Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal intracellular organelle morphology
go back to main search page
Accession:MP:0014239 term browser browse the term
Definition:any anomaly in the structure of the organized components of distincive morphology and function that occur within a cell



show annotations for term's descendants           Sort by:
abnormal actin cytoskeleton morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add3 adducin 3 IMP RGD PMID:32029431 RGD:150340736 NCBI chr 1:262,152,722...262,260,504 JBrowse link
abnormal endoplasmic reticulum morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myo5a myosin VA IAGP DNA:rearrangement, deletion:exon:141-bp deletion position 1442-1582 RGD PMID:17185506 RGD:1600835 NCBI chr 8:84,692,524...84,860,564 JBrowse link
G Tg thyroglobulin IAGP DNA:missense mutation:cds:p.G2320R (rat) RGD PMID:11089535 RGD:730133 NCBI chr 7:98,418,293...98,603,210 JBrowse link
G Tgrdw thyroglobulin; rdw mutant IAGP compared to wild type and heterozygotes RGD PMID:11089535 RGD:730133
abnormal lysosome morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha IMP compared to wild type RGD PMID:34320241 PMID:34541380 RGD:401976418, RGD:401976419 NCBI chr  X:102,062,497...102,073,915 JBrowse link
G Glaem2Mcwi galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin IMP compared to wild type RGD PMID:34320241 PMID:34541380 RGD:401976418, RGD:401976419
abnormal mitochondrial crista morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:22629444 RGD:7240532 NCBI chr 7:95,483,105...95,488,031 JBrowse link
abnormal vacuole morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 IMP seminiferous tubule; compared to SD RGD PMID:28834365 RGD:14995504 NCBI chr10:54,798,871...54,810,300 JBrowse link
G Tp53em1Sage tumor protein p53; ZFN induced mutant 1, Sage IMP seminiferous tubule; compared to SD RGD PMID:28834365 RGD:14995504
accumulation of giant lysosomes in kidney/renal tubule cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725 JBrowse link
binucleate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cit citron rho-interacting serine/threonine kinase IAGP RGD PMID:11932363 RGD:13204832 NCBI chr12:46,263,881...46,425,642 JBrowse link
G CitfhJjlo citron rho-interacting serine/threonine kinase; flat head mutant, Jjlo IAGP RGD PMID:11932363 RGD:13204832
decreased mitochondrial DNA content term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IMP RGD PMID:31644904 RGD:126925983 NCBI chr16:7,771,311...7,841,895 JBrowse link
G Ercc6em1Cgen ERCC excision repair 6, chromatin remodeling factor; CRISPR/Cas9 induced mutant 1, Cgen IMP RGD PMID:31644904 RGD:126925983
decreased mitochondrial size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:22629444 RGD:7240532 NCBI chr 7:95,483,105...95,488,031 JBrowse link
increased mitochondrial size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin IMP RGD PMID:29223733 RGD:401793739 NCBI chr 1:231,300,457...231,323,989 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5421
    cellular phenotype 184
      abnormal cell morphology 47
        abnormal intracellular organelle morphology 23
          abnormal Golgi apparatus morphology + 1
          abnormal cell cytoskeleton morphology + 2
          abnormal cell nucleus morphology + 3
          abnormal chromatoid body morphology 0
          abnormal endoplasmic reticulum morphology 5
          abnormal mitochondrial morphology + 5
          abnormal peroxisome morphology 0
          abnormal ribosome morphology 0
          abnormal sperm cytoplasmic droplet morphology + 0
          abnormal vacuole morphology + 7
paths to the root