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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal Ly6C high monocyte number
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Accession:MP:0013021 term browser browse the term
Definition:deviation in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues


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decreased Ly6C high monocyte number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l11 BCL2 like 11 IAGP MGI PMID:27525555 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D IAGP MGI PMID:29853563 NCBI chr14:14,091,010...14,120,836
Ensembl chr14:14,091,019...14,120,836 		JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:26867177 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329 		JBrowse link
G Morrbid myeloid RNA regulator of BCL2L11 induced cell death IAGP MGI PMID:27525555 NCBI chr 2:128,140,583...128,271,271
Ensembl chr 2:128,020,239...128,344,685 		JBrowse link
G Nup85 nucleoporin 85 IAGP MGI PMID:32001710 NCBI chr11:115,455,264...115,474,750
Ensembl chr11:115,455,260...115,474,811 		JBrowse link
G Tmem127 transmembrane protein 127 IEA MGI NCBI chr 2:127,089,868...127,103,028
Ensembl chr 2:127,089,828...127,103,027 		JBrowse link
increased Ly6C high monocyte number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm2 adrenomedullin 2 IAGP MGI PMID:29980671 NCBI chr15:89,206,923...89,208,934
Ensembl chr15:89,206,923...89,208,934 		JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:19858416 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Cbs cystathionine beta-synthase IAGP MGI PMID:19858416 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit IEA MGI NCBI chr17:57,297,264...57,303,371
Ensembl chr17:57,297,305...57,303,188 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IEA MGI NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 IAGP MGI PMID:36656709 NCBI chr 4:134,083,684...134,099,893
Ensembl chr 4:134,083,683...134,111,161 		JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 IEA MGI NCBI chr 9:66,257,694...66,416,057
Ensembl chr 9:66,257,732...66,416,057 		JBrowse link
G N4bp1 NEDD4 binding protein 1 IAGP MGI PMID:32971525 NCBI chr 8:87,567,764...87,612,489
Ensembl chr 8:87,534,788...87,611,886 		JBrowse link
G Stim1 stromal interaction molecule 1 IAGP MGI PMID:31666234 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 IAGP MGI PMID:26015500 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786 		JBrowse link
G Trappc9 trafficking protein particle complex 9 IEA MGI NCBI chr15:72,461,469...72,933,086
Ensembl chr15:72,461,469...72,933,053 		JBrowse link
G Trim31 tripartite motif-containing 31 IAGP MGI PMID:27929086 NCBI chr17:37,209,022...37,221,109
Ensembl chr17:37,209,010...37,221,106 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16963
    immune system phenotype 5709
      abnormal immune system morphology 4077
        abnormal immune system cell morphology 2842
          abnormal leukocyte morphology 2821
            abnormal leukocyte cell number 2532
              abnormal monocyte cell number 366
                abnormal Ly6C high monocyte number 20
                  decreased Ly6C high monocyte number 6
                  increased Ly6C high monocyte number 14
Path 2
Term Annotations click to browse term
  mammalian phenotype 16963
    hematopoietic system phenotype 5542
      abnormal hematopoietic system morphology/development 5068
        abnormal hematopoietic cell morphology 4234
          abnormal leukocyte morphology 2821
            abnormal myeloid leukocyte morphology 1461
              abnormal phagocyte morphology 1208
                abnormal mononuclear phagocyte morphology 872
                  abnormal monocyte morphology 374
                    abnormal monocyte cell number 366
                      abnormal Ly6C high monocyte number 20
                        decreased Ly6C high monocyte number 6
                        increased Ly6C high monocyte number 14
paths to the root