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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal adenoma incidence
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Accession:MP:0020189 term browser browse the term
Definition:an anomaly in the expected number of a benign epithelial neoplasm with a glandular organization, occurring in a specific population in a given time period; this tumor type usually does not invade or infiltrate surrounding tissue but may remain a benign tumor or progress to malignancy



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increased colon adenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
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G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201

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  mammalian phenotype 5364
    neoplasm 243
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          abnormal classified tumor incidence 105
            abnormal adenoma incidence 15
              abnormal lung adenoma incidence + 0
              increased adenoma incidence + 15
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