MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number
Accession: MP:0013433
browse the term
Definition: increase in the number of KLRG1+ CD4+, CD25+, alpha-beta regulatory T cell number positive for KLRG1, a marker associated with activation
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Arhgef1
Rho guanine nucleotide exchange factor 1
IEA
MGI
NCBI chr 7:24,601,762...24,626,019
Ensembl chr 7:24,602,337...24,626,019
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Arpc1b
actin related protein 2/3 complex, subunit 1B
IEA
MGI
NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515
G
Bach2
BTB and CNC homology, basic leucine zipper transcription factor 2
IEA
MGI
NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108
G
Cog6
component of oligomeric golgi complex 6
IEA
MGI
NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658
G
Dph6
diphthamine biosynthesis 6
IEA
MGI
NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445
G
Il27
interleukin 27
IEA
MGI
NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113
G
Sik3
SIK family kinase 3
IEA
MGI
NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
mammalian phenotype
17090
immune system phenotype
5776
abnormal immune system morphology
4139
abnormal immune system cell morphology
2913
abnormal leukocyte morphology
2894
abnormal leukocyte cell number
2604
abnormal lymphocyte cell number
1738
abnormal T cell number
1090
abnormal regulatory T cell number
168
increased regulatory T cell number
85
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
35
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number
7
Path 2
mammalian phenotype
17090
immune system phenotype
5776
abnormal immune system morphology
4139
abnormal immune system cell morphology
2913
abnormal leukocyte morphology
2894
abnormal mononuclear cell morphology
2314
abnormal lymphocyte morphology
1876
abnormal T cell morphology
1188
abnormal effector T cell morphology
870
abnormal CD4-positive, alpha beta T cell morphology
612
abnormal CD4-positive, alpha-beta T cell number
525
increased CD4-positive, alpha-beta T cell number
290
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
35
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number
7