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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating enzyme level
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Accession:MP:0014451 term browser browse the term
Definition:reduced concentration in the blood of any of the proteins that act as catalysts for biological reactions
Synonyms:exact_synonym: reduced circulating enzyme level



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decreased circulating alanine transaminase level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:30249809 RGD:41404725 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf1rtm(EGFP)Tset colony stimulating factor 1 receptor; target mutant, Tset IMP RGD PMID:30249809 RGD:41404725
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:23799078 RGD:13462048 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:23799078 RGD:13462048
decreased circulating alkaline phosphatase level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Htr7 5-hydroxytryptamine receptor 7 IMP in male RGD PMID:31125290 RGD:14696717 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Htr7em1Msu 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu IMP in male RGD PMID:31125290 RGD:14696717
decreased circulating aspartate transaminase level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:23799078 RGD:13462048 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 RGD:38596340 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 RGD:38596340
decreased circulating lactate dehydrogenase level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
decreased circulating renin level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IMP compared to wild type RGD PMID:26077568 RGD:13800514 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd11b2em1Jmul hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul IMP compared to wild type RGD PMID:26077568 RGD:13800514

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5421
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal enzyme/coenzyme level 86
          abnormal circulating enzyme level 63
            decreased circulating enzyme level 25
              decreased circulating alanine transaminase level 10
              decreased circulating alkaline phosphatase level 7
              decreased circulating amylase level 0
              decreased circulating arginase level 0
              decreased circulating aspartate transaminase level 8
              decreased circulating creatine kinase level 0
              decreased circulating factor IX level 0
              decreased circulating factor X level 0
              decreased circulating factor XI level 0
              decreased circulating factor XII level 0
              decreased circulating factor XIII level 0
              decreased circulating glutamate dehydrogenase level 0
              decreased circulating lactate dehydrogenase level 3
              decreased circulating lipase level 0
              decreased circulating renin level 5
Path 2
Term Annotations click to browse term
  mammalian phenotype 5421
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal blood homeostasis 764
          abnormal circulating protein level 109
            abnormal circulating enzyme level 63
              decreased circulating enzyme level 25
                decreased circulating alanine transaminase level 10
                decreased circulating alkaline phosphatase level 7
                decreased circulating amylase level 0
                decreased circulating arginase level 0
                decreased circulating aspartate transaminase level 8
                decreased circulating creatine kinase level 0
                decreased circulating factor IX level 0
                decreased circulating factor X level 0
                decreased circulating factor XI level 0
                decreased circulating factor XII level 0
                decreased circulating factor XIII level 0
                decreased circulating glutamate dehydrogenase level 0
                decreased circulating lactate dehydrogenase level 3
                decreased circulating lipase level 0
                decreased circulating renin level 5
paths to the root