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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal blood vessel lumen formation
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Accession:MP:0020373 term browser browse the term
Definition:any anomaly in the process in which a developing blood vessel forms an endothelial lumen through which blood will flow; in vertebrates, the lumen of all blood vessels is lined and formed by endothelial cells; in both vasculogenesis and angiogenesis, lumen formation takes place in a cord of endothelial cells and involves a complex mechanism composed of endothelial cell repulsion at the cell-cell contacts within the endothelial cell cords, junctional rearrangement, and endothelial cell shape change
Synonyms:exact_synonym: abnormal blood vessel lumenization


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  mammalian phenotype 5420
    cardiovascular system phenotype 1371
      abnormal cardiovascular system morphology 427
        abnormal cardiovascular development 12
          abnormal vascular development 12
            abnormal blood vessel lumen formation 0
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