tau protein deposits term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein IAGP MGI PMID:24278307 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
G Cav1 caveolin 1, caveolae protein IAGP MGI PMID:21203469 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
G Fgf14 fibroblast growth factor 14 IAGP MGI PMID:16291936 PMID:24503275 NCBI chr14:124,211,257...124,915,098
Ensembl chr14:124,215,319...124,914,539 		JBrowse link
G Grn granulin IAGP MGI PMID:29382817 NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874 		JBrowse link
G Hspa4 heat shock protein 4 IAGP MGI PMID:20679486 NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284 		JBrowse link
G Il33 interleukin 33 IAGP MGI PMID:28675392 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Khdrbs2 KH domain containing, RNA binding, signal transduction associated 2 IAGP MGI PMID:19503083 NCBI chr 1:32,211,683...32,744,305
Ensembl chr 1:32,211,795...32,697,649 		JBrowse link
G Klc1 kinesin light chain 1 IAGP MGI PMID:19420244 NCBI chr12:111,724,869...111,774,278
Ensembl chr12:111,725,283...111,774,278 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IAGP MGI PMID:25836420 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323 		JBrowse link
G Mapt microtubule-associated protein tau IAGP MGI PMID:12859672 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IAGP MGI PMID:18272675 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IAGP MGI PMID:17623040 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Psen1 presenilin 1 IAGP MGI PMID:16377636 PMID:24278307 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing IAGP MGI PMID:22986780 NCBI chr 9:41,876,005...42,035,593
Ensembl chr 9:41,876,016...42,035,593 		JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 IAGP MGI PMID:16111477 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17059
    nervous system phenotype 4634
      abnormal nervous system morphology 3661
        abnormal brain morphology 2179
          brain lesion 72
            amygdala microinfarct 0
            brain vacuoles 43
            cerebral infarct + 2
            neurofibrillary tangles 6
            tau protein deposits 16
paths to the root