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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal Herring body morphology
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Accession:MP:0013491 term browser browse the term
Definition:any structural anomaly of the dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary; Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release; each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively
Synonyms:exact_synonym: abnormal Herring bodies;   abnormal neurosecretory body morphology



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    nervous system phenotype 376
      abnormal nervous system morphology 214
        abnormal neuron morphology 70
          abnormal neuroendocrine cell morphology 0
            abnormal Herring body morphology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    endocrine/exocrine gland phenotype 394
      abnormal gland morphology 333
        abnormal endocrine gland morphology 164
          abnormal neuroendocrine gland morphology 42
            abnormal neuroendocrine cell morphology 0
              abnormal Herring body morphology 0
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