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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:dysmyelination
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Accession:MP:0013438 term browser browse the term
Definition:reduced amount of myelin present in the form of a myelin sheath surrounding an axon due to defects in the synthesis and formation of myelin
Comment:Dysmyelination refers to malformed and defective myelin sheath as opposed to the destruction of previously normal myelin that is seen in demyelination. Dysmyelination disorders often arise from hereditary mutations that affect the synthesis and formation of myelin.
Synonyms:exact_synonym: hypomyelination;   reduced myelination


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  mammalian phenotype 0
    nervous system phenotype 0
      abnormal nervous system physiology 0
        abnormal myelination 0
          dysmyelination 0
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