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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number
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Accession:MP:0013428 term browser browse the term
Definition:anomaly in the number of the CD4+, CD25+ alpha-beta regulatory T cells with a CD44+ CD62L- memory phenotype


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decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,088
Ensembl chr 2:122,129,381...122,133,366 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Cttnbp2 cortactin binding protein 2 IEA MGI NCBI chr 6:18,366,470...18,515,216
Ensembl chr 6:18,366,477...18,514,842 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Pclaf PCNA clamp associated factor IEA MGI NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548 		JBrowse link
G Pepd peptidase D IEA MGI NCBI chr 7:34,611,832...34,744,131
Ensembl chr 7:34,611,804...34,744,133 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17088
    immune system phenotype 5775
      abnormal immune system morphology 4141
        abnormal immune system cell morphology 2914
          abnormal leukocyte morphology 2895
            abnormal leukocyte cell number 2606
              abnormal lymphocyte cell number 1738
                abnormal T cell number 1090
                  abnormal regulatory T cell number 168
                    abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number 54
                      abnormal memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 10
                        decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 2
                        increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 9
Path 2
Term Annotations click to browse term
  mammalian phenotype 17088
    immune system phenotype 5775
      abnormal immune system morphology 4141
        abnormal immune system cell morphology 2914
          abnormal leukocyte morphology 2895
            abnormal mononuclear cell morphology 2315
              abnormal lymphocyte morphology 1876
                abnormal T cell morphology 1188
                  abnormal effector T cell morphology 870
                    abnormal CD4-positive, alpha beta T cell morphology 612
                      abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology 58
                        abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number 54
                          abnormal memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 10
                            decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 2
                            increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 9
paths to the root