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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number
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Accession:MP:0012773 term browser browse the term
Definition:any anomaly in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release


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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system cell morphology 0
          abnormal leukocyte morphology 0
            abnormal leukocyte cell number 0
              abnormal lymphocyte cell number 0
                abnormal T cell number 0
                  abnormal regulatory T cell number 0
                    abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
                      abnormal KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
                      abnormal memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
                      decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
                      increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system cell morphology 0
          abnormal leukocyte morphology 0
            abnormal mononuclear cell morphology 0
              abnormal lymphocyte morphology 0
                abnormal T cell morphology 0
                  abnormal effector T cell morphology 0
                    abnormal CD4-positive, alpha beta T cell morphology 0
                      abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology 0
                        abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
                          abnormal KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
                          abnormal memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
                          decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
                          increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
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