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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased response to brain injury
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Accession:MP:0014523 term browser browse the term
Definition:more severe response, such as increased incidence and/or size of necrotic tissue, to acquired brain injury, including trauma caused by physical means (e.g. shocks, concussions, or incisions), lack of adequate blood flow, exposure to toxins or cold-induced stress, pressure from a tumor, etc.
Synonyms:exact_synonym: enhanced response to brain injury
 narrow_synonym: decreased resistance to brain injury;   elevated susceptibility to brain injury;   reduced resistance to brain injury



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increased susceptibility to ischemic brain injury term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IDA RGD PMID:14502288 RGD:734740 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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  mammalian phenotype 5422
    homeostasis/metabolism phenotype 1426
      abnormal response to injury 39
        abnormal response to brain injury 18
          increased response to brain injury 9
            increased susceptibility to ischemic brain injury + 9
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