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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased NAD(P)H oxidase activity
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Accession:MP:0020447 term browser browse the term
Definition:reduced ability to catalyze the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide
Synonyms:exact_synonym: decreased NAD(P)H:oxygen oxidoreductase activity;   decreased dual oxidase activity;   reduced NAD(P)H oxidase activity



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decreased NAD(P)H oxidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain IAGP DNA:deletion:splice junction: RGD PMID:19406829 RGD:11040542 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybam1Sdi cytochrome b-245 alpha chain;mutant 1,Sdi IAGP DNA:deletion:splice junction: RGD PMID:19406829 RGD:11040542
G Ncf2 neutrophil cytosolic factor 2 induces IMP compared to wild-type littermates RGD PMID:22326221 PMID:22326221 RGD:9587793, RGD:9587793 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ncf2em1Mcwi neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1,Mcwi induces IMP compared to wild-type littermates RGD PMID:22326221 PMID:22326221 RGD:9587793, RGD:9587793

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  mammalian phenotype 5402
    homeostasis/metabolism phenotype 1418
      abnormal metabolism 75
        abnormal enzyme/coenzyme activity 34
          abnormal NAD(P)H oxidase activity 8
            decreased NAD(P)H oxidase activity 7
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