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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal translation
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Accession:MP:0013272 term browser browse the term
Definition:any anomaly in the cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain; translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA; translation ends with the release of a polypeptide chain from the ribosome
Synonyms:exact_synonym: abnormal protein anabolism;   abnormal protein biosynthesis;   abnormal protein biosynthetic process;   abnormal protein formation;   abnormal protein synthesis;   abnormal protein translation


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  mammalian phenotype 5402
    homeostasis/metabolism phenotype 1418
      abnormal metabolism 75
        abnormal translation 0
          abnormal translational elongation + 0
Path 2
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  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell physiology 145
        abnormal intracellular organelle physiology 22
          abnormal translation 0
            abnormal translational elongation + 0
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