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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating interleukin level
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Accession:MP:0014498 term browser browse the term
Definition:decrease in the amount in the blood of soluble factors which stimulate growth-related activities of leukocytes as well as other cell type
Synonyms:exact_synonym: reduced circulating IL level



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decreased circulating interleukin-10 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfb complement factor B IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfbem1Tja complement factor B, ZFN induced mutant 1, Tja IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403
decreased circulating interleukin-6 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    immune system phenotype 519
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                decreased circulating interleukin level 7
                  decreased circulating interleukin-1 level + 1
                  decreased circulating interleukin-10 level 4
                  decreased circulating interleukin-12 level + 0
                  decreased circulating interleukin-12b level 0
                  decreased circulating interleukin-13 level 0
                  decreased circulating interleukin-15 level 0
                  decreased circulating interleukin-16 level 0
                  decreased circulating interleukin-17 level 0
                  decreased circulating interleukin-18 level 0
                  decreased circulating interleukin-2 level 0
                  decreased circulating interleukin-21 level 0
                  decreased circulating interleukin-23 level 0
                  decreased circulating interleukin-3 level 0
                  decreased circulating interleukin-4 level 1
                  decreased circulating interleukin-5 level 0
                  decreased circulating interleukin-6 level 3
                  decreased circulating interleukin-7 level 0
                  decreased circulating interleukin-8 level 0
                  decreased circulating interleukin-9 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  decreased circulating interleukin level 7
                    decreased circulating interleukin-1 level + 1
                    decreased circulating interleukin-10 level 4
                    decreased circulating interleukin-12 level + 0
                    decreased circulating interleukin-12b level 0
                    decreased circulating interleukin-13 level 0
                    decreased circulating interleukin-15 level 0
                    decreased circulating interleukin-16 level 0
                    decreased circulating interleukin-17 level 0
                    decreased circulating interleukin-18 level 0
                    decreased circulating interleukin-2 level 0
                    decreased circulating interleukin-21 level 0
                    decreased circulating interleukin-23 level 0
                    decreased circulating interleukin-3 level 0
                    decreased circulating interleukin-4 level 1
                    decreased circulating interleukin-5 level 0
                    decreased circulating interleukin-6 level 3
                    decreased circulating interleukin-7 level 0
                    decreased circulating interleukin-8 level 0
                    decreased circulating interleukin-9 level 0
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