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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal adenohypophysis development
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Accession:MP:0013337 term browser browse the term
Definition:aberrant formation or incomplete differentiation of the anterior lobe of the pituitary gland which arises as a pouch-like outgrowth of ectoderm known as the hypophyseal (Rathke's) pouch from the dorsal midline roof of the stomodeum (primitive oral cavity); the hypophyseal pouch grows toward the brain and the neurohypophyseal bud; as the hypophyseal pouch and the infundibulum make contact, the hypophyseal pouch loses its connection with the pharynx, creating a hollow ball of cells that lies inferior to the floor of the diencephalon posterior to the optic chiasm; these cells undergo division, the central chamber gradually disappears, and this endocrine mass becomes the anterior pituitary gland; the fully developed adenohypophysis consists of a glandular pars distalis, a thin proximal extension called the pars tuberalis, and a narrow pars intermedia
Synonyms:exact_synonym: abnormal adenophysis development;   abnormal anterior pituitary development;   abnormal anterior pituitary gland development;   abnormal anterior pituitary lobe development


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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    endocrine/exocrine gland phenotype 0
      abnormal gland morphology 0
        abnormal gland development 0
          abnormal pituitary gland development 0
            abnormal adenohypophysis development 0
              abnormal pituitary diverticulum morphology + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    nervous system phenotype 0
      abnormal nervous system morphology 0
        abnormal brain morphology 0
          abnormal forebrain morphology 0
            abnormal diencephalon morphology 0
              abnormal pituitary gland morphology 0
                abnormal pituitary gland development 0
                  abnormal adenohypophysis development 0
                    abnormal pituitary diverticulum morphology + 0
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