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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased pancreatic islet cell apoptosis
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Accession:MP:0014121 term browser browse the term
Definition:increase in the number of pancreatic islet cells undergoing programmed cell death


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increased pancreatic islet cell apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IAGP MGI PMID:26518685 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604 		JBrowse link
G Atf6 activating transcription factor 6 IAGP MGI PMID:24225943 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340 		JBrowse link
G Cd38 CD38 antigen IAGP MGI PMID:17003338 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Clock clock circadian regulator IAGP MGI PMID:20562852 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639 		JBrowse link
G Col5a3 collagen, type V, alpha 3 IAGP MGI PMID:21293061 NCBI chr 9:20,681,353...20,726,363
Ensembl chr 9:20,681,346...20,726,363 		JBrowse link
G Ins2 insulin II IAGP MGI PMID:19955657 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Kcnh6 potassium voltage-gated channel, subfamily H (eag-related), member 6 IAGP MGI PMID:30590050 NCBI chr11:105,898,871...105,926,421
Ensembl chr11:105,898,950...105,925,375 		JBrowse link
G Lepr leptin receptor IAGP MGI PMID:19955657 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
increased pancreatic beta cell apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IAGP MGI PMID:26518685 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604 		JBrowse link
G Alx3 aristaless-like homeobox 3 IAGP MGI PMID:21104068 NCBI chr 3:107,502,347...107,513,191
Ensembl chr 3:107,502,347...107,513,092 		JBrowse link
G Bad BCL2-associated agonist of cell death IAGP MGI PMID:18223655 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Cdk8 cyclin dependent kinase 8 IAGP MGI PMID:31509750 NCBI chr 5:146,167,432...146,239,684
Ensembl chr 5:146,168,040...146,239,684 		JBrowse link
G Col5a3 collagen, type V, alpha 3 IAGP MGI PMID:21293061 NCBI chr 9:20,681,353...20,726,363
Ensembl chr 9:20,681,346...20,726,363 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 IAGP MGI PMID:24336520 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109 		JBrowse link
G Ins2 insulin II IAGP MGI PMID:32640216 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Jazf1 JAZF zinc finger 1 IAGP MGI PMID:32640216 NCBI chr 6:52,745,050...53,045,613
Ensembl chr 6:52,745,782...53,045,616 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IAGP MGI PMID:20811152 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 IAGP MGI PMID:19934005 NCBI chr 6:88,480,589...88,495,782
Ensembl chr 6:88,480,561...88,495,887 		JBrowse link
G Senp1 SUMO1/sentrin specific peptidase 1 IAGP MGI PMID:26596471 NCBI chr15:97,936,625...97,991,625
Ensembl chr15:97,936,625...97,991,625 		JBrowse link
G Tgfbi transforming growth factor, beta induced IAGP MGI PMID:24728038 NCBI chr13:56,757,399...56,787,172
Ensembl chr13:56,757,336...56,787,375 		JBrowse link
G Uox urate oxidase IAGP MGI PMID:28729031 NCBI chr 3:146,302,904...146,337,238
Ensembl chr 3:146,276,181...146,338,060 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    endocrine/exocrine gland phenotype 3407
      abnormal gland physiology 909
        abnormal pancreas physiology 382
          abnormal pancreatic islet cell apoptosis 27
            increased pancreatic islet cell apoptosis 18
              increased pancreatic beta cell apoptosis 13
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    cellular phenotype 5391
      abnormal cell physiology 4790
        abnormal cell death 2117
          abnormal programmed cell death 1731
            abnormal apoptosis 1725
              abnormal pancreatic islet cell apoptosis 27
                increased pancreatic islet cell apoptosis 18
                  increased pancreatic beta cell apoptosis 13
paths to the root