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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal enteric neural crest cell migration
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Accession:MP:0013006 term browser browse the term
Definition:any anomaly in the migratory path or behavior of the neural crest cells (NCCs) that arise predominantly from the vagal (neck) region of the neural tube (vagal neural crest), adjacent to somites 1-7, and migrate rostro-caudally along the gastrointestinal tract to form two ganglionated plexuses of neurons and glial cells that comprise the enteric nervous system (ENS); a smaller proportion of ENCCs come from the sacral neural crest, caudal to somite 28, and migrate caudo-rostrally to colonize the distal gut; NCCs are termed enteric neural crest-derived cells upon entering the foregut at E9-9.5 in mice (after 4 weeks gestation in humans) and the colonization process is complete by E15.5 (after 7 weeks gestation in humans)
Synonyms:exact_synonym: abnormal ENCC migration;   abnormal ENCDC migration;   abnormal enteric neural crest-derived cell migration


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  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell physiology 145
        abnormal neural crest cell physiology 0
          abnormal neural crest cell migration 0
            abnormal enteric neural crest cell migration 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell physiology 145
        abnormal cell motility 3
          abnormal cell migration 0
            abnormal neural crest cell migration 0
              abnormal enteric neural crest cell migration 0
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