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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal colon goblet cell morphology
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Accession:MP:0013795 term browser browse the term
Definition:any structural anomaly of the glandular simple columnar epithelial cell found in the mucosal lining of the colon, whose primary function is to secrete gel-forming mucins, the major components of mucus
Synonyms:exact_synonym: abnormal colonic goblet cell morphology


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abnormal colon goblet cell morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:17332369 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Bdnf brain derived neurotrophic factor IAGP MGI PMID:10514401 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator IAGP MGI PMID:7527588 PMID:8589719 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G E2f4 E2F transcription factor 4 IAGP MGI PMID:10983977 NCBI chr 8:106,024,295...106,032,002
Ensembl chr 8:106,024,295...106,032,002 		JBrowse link
G Ednrb endothelin receptor type B IAGP MGI PMID:24945437 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) IAGP MGI PMID:17332369 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) IAGP MGI PMID:17332369 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D IAGP MGI PMID:33219235 NCBI chr14:14,091,010...14,120,836
Ensembl chr14:14,091,019...14,120,836 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IAGP MGI PMID:20190135 NCBI chr 6:48,723,131...48,731,134
Ensembl chr 6:48,723,131...48,731,144 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:18372904 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 IAGP MGI PMID:15121863 NCBI chr11:95,847,989...95,896,770
Ensembl chr11:95,847,989...95,896,766 		JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) IAGP MGI PMID:12015290 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:18372904 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lep leptin IAGP MGI PMID:16455789 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated IAGP MGI PMID:24442434 NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109 		JBrowse link
G Slc9a8 solute carrier family 9 (sodium/hydrogen exchanger), member 8 IAGP MGI PMID:22575219 NCBI chr 2:167,261,678...167,318,920
Ensembl chr 2:167,263,632...167,318,920 		JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box IAGP MGI PMID:21383188 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086 		JBrowse link
G Zranb1 zinc finger, RAN-binding domain containing 1 IAGP MGI PMID:36087511 NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120 		JBrowse link
decreased colon goblet cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif 18 IAGP MGI PMID:28145888 NCBI chr 8:114,423,755...114,575,975
Ensembl chr 8:114,423,758...114,575,370 		JBrowse link
G Gpa33 glycoprotein A33 transmembrane IAGP MGI PMID:19856415 NCBI chr 1:165,957,790...165,994,079
Ensembl chr 1:165,957,807...165,994,079 		JBrowse link
G Misp mitotic spindle positioning IAGP MGI PMID:36596561 NCBI chr10:79,656,853...79,666,286
Ensembl chr10:79,656,823...79,666,324 		JBrowse link
G Prss8 serine protease 8 (prostasin) IAGP MGI PMID:29617460 NCBI chr 7:127,524,889...127,529,266
Ensembl chr 7:127,524,888...127,529,276 		JBrowse link
G Slc12a2 solute carrier family 12, member 2 IAGP MGI PMID:31655271 NCBI chr18:58,011,505...58,079,893
Ensembl chr18:58,011,750...58,079,893 		JBrowse link
G Spint2 serine protease inhibitor, Kunitz type 2 IAGP MGI PMID:29617460 NCBI chr 7:28,955,755...28,981,484
Ensembl chr 7:28,955,748...28,981,337 		JBrowse link
G Tvp23b trans-golgi network vesicle protein 23B IAGP MGI PMID:37339972 NCBI chr11:62,770,281...62,786,012
Ensembl chr11:62,770,281...62,807,606 		JBrowse link
increased colon goblet cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Filip1l filamin A interacting protein 1-like IAGP MGI PMID:34417201 NCBI chr16:57,173,376...57,393,167
Ensembl chr16:57,173,456...57,393,489 		JBrowse link
G Lpo lactoperoxidase IAGP MGI PMID:34127712 NCBI chr11:87,697,254...87,716,750
Ensembl chr11:87,697,254...87,719,115 		JBrowse link
G Ndst4 N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4 IAGP MGI PMID:27793051 NCBI chr 3:125,197,678...125,522,550
Ensembl chr 3:125,197,725...125,522,548 		JBrowse link
G Nup35 nucleoporin 35 IAGP MGI PMID:27427419 NCBI chr 2:80,469,156...80,490,415
Ensembl chr 2:80,447,580...80,489,250 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    cellular phenotype 5391
      abnormal cell morphology 1966
        abnormal intestinal goblet cell morphology 91
          abnormal large intestine goblet cell morphology 31
            abnormal colon goblet cell morphology 29
              abnormal colon goblet cell number + 11
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    digestive/alimentary phenotype 1890
      abnormal digestive system morphology 1498
        abnormal intestine morphology 673
          abnormal intestinal mucosa morphology 262
            abnormal crypts of Lieberkuhn morphology 206
              abnormal large intestine crypts of Lieberkuhn morphology 74
                abnormal large intestine goblet cell morphology 31
                  abnormal colon goblet cell morphology 29
                    abnormal colon goblet cell number + 11
paths to the root