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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal mast cell number
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Accession:MP:0020203 term browser browse the term
Definition:an anomaly in the number of the cells that are found in almost all tissues, containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation


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absent mast cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpa3 carboxypeptidase A3, mast cell IAGP MGI PMID:22101159 PMID:25843682 NCBI chr 3:20,269,780...20,296,373
Ensembl chr 3:20,269,784...20,296,345 		JBrowse link
G Fbn1 fibrillin 1 IAGP MGI PMID:7704626 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 IAGP MGI PMID:25843682 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IAGP MGI PMID:25843682 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:7704626 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A IAGP MGI PMID:12714518 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B IAGP MGI PMID:12714518 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
cutaneous mastocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts14 ADAM metallopeptidase with thrombospondin type 1 motif 14 IAGP MGI PMID:29649548 NCBI chr10:61,032,886...61,109,447
Ensembl chr10:61,032,891...61,109,217 		JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif 2 IAGP MGI PMID:29649548 NCBI chr11:50,492,912...50,698,400
Ensembl chr11:50,492,911...50,698,400 		JBrowse link
G Ctnnb1 catenin beta 1 IAGP MGI PMID:24315444 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Dsg3 desmoglein 3 IAGP MGI PMID:8182278 NCBI chr18:20,643,331...20,674,367
Ensembl chr18:20,643,331...20,680,516 		JBrowse link
G Krt14 keratin 14 IAGP MGI PMID:23918954 NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 IAGP MGI PMID:15235600 NCBI chr 5:130,200,644...130,243,178
Ensembl chr 5:130,200,639...130,243,183 		JBrowse link
G Sharpin SHANK-associated RH domain interacting protein IAGP MGI PMID:8362989 PMID:8774148 NCBI chr15:76,231,240...76,235,310
Ensembl chr15:76,231,240...76,235,311 		JBrowse link
G Wls wntless WNT ligand secretion mediator IAGP MGI PMID:23918954 PMID:24315444 NCBI chr 3:159,545,287...159,644,302
Ensembl chr 3:159,545,309...159,644,300 		JBrowse link
decreased mast cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement component 3 IAGP MGI PMID:9367154 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 IAGP MGI PMID:15517609 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729 		JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:19204665 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Gab2 growth factor receptor bound protein 2-associated protein 2 IAGP MGI PMID:11449275 PMID:11861309 PMID:21653832 NCBI chr 7:96,730,958...96,958,158
Ensembl chr 7:96,730,793...96,958,153 		JBrowse link
G Hdc histidine decarboxylase IAGP MGI PMID:11478947 NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219 		JBrowse link
G Itgb7 integrin beta 7 IAGP MGI PMID:10898502 NCBI chr15:102,124,429...102,141,840
Ensembl chr15:102,124,430...102,140,379 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:7683920 PMID:8605335 PMID:10716931 PMID:15024050 PMID:15067126 More... NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kitl kit ligand IAGP MGI PMID:367470 PMID:8605335 PMID:9751763 PMID:19874813 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IAGP MGI PMID:16640660 NCBI chr11:103,110,590...103,158,227
Ensembl chr11:103,110,588...103,158,298 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 IAGP MGI PMID:22001390 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mitf melanogenesis associated transcription factor IAGP MGI PMID:6127714 NCBI chr 6:97,783,966...97,998,321
Ensembl chr 6:97,784,013...97,998,310 		JBrowse link
G Ndst2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 IAGP MGI PMID:10466727 NCBI chr14:20,773,798...20,784,638
Ensembl chr14:20,773,798...20,784,630 		JBrowse link
G Nfatc2ip nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein IAGP MGI PMID:20133688 NCBI chr 7:125,982,025...125,995,909
Ensembl chr 7:125,982,026...125,995,909 		JBrowse link
G Sele selectin, endothelial cell IAGP MGI PMID:17456770 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246 		JBrowse link
G Selp selectin, platelet IAGP MGI PMID:17456770 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595 		JBrowse link
G Srgn serglycin IAGP MGI PMID:15231821 NCBI chr10:62,329,612...62,363,224
Ensembl chr10:62,329,612...62,363,230 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A IAGP MGI PMID:15947484 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
increased mast cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen dependent TFPI regulating protein IAGP MGI PMID:30571485 NCBI chr13:41,916,621...42,001,092
Ensembl chr13:41,916,624...42,001,160 		JBrowse link
G Agr2 anterior gradient 2 IAGP MGI PMID:19359471 NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086 		JBrowse link
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:18077429 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Casp8 caspase 8 IAGP MGI PMID:21135236 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 IAGP MGI PMID:25692702 NCBI chr10:24,649,712...24,712,093
Ensembl chr10:24,648,304...24,718,721 		JBrowse link
G Fbn1 fibrillin 1 IAGP MGI PMID:4048170 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 IAGP MGI PMID:25843682 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IAGP MGI PMID:25843682 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:20512127 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:12754375 PMID:22652566 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kitl kit ligand IAGP MGI PMID:7533739 PMID:19874813 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:20512127 NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 IAGP MGI PMID:25692702 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Runx1 runt related transcription factor 1 IAGP MGI PMID:16247465 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037 		JBrowse link
G Sele selectin, endothelial cell IAGP MGI PMID:17456770 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246 		JBrowse link
G Spred1 sprouty protein with EVH-1 domain 1, related sequence IAGP MGI PMID:21668589 NCBI chr 2:116,951,576...117,012,760
Ensembl chr 2:116,951,855...117,012,760 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16963
    hematopoietic system phenotype 5543
      abnormal hematopoietic system morphology/development 5069
        abnormal hematopoietic cell morphology 4235
          abnormal leukocyte morphology 2821
            abnormal leukocyte cell number 2533
              abnormal granulocyte number 897
                abnormal mast cell number 42
                  decreased mast cell number + 22
                  increased mast cell number + 26
Path 2
Term Annotations click to browse term
  mammalian phenotype 16963
    hematopoietic system phenotype 5543
      abnormal hematopoietic system morphology/development 5069
        abnormal hematopoietic cell morphology 4235
          abnormal myeloid cell morphology 3075
            abnormal myeloid leukocyte morphology 1460
              abnormal granulocyte morphology 929
                abnormal granulocyte number 897
                  abnormal mast cell number 42
                    decreased mast cell number + 22
                    increased mast cell number + 26
paths to the root