MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: decreased circulating hormone level
Accession: MP:0014457
browse the term
Definition: reduction in the blood concentration of any of the chemical substances that have specific regulatory effects on the activity of a certain organ or organ
Synonyms: exact_synonym: reduced circulating hormone concentration
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Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
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Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
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Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
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Ahr
aryl hydrocarbon receptor
IMP
RGD
PMID:34256052
RGD:405878088
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Ahrem1Soar
aryl hydrocarbon receptor; CRISPR/Cas9 induced mutant1, Soar
IMP
RGD
PMID:34256052
RGD:405878088
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Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
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Tspo
translocator protein
induces
IMP
RGD
PMID:29074640
RGD:150429771
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
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Tspoem1Vpl
translocator protein; ZFN induced mutant1, Vpl
induces
IMP
RGD
PMID:29074640
RGD:150429771
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Tspoem2Vpl
translocator protein; ZFN induced mutant2, Vpl
induces
IMP
RGD
PMID:29074640
RGD:150429771
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Crh
corticotropin releasing hormone
IDA
RGD
PMID:12450317
RGD:704424
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Esr2
estrogen receptor 2
IMP
RGD
PMID:28520870
RGD:38548924
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
RGD
PMID:28520870
RGD:38548924
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Esr2
estrogen receptor 2
IMP
RGD
PMID:28520870
RGD:38548924
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
RGD
PMID:28520870
RGD:38548924
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Wwox
WW domain-containing oxidoreductase
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
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Wwoxlde
WW domain-containing oxidoreductase; lde mutant
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
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Ghsr
growth hormone secretagogue receptor
IMP
DNA:missense mutation:cds:nucleotide 1027
RGD
PMID:27129673
RGD:150520013
NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
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Ghsrm1Mcwi
growth hormone secretagogue receptor; mutation 1, Medical College of Wisconsin
IMP
compared to wild type rats in response to ghrelin (CHEBI:75431)
RGD
PMID:27129673
RGD:150520013
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Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
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Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
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Tbc1d1
TBC1 domain family member 1
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
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Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
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Cftr
CF transmembrane conductance regulator
IMP
RGD
PMID:29190650
RGD:151347176
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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Cftrem1Sage
cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage
IMP
RGD
PMID:29190650
RGD:151347176
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Bscl2
BSCL2 lipid droplet biogenesis associated, seipin
IMP
RGD
PMID:25934999
RGD:11085488
NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
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Bscl2m1Kyo
BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo
IMP
RGD
PMID:25934999
RGD:11085488
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Ghsr
growth hormone secretagogue receptor
IMP
RGD
PMID:19931319
RGD:12910109
NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
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Pmch
pro-melanin-concentrating hormone
IMP
compared to wild-type
RGD
PMID:23555928 PMID:19934402
RGD:150429944 , RGD:150429945
NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
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Pmchm1Hubr
pro-melanin-concentrating hormone; ENU induced mutant1, Hubr
IMP
compared to wild-type
RGD
PMID:23555928 PMID:19934402
RGD:150429944 , RGD:150429945
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Tg
thyroglobulin
IAGP
RGD
PMID:10760744
RGD:13605608
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
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Tgrdw
thyroglobulin; rdw mutant
IAGP
RGD
PMID:10760744
RGD:13605608
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Esr2
estrogen receptor 2
IMP
RGD
PMID:28520870
RGD:38548924
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
RGD
PMID:28520870
RGD:38548924
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Kiss1
KiSS-1 metastasis-suppressor
IMP
RGD
PMID:25582792
RGD:10059342
NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
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Kiss1tm1Nips
KiSS-1 metastasis-suppressor; targeted mutant 1, Nips
IMP
RGD
PMID:25582792
RGD:10059342
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Wwox
WW domain-containing oxidoreductase
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
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Wwoxlde
WW domain-containing oxidoreductase; lde mutant
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
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Crh
corticotropin releasing hormone
IDA
RGD
PMID:12450317
RGD:704424
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Esr2
estrogen receptor 2
IMP
RGD
PMID:29580824
RGD:38548925
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
compared to wild type
RGD
PMID:29580824
RGD:38548925
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Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
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Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
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Dhh
desert hedgehog signaling molecule
IMP
RGD
PMID:21062903
RGD:38548923
NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
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Tspo
translocator protein
IMP
RGD
PMID:29074640
RGD:150429771
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
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Tspoem1Vpl
translocator protein; ZFN induced mutant1, Vpl
IMP
RGD
PMID:29074640
RGD:150429771
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Tspoem2Vpl
translocator protein; ZFN induced mutant2, Vpl
IMP
RGD
PMID:29074640
RGD:150429771
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Wwox
WW domain-containing oxidoreductase
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
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Wwoxlde
WW domain-containing oxidoreductase; lde mutant
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
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Tshr
thyroid stimulating hormone receptor
IMP
RGD
PMID:29507327
RGD:150521601
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
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Tshrem1Mlit
thyroid stimulating hormone receptor; CRISPR/Cas9 induced mutant 1, Mlit
IMP
RGD
PMID:29507327
RGD:150521601
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Tshr
thyroid stimulating hormone receptor
IMP
RGD
PMID:29507327
RGD:150521601
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
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Tshrem1Mlit
thyroid stimulating hormone receptor; CRISPR/Cas9 induced mutant 1, Mlit
IMP
RGD
PMID:29507327
RGD:150521601
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